Editorial: Modulating glial cells phenotype. New findings and therapies

Autores
Bellini, Maria Jose; Diz Chaves, Yolanda; Ramos, Alberto Javier
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Aging and neurodegenerative diseases are closely related, and the common point between both scenarios is neuroinflammation. Neuroinflammation is mainly mediated by glial cells, astrocytes, and microglia; while endothelial cells transfer the pro-inflammatory signals from periphery. The mechanism that underlies glial cells activation and neuroinflammation-related damage is not fully understood, being the study of glial cells during aging as well as neurodegenerative diseases, a key point to identify targets and to develop therapies that modulate adverse outcomes and mitigate neurodegeneration. This Research Topic has produced a highly informative collection of original research and reviews, that cover multiple aspects for delving neuroinflammation and glial phenotypic changes in neurological diseases and aging. Researchers have presented their work and views to explain cellular and molecular mechanisms acquired by glial cells as well as possible interventions that can modify their functions and phenotypes associated with a broad spectrum of neurological diseases.
Fil: Bellini, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner". Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner"; Argentina
Fil: Diz Chaves, Yolanda. Universidad de Vigo; España
Fil: Ramos, Alberto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
AGING
ASTROGLIA
INFLAMMATION
MICROGLIA
THERAPIES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/143583
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Editorial: Modulating glial cells phenotype. New findings and therapiesBellini, Maria JoseDiz Chaves, YolandaRamos, Alberto JavierAGINGASTROGLIAINFLAMMATIONMICROGLIATHERAPIEShttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Aging and neurodegenerative diseases are closely related, and the common point between both scenarios is neuroinflammation. Neuroinflammation is mainly mediated by glial cells, astrocytes, and microglia; while endothelial cells transfer the pro-inflammatory signals from periphery. The mechanism that underlies glial cells activation and neuroinflammation-related damage is not fully understood, being the study of glial cells during aging as well as neurodegenerative diseases, a key point to identify targets and to develop therapies that modulate adverse outcomes and mitigate neurodegeneration. This Research Topic has produced a highly informative collection of original research and reviews, that cover multiple aspects for delving neuroinflammation and glial phenotypic changes in neurological diseases and aging. Researchers have presented their work and views to explain cellular and molecular mechanisms acquired by glial cells as well as possible interventions that can modify their functions and phenotypes associated with a broad spectrum of neurological diseases.Fil: Bellini, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner". Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner"; ArgentinaFil: Diz Chaves, Yolanda. Universidad de Vigo; EspañaFil: Ramos, Alberto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFrontiers Media2020-09-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/143583Bellini, Maria Jose; Diz Chaves, Yolanda; Ramos, Alberto Javier; Editorial: Modulating glial cells phenotype. New findings and therapies; Frontiers Media; Frontiers in Aging Neuroscience; 12; 23-9-2020; 1-21663-4365CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2020.594870info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnagi.2020.594870/fullinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:49:29Zoai:ri.conicet.gov.ar:11336/143583instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:49:29.582CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Editorial: Modulating glial cells phenotype. New findings and therapies
title Editorial: Modulating glial cells phenotype. New findings and therapies
spellingShingle Editorial: Modulating glial cells phenotype. New findings and therapies
Bellini, Maria Jose
AGING
ASTROGLIA
INFLAMMATION
MICROGLIA
THERAPIES
title_short Editorial: Modulating glial cells phenotype. New findings and therapies
title_full Editorial: Modulating glial cells phenotype. New findings and therapies
title_fullStr Editorial: Modulating glial cells phenotype. New findings and therapies
title_full_unstemmed Editorial: Modulating glial cells phenotype. New findings and therapies
title_sort Editorial: Modulating glial cells phenotype. New findings and therapies
dc.creator.none.fl_str_mv Bellini, Maria Jose
Diz Chaves, Yolanda
Ramos, Alberto Javier
author Bellini, Maria Jose
author_facet Bellini, Maria Jose
Diz Chaves, Yolanda
Ramos, Alberto Javier
author_role author
author2 Diz Chaves, Yolanda
Ramos, Alberto Javier
author2_role author
author
dc.subject.none.fl_str_mv AGING
ASTROGLIA
INFLAMMATION
MICROGLIA
THERAPIES
topic AGING
ASTROGLIA
INFLAMMATION
MICROGLIA
THERAPIES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Aging and neurodegenerative diseases are closely related, and the common point between both scenarios is neuroinflammation. Neuroinflammation is mainly mediated by glial cells, astrocytes, and microglia; while endothelial cells transfer the pro-inflammatory signals from periphery. The mechanism that underlies glial cells activation and neuroinflammation-related damage is not fully understood, being the study of glial cells during aging as well as neurodegenerative diseases, a key point to identify targets and to develop therapies that modulate adverse outcomes and mitigate neurodegeneration. This Research Topic has produced a highly informative collection of original research and reviews, that cover multiple aspects for delving neuroinflammation and glial phenotypic changes in neurological diseases and aging. Researchers have presented their work and views to explain cellular and molecular mechanisms acquired by glial cells as well as possible interventions that can modify their functions and phenotypes associated with a broad spectrum of neurological diseases.
Fil: Bellini, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner". Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner"; Argentina
Fil: Diz Chaves, Yolanda. Universidad de Vigo; España
Fil: Ramos, Alberto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Aging and neurodegenerative diseases are closely related, and the common point between both scenarios is neuroinflammation. Neuroinflammation is mainly mediated by glial cells, astrocytes, and microglia; while endothelial cells transfer the pro-inflammatory signals from periphery. The mechanism that underlies glial cells activation and neuroinflammation-related damage is not fully understood, being the study of glial cells during aging as well as neurodegenerative diseases, a key point to identify targets and to develop therapies that modulate adverse outcomes and mitigate neurodegeneration. This Research Topic has produced a highly informative collection of original research and reviews, that cover multiple aspects for delving neuroinflammation and glial phenotypic changes in neurological diseases and aging. Researchers have presented their work and views to explain cellular and molecular mechanisms acquired by glial cells as well as possible interventions that can modify their functions and phenotypes associated with a broad spectrum of neurological diseases.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-23
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/143583
Bellini, Maria Jose; Diz Chaves, Yolanda; Ramos, Alberto Javier; Editorial: Modulating glial cells phenotype. New findings and therapies; Frontiers Media; Frontiers in Aging Neuroscience; 12; 23-9-2020; 1-2
1663-4365
CONICET Digital
CONICET
url http://hdl.handle.net/11336/143583
identifier_str_mv Bellini, Maria Jose; Diz Chaves, Yolanda; Ramos, Alberto Javier; Editorial: Modulating glial cells phenotype. New findings and therapies; Frontiers Media; Frontiers in Aging Neuroscience; 12; 23-9-2020; 1-2
1663-4365
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2020.594870
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnagi.2020.594870/full
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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