Circadian dysregulation in Parkinson's disease

Autores
Videnovic, Aleksandar; Golombek, Diego Andrés
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects over one million individuals in the US alone. PD is characterized by a plethora of motor and non-motor manifestations, resulting from a progressive degeneration of dopaminergic neurons and disbalance of several other neurotransmitters. A growing body of evidence points to significant alterations of the circadian system in PD. This is not surprising given the pivotal role that dopamine plays in circadian regulation as well as the role of circadian influences in dopamine metabolism. In this review we present basic and clinical investigations that examined the function of the circadian system in PD.
Fil: Videnovic, Aleksandar. Massachusetts General Hospital ; Department Of Medicine ; Harvard Medical School;
Fil: Golombek, Diego Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Materia
CIRCADIAN
CLOCK GENES
DOPAMINE
PARKINSON'S
SLEEP
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/77412
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/77412
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Circadian dysregulation in Parkinson's diseaseVidenovic, AleksandarGolombek, Diego AndrésCIRCADIANCLOCK GENESDOPAMINEPARKINSON'SSLEEPhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects over one million individuals in the US alone. PD is characterized by a plethora of motor and non-motor manifestations, resulting from a progressive degeneration of dopaminergic neurons and disbalance of several other neurotransmitters. A growing body of evidence points to significant alterations of the circadian system in PD. This is not surprising given the pivotal role that dopamine plays in circadian regulation as well as the role of circadian influences in dopamine metabolism. In this review we present basic and clinical investigations that examined the function of the circadian system in PD.Fil: Videnovic, Aleksandar. Massachusetts General Hospital ; Department Of Medicine ; Harvard Medical School;Fil: Golombek, Diego Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; ArgentinaElsevier Inc2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/77412Videnovic, Aleksandar; Golombek, Diego Andrés; Circadian dysregulation in Parkinson's disease; Elsevier Inc; Neurobiology of Sleep and Circadian Rhythms; 2; 3-2017; 53-582451-9944CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.nbscr.2016.11.001info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2451994416300177info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:34:18Zoai:ri.conicet.gov.ar:11336/77412instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:34:18.992CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Circadian dysregulation in Parkinson's disease
title Circadian dysregulation in Parkinson's disease
spellingShingle Circadian dysregulation in Parkinson's disease
Videnovic, Aleksandar
CIRCADIAN
CLOCK GENES
DOPAMINE
PARKINSON'S
SLEEP
title_short Circadian dysregulation in Parkinson's disease
title_full Circadian dysregulation in Parkinson's disease
title_fullStr Circadian dysregulation in Parkinson's disease
title_full_unstemmed Circadian dysregulation in Parkinson's disease
title_sort Circadian dysregulation in Parkinson's disease
dc.creator.none.fl_str_mv Videnovic, Aleksandar
Golombek, Diego Andrés
author Videnovic, Aleksandar
author_facet Videnovic, Aleksandar
Golombek, Diego Andrés
author_role author
author2 Golombek, Diego Andrés
author2_role author
dc.subject.none.fl_str_mv CIRCADIAN
CLOCK GENES
DOPAMINE
PARKINSON'S
SLEEP
topic CIRCADIAN
CLOCK GENES
DOPAMINE
PARKINSON'S
SLEEP
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects over one million individuals in the US alone. PD is characterized by a plethora of motor and non-motor manifestations, resulting from a progressive degeneration of dopaminergic neurons and disbalance of several other neurotransmitters. A growing body of evidence points to significant alterations of the circadian system in PD. This is not surprising given the pivotal role that dopamine plays in circadian regulation as well as the role of circadian influences in dopamine metabolism. In this review we present basic and clinical investigations that examined the function of the circadian system in PD.
Fil: Videnovic, Aleksandar. Massachusetts General Hospital ; Department Of Medicine ; Harvard Medical School;
Fil: Golombek, Diego Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
description Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects over one million individuals in the US alone. PD is characterized by a plethora of motor and non-motor manifestations, resulting from a progressive degeneration of dopaminergic neurons and disbalance of several other neurotransmitters. A growing body of evidence points to significant alterations of the circadian system in PD. This is not surprising given the pivotal role that dopamine plays in circadian regulation as well as the role of circadian influences in dopamine metabolism. In this review we present basic and clinical investigations that examined the function of the circadian system in PD.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/77412
Videnovic, Aleksandar; Golombek, Diego Andrés; Circadian dysregulation in Parkinson's disease; Elsevier Inc; Neurobiology of Sleep and Circadian Rhythms; 2; 3-2017; 53-58
2451-9944
CONICET Digital
CONICET
url http://hdl.handle.net/11336/77412
identifier_str_mv Videnovic, Aleksandar; Golombek, Diego Andrés; Circadian dysregulation in Parkinson's disease; Elsevier Inc; Neurobiology of Sleep and Circadian Rhythms; 2; 3-2017; 53-58
2451-9944
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.nbscr.2016.11.001
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2451994416300177
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Inc
publisher.none.fl_str_mv Elsevier Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613061281841152
score 13.069144

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