Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation

Autores
Bongiovanni Abel, Silvestre Manuel; Gallarato, Lucas Antonio; Dardanelli, Marta Susana; Barbero, César Alfredo; Rivarola, Claudia Rosana; Yslas, Edith Inés
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Increases in the prevalence of antibiotic resistant bacteria require new approaches for the treatment of infectious bacterial pathogens. A new therapeutic modality, which is called photothermal therapy (PTT) involves the absorption of Near Infrared Radiation (NIR) light by absorbing species (e.g. polyaniline nanoparticles) and transfer of the absorbed energy into the surrounding environment as heat that could cause pathogen death. Since the pathogen cells, and the surrounding tissue, does not absorb NIR radiation, an agent which strongly absorb the light has to be added. In this work, were performed experiments to determine if polyaniline nanoparticles (PANI-NP) in combination with NIR irradiation could be used to destroy Pseudomonas aeruginosa. Results reveal that this nanomaterial, following NIR exposure could be used for killing bacteria because it was observed a significant decrease in cell viability triggering cell death. In addition, the cell death mechanism was observed by DNA fragmentation.
Fil: Bongiovanni Abel, Silvestre Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Gallarato, Lucas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina
Fil: Dardanelli, Marta Susana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Rivarola, Claudia Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Yslas, Edith Inés. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Materia
BACTERIAL DEATH
NANOMATERIALS
PATHOGENIC BACTERIA
PHOTOTHERMAL THERAPY
POLYANILINE NANOPARTICLES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/93361
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiationBongiovanni Abel, Silvestre ManuelGallarato, Lucas AntonioDardanelli, Marta SusanaBarbero, César AlfredoRivarola, Claudia RosanaYslas, Edith InésBACTERIAL DEATHNANOMATERIALSPATHOGENIC BACTERIAPHOTOTHERMAL THERAPYPOLYANILINE NANOPARTICLEShttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2Increases in the prevalence of antibiotic resistant bacteria require new approaches for the treatment of infectious bacterial pathogens. A new therapeutic modality, which is called photothermal therapy (PTT) involves the absorption of Near Infrared Radiation (NIR) light by absorbing species (e.g. polyaniline nanoparticles) and transfer of the absorbed energy into the surrounding environment as heat that could cause pathogen death. Since the pathogen cells, and the surrounding tissue, does not absorb NIR radiation, an agent which strongly absorb the light has to be added. In this work, were performed experiments to determine if polyaniline nanoparticles (PANI-NP) in combination with NIR irradiation could be used to destroy Pseudomonas aeruginosa. Results reveal that this nanomaterial, following NIR exposure could be used for killing bacteria because it was observed a significant decrease in cell viability triggering cell death. In addition, the cell death mechanism was observed by DNA fragmentation.Fil: Bongiovanni Abel, Silvestre Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Gallarato, Lucas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; ArgentinaFil: Dardanelli, Marta Susana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Barbero, César Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Rivarola, Claudia Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Yslas, Edith Inés. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaInstitute of Physics Publishing2018-07-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/93361Bongiovanni Abel, Silvestre Manuel; Gallarato, Lucas Antonio; Dardanelli, Marta Susana; Barbero, César Alfredo; Rivarola, Claudia Rosana; et al.; Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation; Institute of Physics Publishing; Biomedical Physics and Engineering Express; 4; 4; 10-7-20182057-1976CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://iopscience.iop.org/article/10.1088/2057-1976/aacf33info:eu-repo/semantics/altIdentifier/doi/10.1088/2057-1976/aacf33info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:06:26Zoai:ri.conicet.gov.ar:11336/93361instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:06:27.127CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
title Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
spellingShingle Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
Bongiovanni Abel, Silvestre Manuel
BACTERIAL DEATH
NANOMATERIALS
PATHOGENIC BACTERIA
PHOTOTHERMAL THERAPY
POLYANILINE NANOPARTICLES
title_short Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
title_full Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
title_fullStr Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
title_full_unstemmed Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
title_sort Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation
dc.creator.none.fl_str_mv Bongiovanni Abel, Silvestre Manuel
Gallarato, Lucas Antonio
Dardanelli, Marta Susana
Barbero, César Alfredo
Rivarola, Claudia Rosana
Yslas, Edith Inés
author Bongiovanni Abel, Silvestre Manuel
author_facet Bongiovanni Abel, Silvestre Manuel
Gallarato, Lucas Antonio
Dardanelli, Marta Susana
Barbero, César Alfredo
Rivarola, Claudia Rosana
Yslas, Edith Inés
author_role author
author2 Gallarato, Lucas Antonio
Dardanelli, Marta Susana
Barbero, César Alfredo
Rivarola, Claudia Rosana
Yslas, Edith Inés
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv BACTERIAL DEATH
NANOMATERIALS
PATHOGENIC BACTERIA
PHOTOTHERMAL THERAPY
POLYANILINE NANOPARTICLES
topic BACTERIAL DEATH
NANOMATERIALS
PATHOGENIC BACTERIA
PHOTOTHERMAL THERAPY
POLYANILINE NANOPARTICLES
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Increases in the prevalence of antibiotic resistant bacteria require new approaches for the treatment of infectious bacterial pathogens. A new therapeutic modality, which is called photothermal therapy (PTT) involves the absorption of Near Infrared Radiation (NIR) light by absorbing species (e.g. polyaniline nanoparticles) and transfer of the absorbed energy into the surrounding environment as heat that could cause pathogen death. Since the pathogen cells, and the surrounding tissue, does not absorb NIR radiation, an agent which strongly absorb the light has to be added. In this work, were performed experiments to determine if polyaniline nanoparticles (PANI-NP) in combination with NIR irradiation could be used to destroy Pseudomonas aeruginosa. Results reveal that this nanomaterial, following NIR exposure could be used for killing bacteria because it was observed a significant decrease in cell viability triggering cell death. In addition, the cell death mechanism was observed by DNA fragmentation.
Fil: Bongiovanni Abel, Silvestre Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Gallarato, Lucas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina
Fil: Dardanelli, Marta Susana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Rivarola, Claudia Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Yslas, Edith Inés. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
description Increases in the prevalence of antibiotic resistant bacteria require new approaches for the treatment of infectious bacterial pathogens. A new therapeutic modality, which is called photothermal therapy (PTT) involves the absorption of Near Infrared Radiation (NIR) light by absorbing species (e.g. polyaniline nanoparticles) and transfer of the absorbed energy into the surrounding environment as heat that could cause pathogen death. Since the pathogen cells, and the surrounding tissue, does not absorb NIR radiation, an agent which strongly absorb the light has to be added. In this work, were performed experiments to determine if polyaniline nanoparticles (PANI-NP) in combination with NIR irradiation could be used to destroy Pseudomonas aeruginosa. Results reveal that this nanomaterial, following NIR exposure could be used for killing bacteria because it was observed a significant decrease in cell viability triggering cell death. In addition, the cell death mechanism was observed by DNA fragmentation.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/93361
Bongiovanni Abel, Silvestre Manuel; Gallarato, Lucas Antonio; Dardanelli, Marta Susana; Barbero, César Alfredo; Rivarola, Claudia Rosana; et al.; Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation; Institute of Physics Publishing; Biomedical Physics and Engineering Express; 4; 4; 10-7-2018
2057-1976
CONICET Digital
CONICET
url http://hdl.handle.net/11336/93361
identifier_str_mv Bongiovanni Abel, Silvestre Manuel; Gallarato, Lucas Antonio; Dardanelli, Marta Susana; Barbero, César Alfredo; Rivarola, Claudia Rosana; et al.; Photothermal lysis of Pseudomonas aeruginosa by polyaniline nanoparticles under near infrared irradiation; Institute of Physics Publishing; Biomedical Physics and Engineering Express; 4; 4; 10-7-2018
2057-1976
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://iopscience.iop.org/article/10.1088/2057-1976/aacf33
info:eu-repo/semantics/altIdentifier/doi/10.1088/2057-1976/aacf33
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Institute of Physics Publishing
publisher.none.fl_str_mv Institute of Physics Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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