Chitosan films modified selectively on one side with dendritic molecules

Autores
Aldana, Ana Agustina; Toselli, Ricardo Javier; Strumia, Miriam Cristina; Martinelli, Maria Laura
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Novel chitosan films dendronized on one side were prepared by reaction between a cross-linked biopolymer and weisocyanate dendron. According to ATR-FTIR analysis, it can be concluded that the dendronization took place on only one of the faces of the films. The highlight of this work is that the modification grants different hydrophilic and hydrophobic properties on both sides of the system. Interactions between the dendron-polymer network and the hydrophobic characteristics of the dendron modify the physical properties of the films. As the thermal stability of the films increases, the degree of swelling and WVP values decrease, and the elastic modulus increases, turning the network more rigid. The dendronized films were swollen at pH 3.4 and 6.8 which are the pHs of the different wound healing stages. The films remained stable for an extended period. The films obtained can be potentially applied as wound dressings able to maintain a moist environment at the wound interface and act as a barrier to microorganisms, removing excess exudates. The product is made from a readily available biomaterial that requires minimal processing, possesses antimicrobial properties and could promote wound healing.
Fil: Aldana, Ana Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Toselli, Ricardo Javier. Universidad Nacional de Cordoba. Facultad de Cs.quimicas. Centro de Quimica Aplicada; Argentina
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Martinelli, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Materia
Films
Chitosan
Dendron
Wound Dressing
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/18416
Acceder
id CONICETDig_ba2d392ca8576f309e82b04b62a7ba08
oai_identifier_str oai:ri.conicet.gov.ar:11336/18416
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chitosan films modified selectively on one side with dendritic moleculesAldana, Ana AgustinaToselli, Ricardo JavierStrumia, Miriam CristinaMartinelli, Maria LauraFilmsChitosanDendronWound Dressinghttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Novel chitosan films dendronized on one side were prepared by reaction between a cross-linked biopolymer and weisocyanate dendron. According to ATR-FTIR analysis, it can be concluded that the dendronization took place on only one of the faces of the films. The highlight of this work is that the modification grants different hydrophilic and hydrophobic properties on both sides of the system. Interactions between the dendron-polymer network and the hydrophobic characteristics of the dendron modify the physical properties of the films. As the thermal stability of the films increases, the degree of swelling and WVP values decrease, and the elastic modulus increases, turning the network more rigid. The dendronized films were swollen at pH 3.4 and 6.8 which are the pHs of the different wound healing stages. The films remained stable for an extended period. The films obtained can be potentially applied as wound dressings able to maintain a moist environment at the wound interface and act as a barrier to microorganisms, removing excess exudates. The product is made from a readily available biomaterial that requires minimal processing, possesses antimicrobial properties and could promote wound healing.Fil: Aldana, Ana Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Toselli, Ricardo Javier. Universidad Nacional de Cordoba. Facultad de Cs.quimicas. Centro de Quimica Aplicada; ArgentinaFil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Martinelli, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaRoyal Society Of Chemistry2012-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/18416Aldana, Ana Agustina; Toselli, Ricardo Javier; Strumia, Miriam Cristina; Martinelli, Maria Laura; Chitosan films modified selectively on one side with dendritic molecules; Royal Society Of Chemistry; Journal Of Materials Chemistry; 22; 42; 11-2012; 22670-226770959-9428CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/content/articlelanding/2012/jm/c2jm33100dinfo:eu-repo/semantics/altIdentifier/doi/10.1039/C2JM33100Dinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:05:04Zoai:ri.conicet.gov.ar:11336/18416instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:05:04.467CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chitosan films modified selectively on one side with dendritic molecules
title Chitosan films modified selectively on one side with dendritic molecules
spellingShingle Chitosan films modified selectively on one side with dendritic molecules
Aldana, Ana Agustina
Films
Chitosan
Dendron
Wound Dressing
title_short Chitosan films modified selectively on one side with dendritic molecules
title_full Chitosan films modified selectively on one side with dendritic molecules
title_fullStr Chitosan films modified selectively on one side with dendritic molecules
title_full_unstemmed Chitosan films modified selectively on one side with dendritic molecules
title_sort Chitosan films modified selectively on one side with dendritic molecules
dc.creator.none.fl_str_mv Aldana, Ana Agustina
Toselli, Ricardo Javier
Strumia, Miriam Cristina
Martinelli, Maria Laura
author Aldana, Ana Agustina
author_facet Aldana, Ana Agustina
Toselli, Ricardo Javier
Strumia, Miriam Cristina
Martinelli, Maria Laura
author_role author
author2 Toselli, Ricardo Javier
Strumia, Miriam Cristina
Martinelli, Maria Laura
author2_role author
author
author
dc.subject.none.fl_str_mv Films
Chitosan
Dendron
Wound Dressing
topic Films
Chitosan
Dendron
Wound Dressing
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Novel chitosan films dendronized on one side were prepared by reaction between a cross-linked biopolymer and weisocyanate dendron. According to ATR-FTIR analysis, it can be concluded that the dendronization took place on only one of the faces of the films. The highlight of this work is that the modification grants different hydrophilic and hydrophobic properties on both sides of the system. Interactions between the dendron-polymer network and the hydrophobic characteristics of the dendron modify the physical properties of the films. As the thermal stability of the films increases, the degree of swelling and WVP values decrease, and the elastic modulus increases, turning the network more rigid. The dendronized films were swollen at pH 3.4 and 6.8 which are the pHs of the different wound healing stages. The films remained stable for an extended period. The films obtained can be potentially applied as wound dressings able to maintain a moist environment at the wound interface and act as a barrier to microorganisms, removing excess exudates. The product is made from a readily available biomaterial that requires minimal processing, possesses antimicrobial properties and could promote wound healing.
Fil: Aldana, Ana Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Toselli, Ricardo Javier. Universidad Nacional de Cordoba. Facultad de Cs.quimicas. Centro de Quimica Aplicada; Argentina
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Martinelli, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
description Novel chitosan films dendronized on one side were prepared by reaction between a cross-linked biopolymer and weisocyanate dendron. According to ATR-FTIR analysis, it can be concluded that the dendronization took place on only one of the faces of the films. The highlight of this work is that the modification grants different hydrophilic and hydrophobic properties on both sides of the system. Interactions between the dendron-polymer network and the hydrophobic characteristics of the dendron modify the physical properties of the films. As the thermal stability of the films increases, the degree of swelling and WVP values decrease, and the elastic modulus increases, turning the network more rigid. The dendronized films were swollen at pH 3.4 and 6.8 which are the pHs of the different wound healing stages. The films remained stable for an extended period. The films obtained can be potentially applied as wound dressings able to maintain a moist environment at the wound interface and act as a barrier to microorganisms, removing excess exudates. The product is made from a readily available biomaterial that requires minimal processing, possesses antimicrobial properties and could promote wound healing.
publishDate 2012
dc.date.none.fl_str_mv 2012-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/18416
Aldana, Ana Agustina; Toselli, Ricardo Javier; Strumia, Miriam Cristina; Martinelli, Maria Laura; Chitosan films modified selectively on one side with dendritic molecules; Royal Society Of Chemistry; Journal Of Materials Chemistry; 22; 42; 11-2012; 22670-22677
0959-9428
CONICET Digital
CONICET
url http://hdl.handle.net/11336/18416
identifier_str_mv Aldana, Ana Agustina; Toselli, Ricardo Javier; Strumia, Miriam Cristina; Martinelli, Maria Laura; Chitosan films modified selectively on one side with dendritic molecules; Royal Society Of Chemistry; Journal Of Materials Chemistry; 22; 42; 11-2012; 22670-22677
0959-9428
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/content/articlelanding/2012/jm/c2jm33100d
info:eu-repo/semantics/altIdentifier/doi/10.1039/C2JM33100D
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society Of Chemistry
publisher.none.fl_str_mv Royal Society Of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980176302964736
score 12.993085

Publicaciones similares