Fertility Issues in Disorders of Sex Development

Autores
Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology. In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation. In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood. In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.
Fil: Guercio, Gabriela Viviana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Constanzo, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Grinspon, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Materia
Genitales Ambiguos
Desorden de La Diferenciación Sexual
Fertilidad
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8180
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Fertility Issues in Disorders of Sex DevelopmentGuercio, Gabriela VivianaConstanzo, MarianaGrinspon, RominaRey, Rodolfo AlbertoGenitales AmbiguosDesorden de La Diferenciación SexualFertilidadhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology. In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation. In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood. In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.Fil: Guercio, Gabriela Viviana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Constanzo, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Grinspon, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; ArgentinaFil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaElsevier2015-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8180Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto; Fertility Issues in Disorders of Sex Development; Elsevier; Endocrinology And Metabolism Clinics Of North America; 44; 4; 9-2015; 867-8810889-8529enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0889852915000882info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ecl.2015.07.012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T10:48:41Zoai:ri.conicet.gov.ar:11336/8180instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 10:48:42.116CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Fertility Issues in Disorders of Sex Development
title Fertility Issues in Disorders of Sex Development
spellingShingle Fertility Issues in Disorders of Sex Development
Guercio, Gabriela Viviana
Genitales Ambiguos
Desorden de La Diferenciación Sexual
Fertilidad
title_short Fertility Issues in Disorders of Sex Development
title_full Fertility Issues in Disorders of Sex Development
title_fullStr Fertility Issues in Disorders of Sex Development
title_full_unstemmed Fertility Issues in Disorders of Sex Development
title_sort Fertility Issues in Disorders of Sex Development
dc.creator.none.fl_str_mv Guercio, Gabriela Viviana
Constanzo, Mariana
Grinspon, Romina
Rey, Rodolfo Alberto
author Guercio, Gabriela Viviana
author_facet Guercio, Gabriela Viviana
Constanzo, Mariana
Grinspon, Romina
Rey, Rodolfo Alberto
author_role author
author2 Constanzo, Mariana
Grinspon, Romina
Rey, Rodolfo Alberto
author2_role author
author
author
dc.subject.none.fl_str_mv Genitales Ambiguos
Desorden de La Diferenciación Sexual
Fertilidad
topic Genitales Ambiguos
Desorden de La Diferenciación Sexual
Fertilidad
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology. In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation. In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood. In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.
Fil: Guercio, Gabriela Viviana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Constanzo, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
Fil: Grinspon, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina
Fil: Rey, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
description Fertility potential in patients with disorders of sex development is influenced by specific factors related to the causal disorder, and general functional and anatomic features, irrespective of the etiology. In patients with testicular dysgenesis, severe forms are raised as females, and motherhood might be possible with hormone replacement and oocyte donation. In patients with specific defects of androgen synthesis or action, the absence of uterus and Fallopian tubes hampers motherhood. In some virilized 46,XX patients raised as females, fertility is possible after adequate hormonal and surgical treatments. Patients raised as males are most frequently oligospermic or azoospermic, with the exception for milder forms, where full spermatogenesis can be achieved spontaneously or after hormonal treatment.
publishDate 2015
dc.date.none.fl_str_mv 2015-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8180
Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto; Fertility Issues in Disorders of Sex Development; Elsevier; Endocrinology And Metabolism Clinics Of North America; 44; 4; 9-2015; 867-881
0889-8529
url http://hdl.handle.net/11336/8180
identifier_str_mv Guercio, Gabriela Viviana; Constanzo, Mariana; Grinspon, Romina; Rey, Rodolfo Alberto; Fertility Issues in Disorders of Sex Development; Elsevier; Endocrinology And Metabolism Clinics Of North America; 44; 4; 9-2015; 867-881
0889-8529
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0889852915000882
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ecl.2015.07.012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.087074

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