Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS

Autores
Mariño Repizo, Leonardo; Goicoechea, Hector Casimiro; Raba, Julio; Cerutti, Estela Soledad
Año de publicación
2017
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Ochratoxin A (OTA) is a toxic compound, initiator, promoter of cancers and endemic diseases1. OTA contamination might occur when the ochratoxigenic fungi infect the cereal crops (mostly barley and wheat), during their cultivation and until post-harvest2. Thus, beer might contain OTA traces since brewing, cereals (malt) might be contaminated3. Therefore, some countries have established maximum allowable limits (MALs) to reduce OTA intake from beer (0.2 µg/L)4. For that reason, simple, effective and sensitive methods for OTA determination at low concentration levels are necessary5. Hence, a novel sample treatment methodology based on salting-out assisted liquid-liquid extraction (SALLE) was optimized using a multivariate design of experiments strategy and, then coupled to ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
Fil: Mariño Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina
Fil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
VIII Workshop de Quimiometria
Salvador
Brasil
Grupo de Pesquisa em Química e Quimiometria
Materia
OCHRATOXIN
BEER
SALLE-BASED APPROACH
UHPLC-MS/MS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/277137
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MSMariño Repizo, LeonardoGoicoechea, Hector CasimiroRaba, JulioCerutti, Estela SoledadOCHRATOXINBEERSALLE-BASED APPROACHUHPLC-MS/MShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Ochratoxin A (OTA) is a toxic compound, initiator, promoter of cancers and endemic diseases1. OTA contamination might occur when the ochratoxigenic fungi infect the cereal crops (mostly barley and wheat), during their cultivation and until post-harvest2. Thus, beer might contain OTA traces since brewing, cereals (malt) might be contaminated3. Therefore, some countries have established maximum allowable limits (MALs) to reduce OTA intake from beer (0.2 µg/L)4. For that reason, simple, effective and sensitive methods for OTA determination at low concentration levels are necessary5. Hence, a novel sample treatment methodology based on salting-out assisted liquid-liquid extraction (SALLE) was optimized using a multivariate design of experiments strategy and, then coupled to ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).Fil: Mariño Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; ArgentinaFil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaVIII Workshop de QuimiometriaSalvadorBrasilGrupo de Pesquisa em Química e QuimiometriaGrupo de Pesquisa em Química e Quimiometria2017info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectWorkshopBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/277137Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS; VIII Workshop de Quimiometria; Salvador; Brasil; 2017; 1-6978-85-8140-103-4CONICET DigitalCONICETengInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-12-23T14:28:44Zoai:ri.conicet.gov.ar:11336/277137instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-12-23 14:28:45.124CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
title Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
spellingShingle Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
Mariño Repizo, Leonardo
OCHRATOXIN
BEER
SALLE-BASED APPROACH
UHPLC-MS/MS
title_short Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
title_full Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
title_fullStr Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
title_full_unstemmed Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
title_sort Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS
dc.creator.none.fl_str_mv Mariño Repizo, Leonardo
Goicoechea, Hector Casimiro
Raba, Julio
Cerutti, Estela Soledad
author Mariño Repizo, Leonardo
author_facet Mariño Repizo, Leonardo
Goicoechea, Hector Casimiro
Raba, Julio
Cerutti, Estela Soledad
author_role author
author2 Goicoechea, Hector Casimiro
Raba, Julio
Cerutti, Estela Soledad
author2_role author
author
author
dc.subject.none.fl_str_mv OCHRATOXIN
BEER
SALLE-BASED APPROACH
UHPLC-MS/MS
topic OCHRATOXIN
BEER
SALLE-BASED APPROACH
UHPLC-MS/MS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Ochratoxin A (OTA) is a toxic compound, initiator, promoter of cancers and endemic diseases1. OTA contamination might occur when the ochratoxigenic fungi infect the cereal crops (mostly barley and wheat), during their cultivation and until post-harvest2. Thus, beer might contain OTA traces since brewing, cereals (malt) might be contaminated3. Therefore, some countries have established maximum allowable limits (MALs) to reduce OTA intake from beer (0.2 µg/L)4. For that reason, simple, effective and sensitive methods for OTA determination at low concentration levels are necessary5. Hence, a novel sample treatment methodology based on salting-out assisted liquid-liquid extraction (SALLE) was optimized using a multivariate design of experiments strategy and, then coupled to ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
Fil: Mariño Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina
Fil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
VIII Workshop de Quimiometria
Salvador
Brasil
Grupo de Pesquisa em Química e Quimiometria
description Ochratoxin A (OTA) is a toxic compound, initiator, promoter of cancers and endemic diseases1. OTA contamination might occur when the ochratoxigenic fungi infect the cereal crops (mostly barley and wheat), during their cultivation and until post-harvest2. Thus, beer might contain OTA traces since brewing, cereals (malt) might be contaminated3. Therefore, some countries have established maximum allowable limits (MALs) to reduce OTA intake from beer (0.2 µg/L)4. For that reason, simple, effective and sensitive methods for OTA determination at low concentration levels are necessary5. Hence, a novel sample treatment methodology based on salting-out assisted liquid-liquid extraction (SALLE) was optimized using a multivariate design of experiments strategy and, then coupled to ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Workshop
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/277137
Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS; VIII Workshop de Quimiometria; Salvador; Brasil; 2017; 1-6
978-85-8140-103-4
CONICET Digital
CONICET
url http://hdl.handle.net/11336/277137
identifier_str_mv Determination of Ochratoxin A in beer samples by a novel and practical SALLE-based approach prior to UHPLC-MS/MS; VIII Workshop de Quimiometria; Salvador; Brasil; 2017; 1-6
978-85-8140-103-4
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Grupo de Pesquisa em Química e Quimiometria
publisher.none.fl_str_mv Grupo de Pesquisa em Química e Quimiometria
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.952241

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