Bio-inspired silica–collagen materials: applications and perspectives in the medical field

Autores
Heinemann, Sascha; Coradin, Thibaud; Desimone, Martín Federico
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Silica and collagen are two of the most abundant substances in the Earth's geosphere and biosphere, respectively. Yet, their close association in nature has never been clearly demonstrated despite increasing evidence for the key role of silicon in mammalians. Foreseeing the therapeutic benefits of their association within composites or hybrids, a wide diversity of bio-inspired silica–collagen materials have been prepared over nearly 15 years. These works not only generated materials with a large range of structures and properties, from soft mineralized hydrogels to hard compact xerogels, but also provided more fundamental information about the interplay between polymer self-assembly processes and inorganic condensation mechanisms. Biological in vitro and in vivo evaluations suggest their bioactivity, cyto- and biocompatibility as well as controlled drug delivery properties. Hence they can now fully integrate the family of materials with high potential for the development of innovative biomedical devices.
Fil: Heinemann, Sascha. Technische Universität Dresden; Alemania
Fil: Coradin, Thibaud. Centre National de la Recherche Scientifique; Francia. Universite de Paris Vi; Francia
Fil: Desimone, Martín Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Materia
Silica
Collagen
Biomaterials
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/18473
Acceder
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spelling Bio-inspired silica–collagen materials: applications and perspectives in the medical fieldHeinemann, SaschaCoradin, ThibaudDesimone, Martín FedericoSilicaCollagenBiomaterialshttps://purl.org/becyt/ford/3.4https://purl.org/becyt/ford/3Silica and collagen are two of the most abundant substances in the Earth's geosphere and biosphere, respectively. Yet, their close association in nature has never been clearly demonstrated despite increasing evidence for the key role of silicon in mammalians. Foreseeing the therapeutic benefits of their association within composites or hybrids, a wide diversity of bio-inspired silica–collagen materials have been prepared over nearly 15 years. These works not only generated materials with a large range of structures and properties, from soft mineralized hydrogels to hard compact xerogels, but also provided more fundamental information about the interplay between polymer self-assembly processes and inorganic condensation mechanisms. Biological in vitro and in vivo evaluations suggest their bioactivity, cyto- and biocompatibility as well as controlled drug delivery properties. Hence they can now fully integrate the family of materials with high potential for the development of innovative biomedical devices.Fil: Heinemann, Sascha. Technische Universität Dresden; AlemaniaFil: Coradin, Thibaud. Centre National de la Recherche Scientifique; Francia. Universite de Paris Vi; FranciaFil: Desimone, Martín Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaRoyal Society of Chemistry2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/18473Heinemann, Sascha; Coradin, Thibaud; Desimone, Martín Federico; Bio-inspired silica–collagen materials: applications and perspectives in the medical field; Royal Society of Chemistry; Biomaterials Science; 1; 7; 6-2013; 688-7022047-4830CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/content/articlelanding/2013/bm/c3bm00014a#!divAbstractinfo:eu-repo/semantics/altIdentifier/doi/10.1039/C3BM00014Ainfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T11:27:45Zoai:ri.conicet.gov.ar:11336/18473instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 11:27:45.599CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Bio-inspired silica–collagen materials: applications and perspectives in the medical field
title Bio-inspired silica–collagen materials: applications and perspectives in the medical field
spellingShingle Bio-inspired silica–collagen materials: applications and perspectives in the medical field
Heinemann, Sascha
Silica
Collagen
Biomaterials
title_short Bio-inspired silica–collagen materials: applications and perspectives in the medical field
title_full Bio-inspired silica–collagen materials: applications and perspectives in the medical field
title_fullStr Bio-inspired silica–collagen materials: applications and perspectives in the medical field
title_full_unstemmed Bio-inspired silica–collagen materials: applications and perspectives in the medical field
title_sort Bio-inspired silica–collagen materials: applications and perspectives in the medical field
dc.creator.none.fl_str_mv Heinemann, Sascha
Coradin, Thibaud
Desimone, Martín Federico
author Heinemann, Sascha
author_facet Heinemann, Sascha
Coradin, Thibaud
Desimone, Martín Federico
author_role author
author2 Coradin, Thibaud
Desimone, Martín Federico
author2_role author
author
dc.subject.none.fl_str_mv Silica
Collagen
Biomaterials
topic Silica
Collagen
Biomaterials
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Silica and collagen are two of the most abundant substances in the Earth's geosphere and biosphere, respectively. Yet, their close association in nature has never been clearly demonstrated despite increasing evidence for the key role of silicon in mammalians. Foreseeing the therapeutic benefits of their association within composites or hybrids, a wide diversity of bio-inspired silica–collagen materials have been prepared over nearly 15 years. These works not only generated materials with a large range of structures and properties, from soft mineralized hydrogels to hard compact xerogels, but also provided more fundamental information about the interplay between polymer self-assembly processes and inorganic condensation mechanisms. Biological in vitro and in vivo evaluations suggest their bioactivity, cyto- and biocompatibility as well as controlled drug delivery properties. Hence they can now fully integrate the family of materials with high potential for the development of innovative biomedical devices.
Fil: Heinemann, Sascha. Technische Universität Dresden; Alemania
Fil: Coradin, Thibaud. Centre National de la Recherche Scientifique; Francia. Universite de Paris Vi; Francia
Fil: Desimone, Martín Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
description Silica and collagen are two of the most abundant substances in the Earth's geosphere and biosphere, respectively. Yet, their close association in nature has never been clearly demonstrated despite increasing evidence for the key role of silicon in mammalians. Foreseeing the therapeutic benefits of their association within composites or hybrids, a wide diversity of bio-inspired silica–collagen materials have been prepared over nearly 15 years. These works not only generated materials with a large range of structures and properties, from soft mineralized hydrogels to hard compact xerogels, but also provided more fundamental information about the interplay between polymer self-assembly processes and inorganic condensation mechanisms. Biological in vitro and in vivo evaluations suggest their bioactivity, cyto- and biocompatibility as well as controlled drug delivery properties. Hence they can now fully integrate the family of materials with high potential for the development of innovative biomedical devices.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/18473
Heinemann, Sascha; Coradin, Thibaud; Desimone, Martín Federico; Bio-inspired silica–collagen materials: applications and perspectives in the medical field; Royal Society of Chemistry; Biomaterials Science; 1; 7; 6-2013; 688-702
2047-4830
CONICET Digital
CONICET
url http://hdl.handle.net/11336/18473
identifier_str_mv Heinemann, Sascha; Coradin, Thibaud; Desimone, Martín Federico; Bio-inspired silica–collagen materials: applications and perspectives in the medical field; Royal Society of Chemistry; Biomaterials Science; 1; 7; 6-2013; 688-702
2047-4830
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/content/articlelanding/2013/bm/c3bm00014a#!divAbstract
info:eu-repo/semantics/altIdentifier/doi/10.1039/C3BM00014A
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.000565

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