Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina

Autores
Gadan, M.A.; González, Sara Josefina; Batalla, M.; Olivera, M.S.; Policastro, Lucia Laura; Sztejnberg, M.L.
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the frame of the Argentine BNCT Project a new research line has been started to study the application of BNCT to the treatment of locoregional recurrences of HER2+ breast cancer subtype. Based on former studies, the strategy considers the use of immunoliposomes as boron carriers nanovehicles to target HER2 overexpressing cells. The essential concerns of the current stage of this proposal are the development of carriers that can improve the efficiency of delivery of boron compounds and the dosimetric assessment of treatment feasibility. For this purpose, an specific pool of clinical cases that can benefit from this application was determined. In this work, we present the proposal and the advances related to the different stages of current research.
Fil: Gadan, M.A.. Comisión Nacional de Energía Atómica; Argentina
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Batalla, M.. Comisión Nacional de Energía Atómica; Argentina
Fil: Olivera, M.S.. Comisión Nacional de Energía Atómica; Argentina
Fil: Policastro, Lucia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Sztejnberg, M.L.. Comisión Nacional de Energía Atómica; Argentina
Materia
HER2-ENRICHED BREAST CANCER
IMMUNOLIPOSOMES
POST TREATMENT RECURRENCES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/94607
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in ArgentinaGadan, M.A.González, Sara JosefinaBatalla, M.Olivera, M.S.Policastro, Lucia LauraSztejnberg, M.L.HER2-ENRICHED BREAST CANCERIMMUNOLIPOSOMESPOST TREATMENT RECURRENCEShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3In the frame of the Argentine BNCT Project a new research line has been started to study the application of BNCT to the treatment of locoregional recurrences of HER2+ breast cancer subtype. Based on former studies, the strategy considers the use of immunoliposomes as boron carriers nanovehicles to target HER2 overexpressing cells. The essential concerns of the current stage of this proposal are the development of carriers that can improve the efficiency of delivery of boron compounds and the dosimetric assessment of treatment feasibility. For this purpose, an specific pool of clinical cases that can benefit from this application was determined. In this work, we present the proposal and the advances related to the different stages of current research.Fil: Gadan, M.A.. Comisión Nacional de Energía Atómica; ArgentinaFil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Batalla, M.. Comisión Nacional de Energía Atómica; ArgentinaFil: Olivera, M.S.. Comisión Nacional de Energía Atómica; ArgentinaFil: Policastro, Lucia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Sztejnberg, M.L.. Comisión Nacional de Energía Atómica; ArgentinaPergamon-Elsevier Science Ltd2015-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/94607Gadan, M.A.; González, Sara Josefina; Batalla, M.; Olivera, M.S.; Policastro, Lucia Laura; et al.; Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 104; 10-2015; 155-1590969-8043CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804315300877info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.07.006info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:51:23Zoai:ri.conicet.gov.ar:11336/94607instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:51:23.757CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
title Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
spellingShingle Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
Gadan, M.A.
HER2-ENRICHED BREAST CANCER
IMMUNOLIPOSOMES
POST TREATMENT RECURRENCES
title_short Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
title_full Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
title_fullStr Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
title_full_unstemmed Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
title_sort Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina
dc.creator.none.fl_str_mv Gadan, M.A.
González, Sara Josefina
Batalla, M.
Olivera, M.S.
Policastro, Lucia Laura
Sztejnberg, M.L.
author Gadan, M.A.
author_facet Gadan, M.A.
González, Sara Josefina
Batalla, M.
Olivera, M.S.
Policastro, Lucia Laura
Sztejnberg, M.L.
author_role author
author2 González, Sara Josefina
Batalla, M.
Olivera, M.S.
Policastro, Lucia Laura
Sztejnberg, M.L.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv HER2-ENRICHED BREAST CANCER
IMMUNOLIPOSOMES
POST TREATMENT RECURRENCES
topic HER2-ENRICHED BREAST CANCER
IMMUNOLIPOSOMES
POST TREATMENT RECURRENCES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In the frame of the Argentine BNCT Project a new research line has been started to study the application of BNCT to the treatment of locoregional recurrences of HER2+ breast cancer subtype. Based on former studies, the strategy considers the use of immunoliposomes as boron carriers nanovehicles to target HER2 overexpressing cells. The essential concerns of the current stage of this proposal are the development of carriers that can improve the efficiency of delivery of boron compounds and the dosimetric assessment of treatment feasibility. For this purpose, an specific pool of clinical cases that can benefit from this application was determined. In this work, we present the proposal and the advances related to the different stages of current research.
Fil: Gadan, M.A.. Comisión Nacional de Energía Atómica; Argentina
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Batalla, M.. Comisión Nacional de Energía Atómica; Argentina
Fil: Olivera, M.S.. Comisión Nacional de Energía Atómica; Argentina
Fil: Policastro, Lucia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Sztejnberg, M.L.. Comisión Nacional de Energía Atómica; Argentina
description In the frame of the Argentine BNCT Project a new research line has been started to study the application of BNCT to the treatment of locoregional recurrences of HER2+ breast cancer subtype. Based on former studies, the strategy considers the use of immunoliposomes as boron carriers nanovehicles to target HER2 overexpressing cells. The essential concerns of the current stage of this proposal are the development of carriers that can improve the efficiency of delivery of boron compounds and the dosimetric assessment of treatment feasibility. For this purpose, an specific pool of clinical cases that can benefit from this application was determined. In this work, we present the proposal and the advances related to the different stages of current research.
publishDate 2015
dc.date.none.fl_str_mv 2015-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/94607
Gadan, M.A.; González, Sara Josefina; Batalla, M.; Olivera, M.S.; Policastro, Lucia Laura; et al.; Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 104; 10-2015; 155-159
0969-8043
CONICET Digital
CONICET
url http://hdl.handle.net/11336/94607
identifier_str_mv Gadan, M.A.; González, Sara Josefina; Batalla, M.; Olivera, M.S.; Policastro, Lucia Laura; et al.; Application of BNCT to the treatment of HER2+ breast cancer recurrences: Research and developments in Argentina; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 104; 10-2015; 155-159
0969-8043
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804315300877
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2015.07.006
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613580446498816
score 13.070432

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