Regional research priorities in brain and nervous system disorders
- Autores
- Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; Russell, Vivienne Ann; Xin, Yu
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.
Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; India
Fil: Dang, Hoang Minh. Vietnam National University; Vietnam
Fil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; Argentina
Fil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; Egipto
Fil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados Unidos
Fil: Russell, Vivienne Ann. University of Cape Town; Sudáfrica
Fil: Xin, Yu. Peking University; China - Materia
-
nervous disorders
brain
research priorities - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/48799
Ver los metadatos del registro completo
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Regional research priorities in brain and nervous system disordersRavindranath, VijayalakshmiDang, Hoang MinhGoya, Rodolfo GustavoMansour, HaderNimgaonkar, Vishwajit L.Russell, Vivienne AnnXin, Yunervous disordersbrainresearch prioritieshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; IndiaFil: Dang, Hoang Minh. Vietnam National University; VietnamFil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; ArgentinaFil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; EgiptoFil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados UnidosFil: Russell, Vivienne Ann. University of Cape Town; SudáfricaFil: Xin, Yu. Peking University; ChinaNature Publishing Group2015-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48799Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E2060028-0836CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1038/nature16036info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature16036info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:15:06Zoai:ri.conicet.gov.ar:11336/48799instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:15:07.209CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Regional research priorities in brain and nervous system disorders |
title |
Regional research priorities in brain and nervous system disorders |
spellingShingle |
Regional research priorities in brain and nervous system disorders Ravindranath, Vijayalakshmi nervous disorders brain research priorities |
title_short |
Regional research priorities in brain and nervous system disorders |
title_full |
Regional research priorities in brain and nervous system disorders |
title_fullStr |
Regional research priorities in brain and nervous system disorders |
title_full_unstemmed |
Regional research priorities in brain and nervous system disorders |
title_sort |
Regional research priorities in brain and nervous system disorders |
dc.creator.none.fl_str_mv |
Ravindranath, Vijayalakshmi Dang, Hoang Minh Goya, Rodolfo Gustavo Mansour, Hader Nimgaonkar, Vishwajit L. Russell, Vivienne Ann Xin, Yu |
author |
Ravindranath, Vijayalakshmi |
author_facet |
Ravindranath, Vijayalakshmi Dang, Hoang Minh Goya, Rodolfo Gustavo Mansour, Hader Nimgaonkar, Vishwajit L. Russell, Vivienne Ann Xin, Yu |
author_role |
author |
author2 |
Dang, Hoang Minh Goya, Rodolfo Gustavo Mansour, Hader Nimgaonkar, Vishwajit L. Russell, Vivienne Ann Xin, Yu |
author2_role |
author author author author author author |
dc.subject.none.fl_str_mv |
nervous disorders brain research priorities |
topic |
nervous disorders brain research priorities |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities. Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; India Fil: Dang, Hoang Minh. Vietnam National University; Vietnam Fil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; Argentina Fil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; Egipto Fil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados Unidos Fil: Russell, Vivienne Ann. University of Cape Town; Sudáfrica Fil: Xin, Yu. Peking University; China |
description |
The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/48799 Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E206 0028-0836 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/48799 |
identifier_str_mv |
Ravindranath, Vijayalakshmi; Dang, Hoang Minh; Goya, Rodolfo Gustavo; Mansour, Hader; Nimgaonkar, Vishwajit L.; et al.; Regional research priorities in brain and nervous system disorders; Nature Publishing Group; Nature; 527; 7578; 11-2015; E198-E206 0028-0836 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1038/nature16036 info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature16036 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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