Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods

Autores
Chatgiglialoglu, Chryssostomos; Barata Vallejo, Sebastian; Giminis, Thanasis
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Radical reactions in water or aqueous media are important for organic synthesis, realizing high-yielding processes under non-toxic and environmentally friendly conditions. This overview includes (i) a general introduction to organic chemistry in water and aqueous media, (ii) synthetic approaches in, on, and with water as well as in heterogeneous phases, (iii) reactions of carbon-centered radicals with water (or deuterium oxide) activated through coordination with various Lewis acids, (iv) photocatalysis in water and aqueous media, and (v) synthetic applications bioinspired by naturally occurring processes. A wide range of chemical processes and synthetic strategies under different experimental conditions have been reviewed that lead to important functional group translocation and transformation reactions, leading to the preparation of complex molecules. These results reveal how water as a solvent/medium/reagent in radical chemistry has matured over the last two decades, with further discoveries anticipated in the near future.
Fil: Chatgiglialoglu, Chryssostomos. Consiglio Nazionale delle Ricerche; Italia
Fil: Barata Vallejo, Sebastian. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica. Cátedra de Química Orgánica I; Argentina. Consiglio Nazionale delle Ricerche; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Giminis, Thanasis. Universidad Nacional y Kapodistriaca de Atenas; Grecia
Materia
organic synthesis
radical reactions
water and aqueous media
bioinspired reactions
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/235436
Acceder
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spelling Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water MethodsChatgiglialoglu, ChryssostomosBarata Vallejo, SebastianGiminis, Thanasisorganic synthesisradical reactionswater and aqueous mediabioinspired reactionshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Radical reactions in water or aqueous media are important for organic synthesis, realizing high-yielding processes under non-toxic and environmentally friendly conditions. This overview includes (i) a general introduction to organic chemistry in water and aqueous media, (ii) synthetic approaches in, on, and with water as well as in heterogeneous phases, (iii) reactions of carbon-centered radicals with water (or deuterium oxide) activated through coordination with various Lewis acids, (iv) photocatalysis in water and aqueous media, and (v) synthetic applications bioinspired by naturally occurring processes. A wide range of chemical processes and synthetic strategies under different experimental conditions have been reviewed that lead to important functional group translocation and transformation reactions, leading to the preparation of complex molecules. These results reveal how water as a solvent/medium/reagent in radical chemistry has matured over the last two decades, with further discoveries anticipated in the near future.Fil: Chatgiglialoglu, Chryssostomos. Consiglio Nazionale delle Ricerche; ItaliaFil: Barata Vallejo, Sebastian. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica. Cátedra de Química Orgánica I; Argentina. Consiglio Nazionale delle Ricerche; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Giminis, Thanasis. Universidad Nacional y Kapodistriaca de Atenas; GreciaMolecular Diversity Preservation International2024-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/235436Chatgiglialoglu, Chryssostomos; Barata Vallejo, Sebastian; Giminis, Thanasis; Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods; Molecular Diversity Preservation International; Molecules; 29; 3; 1-2024; 1-511420-3049CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/molecules29030569info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:42:42Zoai:ri.conicet.gov.ar:11336/235436instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:42:43.052CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
title Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
spellingShingle Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
Chatgiglialoglu, Chryssostomos
organic synthesis
radical reactions
water and aqueous media
bioinspired reactions
title_short Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
title_full Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
title_fullStr Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
title_full_unstemmed Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
title_sort Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods
dc.creator.none.fl_str_mv Chatgiglialoglu, Chryssostomos
Barata Vallejo, Sebastian
Giminis, Thanasis
author Chatgiglialoglu, Chryssostomos
author_facet Chatgiglialoglu, Chryssostomos
Barata Vallejo, Sebastian
Giminis, Thanasis
author_role author
author2 Barata Vallejo, Sebastian
Giminis, Thanasis
author2_role author
author
dc.subject.none.fl_str_mv organic synthesis
radical reactions
water and aqueous media
bioinspired reactions
topic organic synthesis
radical reactions
water and aqueous media
bioinspired reactions
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Radical reactions in water or aqueous media are important for organic synthesis, realizing high-yielding processes under non-toxic and environmentally friendly conditions. This overview includes (i) a general introduction to organic chemistry in water and aqueous media, (ii) synthetic approaches in, on, and with water as well as in heterogeneous phases, (iii) reactions of carbon-centered radicals with water (or deuterium oxide) activated through coordination with various Lewis acids, (iv) photocatalysis in water and aqueous media, and (v) synthetic applications bioinspired by naturally occurring processes. A wide range of chemical processes and synthetic strategies under different experimental conditions have been reviewed that lead to important functional group translocation and transformation reactions, leading to the preparation of complex molecules. These results reveal how water as a solvent/medium/reagent in radical chemistry has matured over the last two decades, with further discoveries anticipated in the near future.
Fil: Chatgiglialoglu, Chryssostomos. Consiglio Nazionale delle Ricerche; Italia
Fil: Barata Vallejo, Sebastian. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica. Cátedra de Química Orgánica I; Argentina. Consiglio Nazionale delle Ricerche; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Giminis, Thanasis. Universidad Nacional y Kapodistriaca de Atenas; Grecia
description Radical reactions in water or aqueous media are important for organic synthesis, realizing high-yielding processes under non-toxic and environmentally friendly conditions. This overview includes (i) a general introduction to organic chemistry in water and aqueous media, (ii) synthetic approaches in, on, and with water as well as in heterogeneous phases, (iii) reactions of carbon-centered radicals with water (or deuterium oxide) activated through coordination with various Lewis acids, (iv) photocatalysis in water and aqueous media, and (v) synthetic applications bioinspired by naturally occurring processes. A wide range of chemical processes and synthetic strategies under different experimental conditions have been reviewed that lead to important functional group translocation and transformation reactions, leading to the preparation of complex molecules. These results reveal how water as a solvent/medium/reagent in radical chemistry has matured over the last two decades, with further discoveries anticipated in the near future.
publishDate 2024
dc.date.none.fl_str_mv 2024-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/235436
Chatgiglialoglu, Chryssostomos; Barata Vallejo, Sebastian; Giminis, Thanasis; Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods; Molecular Diversity Preservation International; Molecules; 29; 3; 1-2024; 1-51
1420-3049
CONICET Digital
CONICET
url http://hdl.handle.net/11336/235436
identifier_str_mv Chatgiglialoglu, Chryssostomos; Barata Vallejo, Sebastian; Giminis, Thanasis; Radical Reactions in Organic Synthesis: Exploring in-, on-, and with-Water Methods; Molecular Diversity Preservation International; Molecules; 29; 3; 1-2024; 1-51
1420-3049
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules29030569
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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