Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments

Autores
Cansolino, L.; Clerici, A.M.; Zonta, C.; Dionigi, P.; Mazzini, G.; Di Liberto, R.; Altieri, S.; Ballarini, F.; Bortolussi, S.; Carante, M.P.; Ferrari, M.; González, Sara Josefina; Postuma, I.; Protti, N.; Santa Cruz, G.A.; Ferrari, C.
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The present work is part of a preclinical in vitro study to assess the efficacy of BNCT applied to liver or lung coloncarcinoma metastases and to limb osteosarcoma. Adherent growing cell lines can be irradiated as adherent to the culture flasks or as cell suspensions, differences in radio-sensitivity of the two modalities of radiation exposure have been investigated. Dose related cell survival and cell cycle perturbation results evidenced that the radiosensitivity of adherent cells is higher than that of the suspended ones.
Fil: Cansolino, L.. University of Pavia; Italia. Matteo Hospital; Italia
Fil: Clerici, A.M.. University of Pavia; Italia
Fil: Zonta, C.. University of Pavia; Italia
Fil: Dionigi, P.. University of Pavia; Italia. Matteo Hospital; Italia
Fil: Mazzini, G.. University of Pavia; Italia
Fil: Di Liberto, R.. Matteo Hospital; Italia
Fil: Altieri, S.. Istituto Nazionale Di Fisica Nucleare, Sezione Di Pavia; . Università Degli Studi Di Pavia;
Fil: Ballarini, F.. University of Pavia; Italia. Istituto Nazionale Di Fisica Nucleare; Italia
Fil: Bortolussi, S.. Istituto Nazionale Di Fisica Nucleare; Italia
Fil: Carante, M.P.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Ferrari, M.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Postuma, I.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Protti, N.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Santa Cruz, G.A.. Comisión Nacional de Energía Atómica; Argentina
Fil: Ferrari, C.. University of Pavia; Italia
Materia
BNCT
CELL CYCLE
CELL SURVIVAL
RADIOBIOLOGICAL EFFECTS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/94609
Acceder
id CONICETDig_c8828ab28892f2f26e5769aecdcfc412
oai_identifier_str oai:ri.conicet.gov.ar:11336/94609
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatmentsCansolino, L.Clerici, A.M.Zonta, C.Dionigi, P.Mazzini, G.Di Liberto, R.Altieri, S.Ballarini, F.Bortolussi, S.Carante, M.P.Ferrari, M.González, Sara JosefinaPostuma, I.Protti, N.Santa Cruz, G.A.Ferrari, C.BNCTCELL CYCLECELL SURVIVALRADIOBIOLOGICAL EFFECTShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The present work is part of a preclinical in vitro study to assess the efficacy of BNCT applied to liver or lung coloncarcinoma metastases and to limb osteosarcoma. Adherent growing cell lines can be irradiated as adherent to the culture flasks or as cell suspensions, differences in radio-sensitivity of the two modalities of radiation exposure have been investigated. Dose related cell survival and cell cycle perturbation results evidenced that the radiosensitivity of adherent cells is higher than that of the suspended ones.Fil: Cansolino, L.. University of Pavia; Italia. Matteo Hospital; ItaliaFil: Clerici, A.M.. University of Pavia; ItaliaFil: Zonta, C.. University of Pavia; ItaliaFil: Dionigi, P.. University of Pavia; Italia. Matteo Hospital; ItaliaFil: Mazzini, G.. University of Pavia; ItaliaFil: Di Liberto, R.. Matteo Hospital; ItaliaFil: Altieri, S.. Istituto Nazionale Di Fisica Nucleare, Sezione Di Pavia; . Università Degli Studi Di Pavia; Fil: Ballarini, F.. University of Pavia; Italia. Istituto Nazionale Di Fisica Nucleare; ItaliaFil: Bortolussi, S.. Istituto Nazionale Di Fisica Nucleare; ItaliaFil: Carante, M.P.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; ItaliaFil: Ferrari, M.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; ItaliaFil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Postuma, I.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; ItaliaFil: Protti, N.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; ItaliaFil: Santa Cruz, G.A.. Comisión Nacional de Energía Atómica; ArgentinaFil: Ferrari, C.. University of Pavia; ItaliaPergamon-Elsevier Science Ltd2015-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/94609Cansolino, L.; Clerici, A.M.; Zonta, C.; Dionigi, P.; Mazzini, G.; et al.; Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 106; 12-2015; 226-2320969-8043CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804315301366info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.07.054info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-29T11:50:03Zoai:ri.conicet.gov.ar:11336/94609instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-29 11:50:03.455CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
title Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
spellingShingle Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
Cansolino, L.
BNCT
CELL CYCLE
CELL SURVIVAL
RADIOBIOLOGICAL EFFECTS
title_short Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
title_full Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
title_fullStr Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
title_full_unstemmed Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
title_sort Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments
dc.creator.none.fl_str_mv Cansolino, L.
Clerici, A.M.
Zonta, C.
Dionigi, P.
Mazzini, G.
Di Liberto, R.
Altieri, S.
Ballarini, F.
Bortolussi, S.
Carante, M.P.
Ferrari, M.
González, Sara Josefina
Postuma, I.
Protti, N.
Santa Cruz, G.A.
Ferrari, C.
author Cansolino, L.
author_facet Cansolino, L.
Clerici, A.M.
Zonta, C.
Dionigi, P.
Mazzini, G.
Di Liberto, R.
Altieri, S.
Ballarini, F.
Bortolussi, S.
Carante, M.P.
Ferrari, M.
González, Sara Josefina
Postuma, I.
Protti, N.
Santa Cruz, G.A.
Ferrari, C.
author_role author
author2 Clerici, A.M.
Zonta, C.
Dionigi, P.
Mazzini, G.
Di Liberto, R.
Altieri, S.
Ballarini, F.
Bortolussi, S.
Carante, M.P.
Ferrari, M.
González, Sara Josefina
Postuma, I.
Protti, N.
Santa Cruz, G.A.
Ferrari, C.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv BNCT
CELL CYCLE
CELL SURVIVAL
RADIOBIOLOGICAL EFFECTS
topic BNCT
CELL CYCLE
CELL SURVIVAL
RADIOBIOLOGICAL EFFECTS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The present work is part of a preclinical in vitro study to assess the efficacy of BNCT applied to liver or lung coloncarcinoma metastases and to limb osteosarcoma. Adherent growing cell lines can be irradiated as adherent to the culture flasks or as cell suspensions, differences in radio-sensitivity of the two modalities of radiation exposure have been investigated. Dose related cell survival and cell cycle perturbation results evidenced that the radiosensitivity of adherent cells is higher than that of the suspended ones.
Fil: Cansolino, L.. University of Pavia; Italia. Matteo Hospital; Italia
Fil: Clerici, A.M.. University of Pavia; Italia
Fil: Zonta, C.. University of Pavia; Italia
Fil: Dionigi, P.. University of Pavia; Italia. Matteo Hospital; Italia
Fil: Mazzini, G.. University of Pavia; Italia
Fil: Di Liberto, R.. Matteo Hospital; Italia
Fil: Altieri, S.. Istituto Nazionale Di Fisica Nucleare, Sezione Di Pavia; . Università Degli Studi Di Pavia;
Fil: Ballarini, F.. University of Pavia; Italia. Istituto Nazionale Di Fisica Nucleare; Italia
Fil: Bortolussi, S.. Istituto Nazionale Di Fisica Nucleare; Italia
Fil: Carante, M.P.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Ferrari, M.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Postuma, I.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Protti, N.. Istituto Nazionale Di Fisica Nucleare; Italia. University of Pavia; Italia
Fil: Santa Cruz, G.A.. Comisión Nacional de Energía Atómica; Argentina
Fil: Ferrari, C.. University of Pavia; Italia
description The present work is part of a preclinical in vitro study to assess the efficacy of BNCT applied to liver or lung coloncarcinoma metastases and to limb osteosarcoma. Adherent growing cell lines can be irradiated as adherent to the culture flasks or as cell suspensions, differences in radio-sensitivity of the two modalities of radiation exposure have been investigated. Dose related cell survival and cell cycle perturbation results evidenced that the radiosensitivity of adherent cells is higher than that of the suspended ones.
publishDate 2015
dc.date.none.fl_str_mv 2015-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/94609
Cansolino, L.; Clerici, A.M.; Zonta, C.; Dionigi, P.; Mazzini, G.; et al.; Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 106; 12-2015; 226-232
0969-8043
CONICET Digital
CONICET
url http://hdl.handle.net/11336/94609
identifier_str_mv Cansolino, L.; Clerici, A.M.; Zonta, C.; Dionigi, P.; Mazzini, G.; et al.; Comparative study of the radiobiological effects induced on adherent vs suspended cells by BNCT, neutrons and gamma rays treatments; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 106; 12-2015; 226-232
0969-8043
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804315301366
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.07.054
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1847426543101411328
score 13.10058

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