Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina

Autores
Pavicich, Maria Agustina; De Boevre, Marthe; Vidal, Arnau; Mikula, Hannes; Warth, Benedikt; Marko, Doris; De Saeger, Sarah; Patriarca, Andrea Rosana
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Data on the natural occurrence of Alternaria mycotoxins in apple by-products is lacking in Argentina and the risk of exposure to these mycotoxins has not been characterized before. The levels of alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), tenuazonic acid (TeA), tentoxin (TEN), altertoxin-I (ATX-I), altertoxin-II (ATX-II), alternariol 3-sulfate (AOH-3-S), alternariol 3-glucoside (AOH-3-G), alternariol monomethyl ether 3-sulfate (AME-3-S), and alternariol monomethyl ether 3-glucoside (AME-3-G) were determined in clarifed and cloudy apple juices, marmalades, and applebased infant food from the Argentinean market, and the risk of exposure was characterized. Detectable levels of AME, TEN, TeA, AME-3-S and AOH-3-G were found in clarifed juices, while the same mycotoxins plus AOH were found in cloudy apple juices in higher concentrations. AME, TEN, TeA and AOH-3G were detected in marmalades, and AOH, AME, TEN and TeA in apple infant food. Probabilistic exposure assessment and risk characterization were carried out for children between 6 months and 5 years old in Argentina. The highest risk of exposure afected children between 6 and 23 months from the consumption of apple infant food and mainly associated with the alternariols. Better control strategies to prevent the incorporation of Alternaria mouldy core into the process line and the establishment of legislation for Alternaria mycotoxins are needed in Argentina.
Fil: Pavicich, Maria Agustina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; Argentina
Fil: De Boevre, Marthe. University of Ghent; Bélgica
Fil: Vidal, Arnau. University of Ghent; Bélgica
Fil: Mikula, Hannes. Graz University Of Technology.; Austria
Fil: Warth, Benedikt. Vienna University of Technology; Austria
Fil: Marko, Doris. Vienna University of Technology; Austria
Fil: De Saeger, Sarah. University of Ghent; Bélgica
Fil: Patriarca, Andrea Rosana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; Argentina
Materia
INFANT FOODS
CONSUMER'S RISK
MODIFIED MYCOTOXINS
ALTERNARIOL
FOOD SAFETY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/239969
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/239969
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in ArgentinaPavicich, Maria AgustinaDe Boevre, MartheVidal, ArnauMikula, HannesWarth, BenediktMarko, DorisDe Saeger, SarahPatriarca, Andrea RosanaINFANT FOODSCONSUMER'S RISKMODIFIED MYCOTOXINSALTERNARIOLFOOD SAFETYhttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Data on the natural occurrence of Alternaria mycotoxins in apple by-products is lacking in Argentina and the risk of exposure to these mycotoxins has not been characterized before. The levels of alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), tenuazonic acid (TeA), tentoxin (TEN), altertoxin-I (ATX-I), altertoxin-II (ATX-II), alternariol 3-sulfate (AOH-3-S), alternariol 3-glucoside (AOH-3-G), alternariol monomethyl ether 3-sulfate (AME-3-S), and alternariol monomethyl ether 3-glucoside (AME-3-G) were determined in clarifed and cloudy apple juices, marmalades, and applebased infant food from the Argentinean market, and the risk of exposure was characterized. Detectable levels of AME, TEN, TeA, AME-3-S and AOH-3-G were found in clarifed juices, while the same mycotoxins plus AOH were found in cloudy apple juices in higher concentrations. AME, TEN, TeA and AOH-3G were detected in marmalades, and AOH, AME, TEN and TeA in apple infant food. Probabilistic exposure assessment and risk characterization were carried out for children between 6 months and 5 years old in Argentina. The highest risk of exposure afected children between 6 and 23 months from the consumption of apple infant food and mainly associated with the alternariols. Better control strategies to prevent the incorporation of Alternaria mouldy core into the process line and the establishment of legislation for Alternaria mycotoxins are needed in Argentina.Fil: Pavicich, Maria Agustina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; ArgentinaFil: De Boevre, Marthe. University of Ghent; BélgicaFil: Vidal, Arnau. University of Ghent; BélgicaFil: Mikula, Hannes. Graz University Of Technology.; AustriaFil: Warth, Benedikt. Vienna University of Technology; AustriaFil: Marko, Doris. Vienna University of Technology; AustriaFil: De Saeger, Sarah. University of Ghent; BélgicaFil: Patriarca, Andrea Rosana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; ArgentinaSpringer2023-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/239969Pavicich, Maria Agustina; De Boevre, Marthe; Vidal, Arnau; Mikula, Hannes; Warth, Benedikt; et al.; Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina; Springer; Exposure and Health; 16; 1; 4-2023; 149-1582451-97662451-9685CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s12403-023-00544-1info:eu-repo/semantics/altIdentifier/doi/10.1007/s12403-023-00544-1info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:10:08Zoai:ri.conicet.gov.ar:11336/239969instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:10:09.223CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
title Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
spellingShingle Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
Pavicich, Maria Agustina
INFANT FOODS
CONSUMER'S RISK
MODIFIED MYCOTOXINS
ALTERNARIOL
FOOD SAFETY
title_short Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
title_full Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
title_fullStr Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
title_full_unstemmed Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
title_sort Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina
dc.creator.none.fl_str_mv Pavicich, Maria Agustina
De Boevre, Marthe
Vidal, Arnau
Mikula, Hannes
Warth, Benedikt
Marko, Doris
De Saeger, Sarah
Patriarca, Andrea Rosana
author Pavicich, Maria Agustina
author_facet Pavicich, Maria Agustina
De Boevre, Marthe
Vidal, Arnau
Mikula, Hannes
Warth, Benedikt
Marko, Doris
De Saeger, Sarah
Patriarca, Andrea Rosana
author_role author
author2 De Boevre, Marthe
Vidal, Arnau
Mikula, Hannes
Warth, Benedikt
Marko, Doris
De Saeger, Sarah
Patriarca, Andrea Rosana
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv INFANT FOODS
CONSUMER'S RISK
MODIFIED MYCOTOXINS
ALTERNARIOL
FOOD SAFETY
topic INFANT FOODS
CONSUMER'S RISK
MODIFIED MYCOTOXINS
ALTERNARIOL
FOOD SAFETY
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Data on the natural occurrence of Alternaria mycotoxins in apple by-products is lacking in Argentina and the risk of exposure to these mycotoxins has not been characterized before. The levels of alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), tenuazonic acid (TeA), tentoxin (TEN), altertoxin-I (ATX-I), altertoxin-II (ATX-II), alternariol 3-sulfate (AOH-3-S), alternariol 3-glucoside (AOH-3-G), alternariol monomethyl ether 3-sulfate (AME-3-S), and alternariol monomethyl ether 3-glucoside (AME-3-G) were determined in clarifed and cloudy apple juices, marmalades, and applebased infant food from the Argentinean market, and the risk of exposure was characterized. Detectable levels of AME, TEN, TeA, AME-3-S and AOH-3-G were found in clarifed juices, while the same mycotoxins plus AOH were found in cloudy apple juices in higher concentrations. AME, TEN, TeA and AOH-3G were detected in marmalades, and AOH, AME, TEN and TeA in apple infant food. Probabilistic exposure assessment and risk characterization were carried out for children between 6 months and 5 years old in Argentina. The highest risk of exposure afected children between 6 and 23 months from the consumption of apple infant food and mainly associated with the alternariols. Better control strategies to prevent the incorporation of Alternaria mouldy core into the process line and the establishment of legislation for Alternaria mycotoxins are needed in Argentina.
Fil: Pavicich, Maria Agustina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; Argentina
Fil: De Boevre, Marthe. University of Ghent; Bélgica
Fil: Vidal, Arnau. University of Ghent; Bélgica
Fil: Mikula, Hannes. Graz University Of Technology.; Austria
Fil: Warth, Benedikt. Vienna University of Technology; Austria
Fil: Marko, Doris. Vienna University of Technology; Austria
Fil: De Saeger, Sarah. University of Ghent; Bélgica
Fil: Patriarca, Andrea Rosana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Micología y Botánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Micología y Botánica; Argentina
description Data on the natural occurrence of Alternaria mycotoxins in apple by-products is lacking in Argentina and the risk of exposure to these mycotoxins has not been characterized before. The levels of alternariol (AOH), alternariol monomethyl ether (AME), altenuene (ALT), tenuazonic acid (TeA), tentoxin (TEN), altertoxin-I (ATX-I), altertoxin-II (ATX-II), alternariol 3-sulfate (AOH-3-S), alternariol 3-glucoside (AOH-3-G), alternariol monomethyl ether 3-sulfate (AME-3-S), and alternariol monomethyl ether 3-glucoside (AME-3-G) were determined in clarifed and cloudy apple juices, marmalades, and applebased infant food from the Argentinean market, and the risk of exposure was characterized. Detectable levels of AME, TEN, TeA, AME-3-S and AOH-3-G were found in clarifed juices, while the same mycotoxins plus AOH were found in cloudy apple juices in higher concentrations. AME, TEN, TeA and AOH-3G were detected in marmalades, and AOH, AME, TEN and TeA in apple infant food. Probabilistic exposure assessment and risk characterization were carried out for children between 6 months and 5 years old in Argentina. The highest risk of exposure afected children between 6 and 23 months from the consumption of apple infant food and mainly associated with the alternariols. Better control strategies to prevent the incorporation of Alternaria mouldy core into the process line and the establishment of legislation for Alternaria mycotoxins are needed in Argentina.
publishDate 2023
dc.date.none.fl_str_mv 2023-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/239969
Pavicich, Maria Agustina; De Boevre, Marthe; Vidal, Arnau; Mikula, Hannes; Warth, Benedikt; et al.; Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina; Springer; Exposure and Health; 16; 1; 4-2023; 149-158
2451-9766
2451-9685
CONICET Digital
CONICET
url http://hdl.handle.net/11336/239969
identifier_str_mv Pavicich, Maria Agustina; De Boevre, Marthe; Vidal, Arnau; Mikula, Hannes; Warth, Benedikt; et al.; Natural Occurrence, Exposure Assessment & Risk Characterization of Alternaria Mycotoxins in Apple By-Products in Argentina; Springer; Exposure and Health; 16; 1; 4-2023; 149-158
2451-9766
2451-9685
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s12403-023-00544-1
info:eu-repo/semantics/altIdentifier/doi/10.1007/s12403-023-00544-1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.885934

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