Synthetic organometallic radical chemistry in water

Autores
Postigo, Jose Alberto
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Several organic radical transformations in aqueous media using organometallic chemistry are presented. Group XIV-elements, such as Si and Ge, and Sn-centered radicals make use of novel methodologies in water which employ both hydrophilic and lipophilic substrates without the requirements of surfactants. Different radical initiation techniques that account for effective initiation of the radical chain reactions in aqueous media are also described, such as the thermal decomposition of azo compounds, the direct photolysis (in the absence of an organic peroxide or other photolytic radical promoter) of silanes, dioxygen initiation techniques, and radical initiation in the absence of solvent, and in the presence of adventitious oxygen. Hydrometallation of multiple bonds with (Me3Si)3SiH and germane analogs in water are also described with the above mentioned initiating techniques, under solvent-free conditions, and performed in continuous flow microreactors. The use of other metal-centered radicals that promote synthetically useful organic transformations in water, such as Mg, Mn, and Zn, is presented. These transformations encompass simple organohalide reductions, and several types of carbon-carbon bond forming reactions, demonstrating the wide scope of organometallic radical chemistry in water for accomplishing organic transformations. Group XIII- centered radicals are also shown to be excellent mediators for organic radical reactions in water, such as Barbier-type alkylations and allylations of carbonyl compounds.
Fil: Postigo, Jose Alberto. Universidad de Belgrano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Materia
Radical reactions
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/115005

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spelling Synthetic organometallic radical chemistry in waterPostigo, Jose AlbertoRadical reactionshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Several organic radical transformations in aqueous media using organometallic chemistry are presented. Group XIV-elements, such as Si and Ge, and Sn-centered radicals make use of novel methodologies in water which employ both hydrophilic and lipophilic substrates without the requirements of surfactants. Different radical initiation techniques that account for effective initiation of the radical chain reactions in aqueous media are also described, such as the thermal decomposition of azo compounds, the direct photolysis (in the absence of an organic peroxide or other photolytic radical promoter) of silanes, dioxygen initiation techniques, and radical initiation in the absence of solvent, and in the presence of adventitious oxygen. Hydrometallation of multiple bonds with (Me3Si)3SiH and germane analogs in water are also described with the above mentioned initiating techniques, under solvent-free conditions, and performed in continuous flow microreactors. The use of other metal-centered radicals that promote synthetically useful organic transformations in water, such as Mg, Mn, and Zn, is presented. These transformations encompass simple organohalide reductions, and several types of carbon-carbon bond forming reactions, demonstrating the wide scope of organometallic radical chemistry in water for accomplishing organic transformations. Group XIII- centered radicals are also shown to be excellent mediators for organic radical reactions in water, such as Barbier-type alkylations and allylations of carbonyl compounds.Fil: Postigo, Jose Alberto. Universidad de Belgrano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaBentham Science Publishers2009-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/115005Postigo, Jose Alberto; Synthetic organometallic radical chemistry in water; Bentham Science Publishers; Current Organic Chemistry; 13; 17; 4-2009; 1683-17041385-2728CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.bentham.org/coc/contabs/coc13-17.htmlinfo:eu-repo/semantics/altIdentifier/doi/10.2174/138527209789578045info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:39:36Zoai:ri.conicet.gov.ar:11336/115005instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:39:36.889CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Synthetic organometallic radical chemistry in water
title Synthetic organometallic radical chemistry in water
spellingShingle Synthetic organometallic radical chemistry in water
Postigo, Jose Alberto
Radical reactions
title_short Synthetic organometallic radical chemistry in water
title_full Synthetic organometallic radical chemistry in water
title_fullStr Synthetic organometallic radical chemistry in water
title_full_unstemmed Synthetic organometallic radical chemistry in water
title_sort Synthetic organometallic radical chemistry in water
dc.creator.none.fl_str_mv Postigo, Jose Alberto
author Postigo, Jose Alberto
author_facet Postigo, Jose Alberto
author_role author
dc.subject.none.fl_str_mv Radical reactions
topic Radical reactions
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Several organic radical transformations in aqueous media using organometallic chemistry are presented. Group XIV-elements, such as Si and Ge, and Sn-centered radicals make use of novel methodologies in water which employ both hydrophilic and lipophilic substrates without the requirements of surfactants. Different radical initiation techniques that account for effective initiation of the radical chain reactions in aqueous media are also described, such as the thermal decomposition of azo compounds, the direct photolysis (in the absence of an organic peroxide or other photolytic radical promoter) of silanes, dioxygen initiation techniques, and radical initiation in the absence of solvent, and in the presence of adventitious oxygen. Hydrometallation of multiple bonds with (Me3Si)3SiH and germane analogs in water are also described with the above mentioned initiating techniques, under solvent-free conditions, and performed in continuous flow microreactors. The use of other metal-centered radicals that promote synthetically useful organic transformations in water, such as Mg, Mn, and Zn, is presented. These transformations encompass simple organohalide reductions, and several types of carbon-carbon bond forming reactions, demonstrating the wide scope of organometallic radical chemistry in water for accomplishing organic transformations. Group XIII- centered radicals are also shown to be excellent mediators for organic radical reactions in water, such as Barbier-type alkylations and allylations of carbonyl compounds.
Fil: Postigo, Jose Alberto. Universidad de Belgrano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
description Several organic radical transformations in aqueous media using organometallic chemistry are presented. Group XIV-elements, such as Si and Ge, and Sn-centered radicals make use of novel methodologies in water which employ both hydrophilic and lipophilic substrates without the requirements of surfactants. Different radical initiation techniques that account for effective initiation of the radical chain reactions in aqueous media are also described, such as the thermal decomposition of azo compounds, the direct photolysis (in the absence of an organic peroxide or other photolytic radical promoter) of silanes, dioxygen initiation techniques, and radical initiation in the absence of solvent, and in the presence of adventitious oxygen. Hydrometallation of multiple bonds with (Me3Si)3SiH and germane analogs in water are also described with the above mentioned initiating techniques, under solvent-free conditions, and performed in continuous flow microreactors. The use of other metal-centered radicals that promote synthetically useful organic transformations in water, such as Mg, Mn, and Zn, is presented. These transformations encompass simple organohalide reductions, and several types of carbon-carbon bond forming reactions, demonstrating the wide scope of organometallic radical chemistry in water for accomplishing organic transformations. Group XIII- centered radicals are also shown to be excellent mediators for organic radical reactions in water, such as Barbier-type alkylations and allylations of carbonyl compounds.
publishDate 2009
dc.date.none.fl_str_mv 2009-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/115005
Postigo, Jose Alberto; Synthetic organometallic radical chemistry in water; Bentham Science Publishers; Current Organic Chemistry; 13; 17; 4-2009; 1683-1704
1385-2728
CONICET Digital
CONICET
url http://hdl.handle.net/11336/115005
identifier_str_mv Postigo, Jose Alberto; Synthetic organometallic radical chemistry in water; Bentham Science Publishers; Current Organic Chemistry; 13; 17; 4-2009; 1683-1704
1385-2728
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.bentham.org/coc/contabs/coc13-17.html
info:eu-repo/semantics/altIdentifier/doi/10.2174/138527209789578045
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432