An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells

Autores
Naujok, O.; Francini, Flavio; Jörns, A.; Lenzen, S.
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic stem cells towards insulin producing cells rather than to neuronal cell types, and to combine this with a strategy for their separation from insulin‐negative cells.
Fil: Naujok, O.. Institute of Clinical Biochemistry; Alemania
Fil: Francini, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentina. Institute of Clinical Biochemistry; Alemania
Fil: Jörns, A.. Hannover Medical School; Alemania. Institute of Clinical Biochemistry; Alemania
Fil: Lenzen, S.. Institute of Clinical Biochemistry; Alemania
Materia
DIABETES
TERAPY
CK19
INSULIN
STEM CELL
MOUSE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/106821
Acceder
id CONICETDig_b0db0694307f5b29ebc1dbdf05109a85
oai_identifier_str oai:ri.conicet.gov.ar:11336/106821
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cellsNaujok, O.Francini, FlavioJörns, A.Lenzen, S.DIABETESTERAPYCK19INSULINSTEM CELLMOUSEhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3https://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic stem cells towards insulin producing cells rather than to neuronal cell types, and to combine this with a strategy for their separation from insulin‐negative cells.Fil: Naujok, O.. Institute of Clinical Biochemistry; AlemaniaFil: Francini, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentina. Institute of Clinical Biochemistry; AlemaniaFil: Jörns, A.. Hannover Medical School; Alemania. Institute of Clinical Biochemistry; AlemaniaFil: Lenzen, S.. Institute of Clinical Biochemistry; AlemaniaWiley Blackwell Publishing, Inc2008-07-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/106821Naujok, O.; Francini, Flavio; Jörns, A.; Lenzen, S.; An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells; Wiley Blackwell Publishing, Inc; Cell Proliferation; 41; 4; 8-7-2008; 607-6240960-7722CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2184.2008.00541.x?sid=nlm%3Apubmedinfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2184.2008.00541.xinfo:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/18616698/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:37:30Zoai:ri.conicet.gov.ar:11336/106821instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:37:31.282CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
title An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
spellingShingle An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
Naujok, O.
DIABETES
TERAPY
CK19
INSULIN
STEM CELL
MOUSE
title_short An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
title_full An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
title_fullStr An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
title_full_unstemmed An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
title_sort An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
dc.creator.none.fl_str_mv Naujok, O.
Francini, Flavio
Jörns, A.
Lenzen, S.
author Naujok, O.
author_facet Naujok, O.
Francini, Flavio
Jörns, A.
Lenzen, S.
author_role author
author2 Francini, Flavio
Jörns, A.
Lenzen, S.
author2_role author
author
author
dc.subject.none.fl_str_mv DIABETES
TERAPY
CK19
INSULIN
STEM CELL
MOUSE
topic DIABETES
TERAPY
CK19
INSULIN
STEM CELL
MOUSE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic stem cells towards insulin producing cells rather than to neuronal cell types, and to combine this with a strategy for their separation from insulin‐negative cells.
Fil: Naujok, O.. Institute of Clinical Biochemistry; Alemania
Fil: Francini, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentina. Institute of Clinical Biochemistry; Alemania
Fil: Jörns, A.. Hannover Medical School; Alemania. Institute of Clinical Biochemistry; Alemania
Fil: Lenzen, S.. Institute of Clinical Biochemistry; Alemania
description Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic stem cells towards insulin producing cells rather than to neuronal cell types, and to combine this with a strategy for their separation from insulin‐negative cells.
publishDate 2008
dc.date.none.fl_str_mv 2008-07-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/106821
Naujok, O.; Francini, Flavio; Jörns, A.; Lenzen, S.; An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells; Wiley Blackwell Publishing, Inc; Cell Proliferation; 41; 4; 8-7-2008; 607-624
0960-7722
CONICET Digital
CONICET
url http://hdl.handle.net/11336/106821
identifier_str_mv Naujok, O.; Francini, Flavio; Jörns, A.; Lenzen, S.; An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells; Wiley Blackwell Publishing, Inc; Cell Proliferation; 41; 4; 8-7-2008; 607-624
0960-7722
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2184.2008.00541.x?sid=nlm%3Apubmed
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2184.2008.00541.x
info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/18616698/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083496029716480
score 13.22299

Publicaciones similares