The hypophysis and secretion of insulin

Autores
Houssay, Bernardo Alberto; Foglia, Virgilio G.; Smyth, F. S.; Rietti, Ciro T.; Houssay, Alberto B.
Año de publicación
1942
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic action of insulin and other hypoglycemie agents such as phloridzin, fasting, etc. (2) Reduction of intensity of pancreatic and phloridzin diabetes. (3) A rapid fall in blood sugar and tissue glycogen during fasting; of non-pancreatic origin since it occurs after pancreatectomy. The hypoglycemic symptoms can be relieved by prompt administration of glucose, or prevented by a carbohydrate or protein, but not fat diet.
Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; Argentina
Fil: Foglia, Virgilio G.. Universidad de Buenos Aires; Argentina
Fil: Smyth, F. S.. Universidad de Buenos Aires; Argentina
Fil: Rietti, Ciro T.. Universidad de Buenos Aires; Argentina
Fil: Houssay, Alberto B.. Universidad de Buenos Aires; Argentina
fondo
Materia
HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
DIABETES
PANCREATIC SECRETION
HYPOPHYSECTOMY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/125031
Acceder
id CONICETDig_c362ce28390f4110d8fa5dadd15f90c9
oai_identifier_str oai:ri.conicet.gov.ar:11336/125031
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The hypophysis and secretion of insulinHoussay, Bernardo AlbertoFoglia, Virgilio G.Smyth, F. S.Rietti, Ciro T.Houssay, Alberto B.HOUSSAY, BERNARDO ALBERTOEL INVESTIGADORHOUSSAY EL INVESTIGADORPUBLICACIONESDIABETESPANCREATIC SECRETIONHYPOPHYSECTOMYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/6.3https://purl.org/becyt/ford/6The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic action of insulin and other hypoglycemie agents such as phloridzin, fasting, etc. (2) Reduction of intensity of pancreatic and phloridzin diabetes. (3) A rapid fall in blood sugar and tissue glycogen during fasting; of non-pancreatic origin since it occurs after pancreatectomy. The hypoglycemic symptoms can be relieved by prompt administration of glucose, or prevented by a carbohydrate or protein, but not fat diet.Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; ArgentinaFil: Foglia, Virgilio G.. Universidad de Buenos Aires; ArgentinaFil: Smyth, F. S.. Universidad de Buenos Aires; ArgentinaFil: Rietti, Ciro T.. Universidad de Buenos Aires; ArgentinaFil: Houssay, Alberto B.. Universidad de Buenos Aires; ArgentinafondoThe Rockefeller University Press1942-01-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulotext/plainBlancoNegroSiapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/125031Houssay, Bernardo Alberto; Foglia, Virgilio G.; Smyth, F. S.; Rietti, Ciro T.; Houssay, Alberto B.; The hypophysis and secretion of insulin; The Rockefeller University Press; Journal of Experimental Medicine; 75; 5; 5-1-1942; 547-5660022-1007enginfo:eu-repo/semantics/altIdentifier/doi/10.1084/jem.75.5.547info:eu-repo/semantics/altIdentifier/url/https://rupress.org/jem/article/75/5/547/4616/THE-HYPOPHYSIS-AND-SECRETION-OF-INSULINCiudad de Buenos AiresFundacion Williams.Fundación de Instituto de Biología y Medicina ExperimentalConsejo Nacional de Investigaciones Científicas y TécnicasProyecto Houssay y Leloirinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:17:00Zoai:ri.conicet.gov.ar:11336/125031instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:17:00.622CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The hypophysis and secretion of insulin
title The hypophysis and secretion of insulin
spellingShingle The hypophysis and secretion of insulin
Houssay, Bernardo Alberto
HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
DIABETES
PANCREATIC SECRETION
HYPOPHYSECTOMY
title_short The hypophysis and secretion of insulin
title_full The hypophysis and secretion of insulin
title_fullStr The hypophysis and secretion of insulin
title_full_unstemmed The hypophysis and secretion of insulin
title_sort The hypophysis and secretion of insulin
dc.creator.none.fl_str_mv Houssay, Bernardo Alberto
Foglia, Virgilio G.
Smyth, F. S.
Rietti, Ciro T.
Houssay, Alberto B.
author Houssay, Bernardo Alberto
author_facet Houssay, Bernardo Alberto
Foglia, Virgilio G.
Smyth, F. S.
Rietti, Ciro T.
Houssay, Alberto B.
author_role author
author2 Foglia, Virgilio G.
Smyth, F. S.
Rietti, Ciro T.
Houssay, Alberto B.
author2_role author
author
author
author
dc.subject.none.fl_str_mv HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
DIABETES
PANCREATIC SECRETION
HYPOPHYSECTOMY
topic HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
DIABETES
PANCREATIC SECRETION
HYPOPHYSECTOMY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/6.3
https://purl.org/becyt/ford/6
dc.description.none.fl_txt_mv The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic action of insulin and other hypoglycemie agents such as phloridzin, fasting, etc. (2) Reduction of intensity of pancreatic and phloridzin diabetes. (3) A rapid fall in blood sugar and tissue glycogen during fasting; of non-pancreatic origin since it occurs after pancreatectomy. The hypoglycemic symptoms can be relieved by prompt administration of glucose, or prevented by a carbohydrate or protein, but not fat diet.
Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; Argentina
Fil: Foglia, Virgilio G.. Universidad de Buenos Aires; Argentina
Fil: Smyth, F. S.. Universidad de Buenos Aires; Argentina
Fil: Rietti, Ciro T.. Universidad de Buenos Aires; Argentina
Fil: Houssay, Alberto B.. Universidad de Buenos Aires; Argentina
fondo
description The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) lobe removal produces: (1) Marked sensitivity to the hypoglycemic and toxic action of insulin and other hypoglycemie agents such as phloridzin, fasting, etc. (2) Reduction of intensity of pancreatic and phloridzin diabetes. (3) A rapid fall in blood sugar and tissue glycogen during fasting; of non-pancreatic origin since it occurs after pancreatectomy. The hypoglycemic symptoms can be relieved by prompt administration of glucose, or prevented by a carbohydrate or protein, but not fat diet.
publishDate 1942
dc.date.none.fl_str_mv 1942-01-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/125031
Houssay, Bernardo Alberto; Foglia, Virgilio G.; Smyth, F. S.; Rietti, Ciro T.; Houssay, Alberto B.; The hypophysis and secretion of insulin; The Rockefeller University Press; Journal of Experimental Medicine; 75; 5; 5-1-1942; 547-566
0022-1007
url http://hdl.handle.net/11336/125031
identifier_str_mv Houssay, Bernardo Alberto; Foglia, Virgilio G.; Smyth, F. S.; Rietti, Ciro T.; Houssay, Alberto B.; The hypophysis and secretion of insulin; The Rockefeller University Press; Journal of Experimental Medicine; 75; 5; 5-1-1942; 547-566
0022-1007
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1084/jem.75.5.547
info:eu-repo/semantics/altIdentifier/url/https://rupress.org/jem/article/75/5/547/4616/THE-HYPOPHYSIS-AND-SECRETION-OF-INSULIN
Ciudad de Buenos Aires
Fundacion Williams.
Fundación de Instituto de Biología y Medicina Experimental
Consejo Nacional de Investigaciones Científicas y Técnicas
Proyecto Houssay y Leloir
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv text/plain
BlancoNegro
Si
application/pdf
application/pdf
dc.publisher.none.fl_str_mv The Rockefeller University Press
publisher.none.fl_str_mv The Rockefeller University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614119187021824
score 13.070432

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