Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields

Autores
Franzoni, Maria Belen; Buljubasich Gentiletti, Lisandro; Spiess, Hans W.; Münnemann, Kerstin
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nuclear magnetic resonance (NMR) is a very powerful tool in physics, chemistry, and life sciences, although limited by low sensitivity. This problem can be overcome by hyperpolarization techniques dramatically enhancing the NMR signal. However, this approach is restricted to relatively short time scales depending on the nuclear spin-lattice relaxation time T1 in the range of seconds. This makes long-lived singlet states very useful as a way to extend the hyperpolarization lifetimes. Para-hydrogen induced polarization (PHIP) is particularly suitable, because para-H2 possesses singlet symmetry. Most PHIP experiments, however, are performed on asymmetric molecules, and the initial singlet state is directly converted to a NMR observable triplet state decaying with T1, in the order of seconds. We demonstrate that in symmetric molecules, a long-lived singlet state created by PHIP can be stored for several minutes on protons in high magnetic fields. Subsequently, it is converted into observable high nonthermal magnetization by controlled singlet-triplet conversion via level anticrossing.
Fil: Franzoni, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Buljubasich Gentiletti, Lisandro. Max Planck Institute for Polymer Research; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Spiess, Hans W.. Max Planck Institute for Polymer Research; Alemania
Fil: Münnemann, Kerstin. Max Planck Institute for Polymer Research; Alemania
Materia
ParaHydrogen
Hyperpolarization
Nuclear Magnetic Resonance
Long lived states
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/268548
Acceder
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spelling Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic FieldsFranzoni, Maria BelenBuljubasich Gentiletti, LisandroSpiess, Hans W.Münnemann, KerstinParaHydrogenHyperpolarizationNuclear Magnetic ResonanceLong lived stateshttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Nuclear magnetic resonance (NMR) is a very powerful tool in physics, chemistry, and life sciences, although limited by low sensitivity. This problem can be overcome by hyperpolarization techniques dramatically enhancing the NMR signal. However, this approach is restricted to relatively short time scales depending on the nuclear spin-lattice relaxation time T1 in the range of seconds. This makes long-lived singlet states very useful as a way to extend the hyperpolarization lifetimes. Para-hydrogen induced polarization (PHIP) is particularly suitable, because para-H2 possesses singlet symmetry. Most PHIP experiments, however, are performed on asymmetric molecules, and the initial singlet state is directly converted to a NMR observable triplet state decaying with T1, in the order of seconds. We demonstrate that in symmetric molecules, a long-lived singlet state created by PHIP can be stored for several minutes on protons in high magnetic fields. Subsequently, it is converted into observable high nonthermal magnetization by controlled singlet-triplet conversion via level anticrossing.Fil: Franzoni, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Buljubasich Gentiletti, Lisandro. Max Planck Institute for Polymer Research; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Spiess, Hans W.. Max Planck Institute for Polymer Research; AlemaniaFil: Münnemann, Kerstin. Max Planck Institute for Polymer Research; AlemaniaAmerican Chemical Society2012-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/268548Franzoni, Maria Belen; Buljubasich Gentiletti, Lisandro; Spiess, Hans W.; Münnemann, Kerstin; Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields; American Chemical Society; Journal of the American Chemical Society; 134; 25; 6-2012; 10393-103960002-7863CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/ja304285sinfo:eu-repo/semantics/altIdentifier/doi/10.1021/ja304285sinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:52:11Zoai:ri.conicet.gov.ar:11336/268548instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:52:11.458CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
title Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
spellingShingle Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
Franzoni, Maria Belen
ParaHydrogen
Hyperpolarization
Nuclear Magnetic Resonance
Long lived states
title_short Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
title_full Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
title_fullStr Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
title_full_unstemmed Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
title_sort Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields
dc.creator.none.fl_str_mv Franzoni, Maria Belen
Buljubasich Gentiletti, Lisandro
Spiess, Hans W.
Münnemann, Kerstin
author Franzoni, Maria Belen
author_facet Franzoni, Maria Belen
Buljubasich Gentiletti, Lisandro
Spiess, Hans W.
Münnemann, Kerstin
author_role author
author2 Buljubasich Gentiletti, Lisandro
Spiess, Hans W.
Münnemann, Kerstin
author2_role author
author
author
dc.subject.none.fl_str_mv ParaHydrogen
Hyperpolarization
Nuclear Magnetic Resonance
Long lived states
topic ParaHydrogen
Hyperpolarization
Nuclear Magnetic Resonance
Long lived states
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Nuclear magnetic resonance (NMR) is a very powerful tool in physics, chemistry, and life sciences, although limited by low sensitivity. This problem can be overcome by hyperpolarization techniques dramatically enhancing the NMR signal. However, this approach is restricted to relatively short time scales depending on the nuclear spin-lattice relaxation time T1 in the range of seconds. This makes long-lived singlet states very useful as a way to extend the hyperpolarization lifetimes. Para-hydrogen induced polarization (PHIP) is particularly suitable, because para-H2 possesses singlet symmetry. Most PHIP experiments, however, are performed on asymmetric molecules, and the initial singlet state is directly converted to a NMR observable triplet state decaying with T1, in the order of seconds. We demonstrate that in symmetric molecules, a long-lived singlet state created by PHIP can be stored for several minutes on protons in high magnetic fields. Subsequently, it is converted into observable high nonthermal magnetization by controlled singlet-triplet conversion via level anticrossing.
Fil: Franzoni, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Buljubasich Gentiletti, Lisandro. Max Planck Institute for Polymer Research; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Spiess, Hans W.. Max Planck Institute for Polymer Research; Alemania
Fil: Münnemann, Kerstin. Max Planck Institute for Polymer Research; Alemania
description Nuclear magnetic resonance (NMR) is a very powerful tool in physics, chemistry, and life sciences, although limited by low sensitivity. This problem can be overcome by hyperpolarization techniques dramatically enhancing the NMR signal. However, this approach is restricted to relatively short time scales depending on the nuclear spin-lattice relaxation time T1 in the range of seconds. This makes long-lived singlet states very useful as a way to extend the hyperpolarization lifetimes. Para-hydrogen induced polarization (PHIP) is particularly suitable, because para-H2 possesses singlet symmetry. Most PHIP experiments, however, are performed on asymmetric molecules, and the initial singlet state is directly converted to a NMR observable triplet state decaying with T1, in the order of seconds. We demonstrate that in symmetric molecules, a long-lived singlet state created by PHIP can be stored for several minutes on protons in high magnetic fields. Subsequently, it is converted into observable high nonthermal magnetization by controlled singlet-triplet conversion via level anticrossing.
publishDate 2012
dc.date.none.fl_str_mv 2012-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/268548
Franzoni, Maria Belen; Buljubasich Gentiletti, Lisandro; Spiess, Hans W.; Münnemann, Kerstin; Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields; American Chemical Society; Journal of the American Chemical Society; 134; 25; 6-2012; 10393-10396
0002-7863
CONICET Digital
CONICET
url http://hdl.handle.net/11336/268548
identifier_str_mv Franzoni, Maria Belen; Buljubasich Gentiletti, Lisandro; Spiess, Hans W.; Münnemann, Kerstin; Long-Lived 1 H Singlet Spin States Originating from Para-Hydrogen in Cs-Symmetric Molecules Stored for Minutes in High Magnetic Fields; American Chemical Society; Journal of the American Chemical Society; 134; 25; 6-2012; 10393-10396
0002-7863
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/ja304285s
info:eu-repo/semantics/altIdentifier/doi/10.1021/ja304285s
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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