The discovery of pancreatic diabetes: the role of Oscar Minkowski

Autores
Houssay, Bernardo A.
Año de publicación
1952
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In 1889 von Mering and Minkowski reported that total pancreatectomy in dogs was followed by severe diabetes. This was a discovery of historic importance. It demonstrated that diabetes occurs in the absence of the pancreas; and this finding furnished the starting point for research which proved that this organ produces an internal secretion, thus leading to the discovery of insulin and its application to the treatment of patients suffering from diabetes. Studies on carbohydrate metabolism were considerably extended, and it became possible to demonstrate the role of the liver in this metabolism and the regulatory functions of hormones secreted by several endocrine glands in normal conditions and in diabetes.
Fil: Houssay, Bernardo A.. Fundación de Instituto de Biología y Medicina Experimental; Argentina
papel
Publicaciones científicas
Unidad documental simple
Materia
HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
HISTORIA DE LA MEDICINA
DIABETES
MINKOWSKY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/156700
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/156700
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The discovery of pancreatic diabetes: the role of Oscar MinkowskiHoussay, Bernardo A.HOUSSAY, BERNARDO ALBERTOEL INVESTIGADORHOUSSAY EL INVESTIGADORPUBLICACIONES CIENTIFICASPUBLICACIONESHISTORIA DE LA MEDICINADIABETESMINKOWSKYhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/6.3https://purl.org/becyt/ford/6In 1889 von Mering and Minkowski reported that total pancreatectomy in dogs was followed by severe diabetes. This was a discovery of historic importance. It demonstrated that diabetes occurs in the absence of the pancreas; and this finding furnished the starting point for research which proved that this organ produces an internal secretion, thus leading to the discovery of insulin and its application to the treatment of patients suffering from diabetes. Studies on carbohydrate metabolism were considerably extended, and it became possible to demonstrate the role of the liver in this metabolism and the regulatory functions of hormones secreted by several endocrine glands in normal conditions and in diabetes.Fil: Houssay, Bernardo A.. Fundación de Instituto de Biología y Medicina Experimental; ArgentinapapelPublicaciones científicasUnidad documental simpleAmerican Diabetes Association1952info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulotext/plainBlancoNegroSiapplication/pdfhttp://hdl.handle.net/11336/156700Houssay, Bernardo A.; The discovery of pancreatic diabetes: the role of Oscar Minkowski; American Diabetes Association; Diabetes; 1; 2; 1952; 112-1160012-1797enginfo:eu-repo/semantics/reference/url/https://link.springer.com/chapter/10.1007/978-3-642-48364-6_24info:eu-repo/semantics/altIdentifier/url/https://diabetes.diabetesjournals.org/content/1/2/112info:eu-repo/semantics/altIdentifier/doi/10.2337/diab.1.2.112Ciudad de Buenos AiresFundación de Instituto de Biología y Medicina ExperimentalFundacion Williams.Consejo Nacional de Investigaciones Científicas y TécnicasProyecto Houssay y LeloirIBYMEAR02675-ACder-0338finfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T10:41:50Zoai:ri.conicet.gov.ar:11336/156700instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 10:41:51.235CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The discovery of pancreatic diabetes: the role of Oscar Minkowski
title The discovery of pancreatic diabetes: the role of Oscar Minkowski
spellingShingle The discovery of pancreatic diabetes: the role of Oscar Minkowski
Houssay, Bernardo A.
HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
HISTORIA DE LA MEDICINA
DIABETES
MINKOWSKY
title_short The discovery of pancreatic diabetes: the role of Oscar Minkowski
title_full The discovery of pancreatic diabetes: the role of Oscar Minkowski
title_fullStr The discovery of pancreatic diabetes: the role of Oscar Minkowski
title_full_unstemmed The discovery of pancreatic diabetes: the role of Oscar Minkowski
title_sort The discovery of pancreatic diabetes: the role of Oscar Minkowski
dc.creator.none.fl_str_mv Houssay, Bernardo A.
author Houssay, Bernardo A.
author_facet Houssay, Bernardo A.
author_role author
dc.subject.none.fl_str_mv HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
HISTORIA DE LA MEDICINA
DIABETES
MINKOWSKY
topic HOUSSAY, BERNARDO ALBERTO
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
HISTORIA DE LA MEDICINA
DIABETES
MINKOWSKY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/6.3
https://purl.org/becyt/ford/6
dc.description.none.fl_txt_mv In 1889 von Mering and Minkowski reported that total pancreatectomy in dogs was followed by severe diabetes. This was a discovery of historic importance. It demonstrated that diabetes occurs in the absence of the pancreas; and this finding furnished the starting point for research which proved that this organ produces an internal secretion, thus leading to the discovery of insulin and its application to the treatment of patients suffering from diabetes. Studies on carbohydrate metabolism were considerably extended, and it became possible to demonstrate the role of the liver in this metabolism and the regulatory functions of hormones secreted by several endocrine glands in normal conditions and in diabetes.
Fil: Houssay, Bernardo A.. Fundación de Instituto de Biología y Medicina Experimental; Argentina
papel
Publicaciones científicas
Unidad documental simple
description In 1889 von Mering and Minkowski reported that total pancreatectomy in dogs was followed by severe diabetes. This was a discovery of historic importance. It demonstrated that diabetes occurs in the absence of the pancreas; and this finding furnished the starting point for research which proved that this organ produces an internal secretion, thus leading to the discovery of insulin and its application to the treatment of patients suffering from diabetes. Studies on carbohydrate metabolism were considerably extended, and it became possible to demonstrate the role of the liver in this metabolism and the regulatory functions of hormones secreted by several endocrine glands in normal conditions and in diabetes.
publishDate 1952
dc.date.none.fl_str_mv 1952
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/156700
Houssay, Bernardo A.; The discovery of pancreatic diabetes: the role of Oscar Minkowski; American Diabetes Association; Diabetes; 1; 2; 1952; 112-116
0012-1797
url http://hdl.handle.net/11336/156700
identifier_str_mv Houssay, Bernardo A.; The discovery of pancreatic diabetes: the role of Oscar Minkowski; American Diabetes Association; Diabetes; 1; 2; 1952; 112-116
0012-1797
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/reference/url/https://link.springer.com/chapter/10.1007/978-3-642-48364-6_24
info:eu-repo/semantics/altIdentifier/url/https://diabetes.diabetesjournals.org/content/1/2/112
info:eu-repo/semantics/altIdentifier/doi/10.2337/diab.1.2.112
Ciudad de Buenos Aires
Fundación de Instituto de Biología y Medicina Experimental
Fundacion Williams.
Consejo Nacional de Investigaciones Científicas y Técnicas
Proyecto Houssay y Leloir
IBYME
AR02675-ACder-0338f
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv text/plain
BlancoNegro
Si
application/pdf
dc.publisher.none.fl_str_mv American Diabetes Association
publisher.none.fl_str_mv American Diabetes Association
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1843605873650302976
score 13.001348

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