Regional research priorities in brain and nervous system disorders

Autores
Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; Russell, Vivienne Ann; Xin, Yu
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.
Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; India
Fil: Dang, Hoang Minh. Vietnam National University; Vietnam
Fil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; Argentina
Fil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; Egipto
Fil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados Unidos
Fil: Russell, Vivienne Ann. University of Cape Town; Sudáfrica
Fil: Xin, Yu. Peking University; China
Materia
nervous disorders
brain
research priorities
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/48799

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spelling Regional research priorities in brain and nervous system disordersRavindranath, VijayalakshmiDang, Hoang MinhGoya, Rodolfo GustavoMansour, HaderNimgaonkar, Vishwajit L.Russell, Vivienne AnnXin, Yunervous disordersbrainresearch prioritieshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; IndiaFil: Dang, Hoang Minh. Vietnam National University; VietnamFil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; ArgentinaFil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; EgiptoFil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados UnidosFil: Russell, Vivienne Ann. University of Cape Town; SudáfricaFil: Xin, Yu. Peking University; ChinaNature Publishing Group2015-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48799Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E2060028-0836CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1038/nature16036info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature16036info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:15:06Zoai:ri.conicet.gov.ar:11336/48799instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:15:07.209CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Regional research priorities in brain and nervous system disorders
title Regional research priorities in brain and nervous system disorders
spellingShingle Regional research priorities in brain and nervous system disorders
Ravindranath, Vijayalakshmi
nervous disorders
brain
research priorities
title_short Regional research priorities in brain and nervous system disorders
title_full Regional research priorities in brain and nervous system disorders
title_fullStr Regional research priorities in brain and nervous system disorders
title_full_unstemmed Regional research priorities in brain and nervous system disorders
title_sort Regional research priorities in brain and nervous system disorders
dc.creator.none.fl_str_mv Ravindranath, Vijayalakshmi
Dang, Hoang Minh
Goya, Rodolfo Gustavo
Mansour, Hader
Nimgaonkar, Vishwajit L.
Russell, Vivienne Ann
Xin, Yu
author Ravindranath, Vijayalakshmi
author_facet Ravindranath, Vijayalakshmi
Dang, Hoang Minh
Goya, Rodolfo Gustavo
Mansour, Hader
Nimgaonkar, Vishwajit L.
Russell, Vivienne Ann
Xin, Yu
author_role author
author2 Dang, Hoang Minh
Goya, Rodolfo Gustavo
Mansour, Hader
Nimgaonkar, Vishwajit L.
Russell, Vivienne Ann
Xin, Yu
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv nervous disorders
brain
research priorities
topic nervous disorders
brain
research priorities
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.
Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; India
Fil: Dang, Hoang Minh. Vietnam National University; Vietnam
Fil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; Argentina
Fil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; Egipto
Fil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados Unidos
Fil: Russell, Vivienne Ann. University of Cape Town; Sudáfrica
Fil: Xin, Yu. Peking University; China
description The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.
publishDate 2015
dc.date.none.fl_str_mv 2015-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/48799
Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E206
0028-0836
CONICET Digital
CONICET
url http://hdl.handle.net/11336/48799
identifier_str_mv Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E206
0028-0836
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1038/nature16036
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature16036
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
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instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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