Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents

Autores
López, Romina Vanesa; D'Amato, Roberto; Trabalza Marinucci, Massimo; Regni, Luca; Proietti, Primo; Maratta Martínez, Sergio Ariel; Cerutti, Estela Soledad; Pacheco, Pablo Hugo
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Natural deep eutectic solvents (NADES) were introduced for the extraction of free seleno-amino acids from lyophilized and powdered milk samples. Different NADES were evaluated, and lactic acid:glucose (LGH) showed the highest selenium recoveries. Selenium analysis was performed by inductively coupled plasma mass spectrometry (ICP MS). Se-NADES analysis in ICP MS was optimized according to the radio frequency power and nebulization gas flow rate. Se-NADES extraction was optimized by an experimental design. LGH dilution, LGH volume, sample quantity, and ultrasound time were factors influencing the extraction. Seleno-amino acids were determined by liquid chromatography-ICP MS. After optimization, the limits of detection obtained were 7.37, 8.63, and 9.64 µg kg−1 for selenocysteine, selenomethionine, and seleno-methyl-selenocysteine, respectively. The NADES-extraction is a green procedure with 2 penalty points in the EcoScale. The method was applied to the analysis of powdered milk, lyophilized Se-fortified sheep milk, and ERM-BD151 skimmed milk powder.
Fil: López, Romina Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; Argentina
Fil: D'Amato, Roberto. Università di Perugia; Italia
Fil: Trabalza Marinucci, Massimo. Università di Perugia; Italia
Fil: Regni, Luca. Università di Perugia; Italia
Fil: Proietti, Primo. Università di Perugia; Italia
Fil: Maratta Martínez, Sergio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Investigaciones Mineras; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Pacheco, Pablo Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Materia
ECO-SCALE
FREE SELENO-AMINO ACID
LC-ICP MS
LYOPHILIZED SE-BIOFORTIFIED SHEEP MILK
NADES
POWDER MILK
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/140040
Acceder
id CONICETDig_a91df3a46569950650717459c61733ca
oai_identifier_str oai:ri.conicet.gov.ar:11336/140040
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solventsLópez, Romina VanesaD'Amato, RobertoTrabalza Marinucci, MassimoRegni, LucaProietti, PrimoMaratta Martínez, Sergio ArielCerutti, Estela SoledadPacheco, Pablo HugoECO-SCALEFREE SELENO-AMINO ACIDLC-ICP MSLYOPHILIZED SE-BIOFORTIFIED SHEEP MILKNADESPOWDER MILKhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Natural deep eutectic solvents (NADES) were introduced for the extraction of free seleno-amino acids from lyophilized and powdered milk samples. Different NADES were evaluated, and lactic acid:glucose (LGH) showed the highest selenium recoveries. Selenium analysis was performed by inductively coupled plasma mass spectrometry (ICP MS). Se-NADES analysis in ICP MS was optimized according to the radio frequency power and nebulization gas flow rate. Se-NADES extraction was optimized by an experimental design. LGH dilution, LGH volume, sample quantity, and ultrasound time were factors influencing the extraction. Seleno-amino acids were determined by liquid chromatography-ICP MS. After optimization, the limits of detection obtained were 7.37, 8.63, and 9.64 µg kg−1 for selenocysteine, selenomethionine, and seleno-methyl-selenocysteine, respectively. The NADES-extraction is a green procedure with 2 penalty points in the EcoScale. The method was applied to the analysis of powdered milk, lyophilized Se-fortified sheep milk, and ERM-BD151 skimmed milk powder.Fil: López, Romina Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; ArgentinaFil: D'Amato, Roberto. Università di Perugia; ItaliaFil: Trabalza Marinucci, Massimo. Università di Perugia; ItaliaFil: Regni, Luca. Università di Perugia; ItaliaFil: Proietti, Primo. Università di Perugia; ItaliaFil: Maratta Martínez, Sergio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Investigaciones Mineras; ArgentinaFil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Pacheco, Pablo Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaElsevier2020-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/140040López, Romina Vanesa; D'Amato, Roberto; Trabalza Marinucci, Massimo; Regni, Luca; Proietti, Primo; et al.; Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents; Elsevier; Food Chemistry; 326; 10-2020; 1-330308-8146CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S030881462030827Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodchem.2020.126965info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:39:19Zoai:ri.conicet.gov.ar:11336/140040instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:39:19.847CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
title Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
spellingShingle Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
López, Romina Vanesa
ECO-SCALE
FREE SELENO-AMINO ACID
LC-ICP MS
LYOPHILIZED SE-BIOFORTIFIED SHEEP MILK
NADES
POWDER MILK
title_short Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
title_full Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
title_fullStr Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
title_full_unstemmed Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
title_sort Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents
dc.creator.none.fl_str_mv López, Romina Vanesa
D'Amato, Roberto
Trabalza Marinucci, Massimo
Regni, Luca
Proietti, Primo
Maratta Martínez, Sergio Ariel
Cerutti, Estela Soledad
Pacheco, Pablo Hugo
author López, Romina Vanesa
author_facet López, Romina Vanesa
D'Amato, Roberto
Trabalza Marinucci, Massimo
Regni, Luca
Proietti, Primo
Maratta Martínez, Sergio Ariel
Cerutti, Estela Soledad
Pacheco, Pablo Hugo
author_role author
author2 D'Amato, Roberto
Trabalza Marinucci, Massimo
Regni, Luca
Proietti, Primo
Maratta Martínez, Sergio Ariel
Cerutti, Estela Soledad
Pacheco, Pablo Hugo
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv ECO-SCALE
FREE SELENO-AMINO ACID
LC-ICP MS
LYOPHILIZED SE-BIOFORTIFIED SHEEP MILK
NADES
POWDER MILK
topic ECO-SCALE
FREE SELENO-AMINO ACID
LC-ICP MS
LYOPHILIZED SE-BIOFORTIFIED SHEEP MILK
NADES
POWDER MILK
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Natural deep eutectic solvents (NADES) were introduced for the extraction of free seleno-amino acids from lyophilized and powdered milk samples. Different NADES were evaluated, and lactic acid:glucose (LGH) showed the highest selenium recoveries. Selenium analysis was performed by inductively coupled plasma mass spectrometry (ICP MS). Se-NADES analysis in ICP MS was optimized according to the radio frequency power and nebulization gas flow rate. Se-NADES extraction was optimized by an experimental design. LGH dilution, LGH volume, sample quantity, and ultrasound time were factors influencing the extraction. Seleno-amino acids were determined by liquid chromatography-ICP MS. After optimization, the limits of detection obtained were 7.37, 8.63, and 9.64 µg kg−1 for selenocysteine, selenomethionine, and seleno-methyl-selenocysteine, respectively. The NADES-extraction is a green procedure with 2 penalty points in the EcoScale. The method was applied to the analysis of powdered milk, lyophilized Se-fortified sheep milk, and ERM-BD151 skimmed milk powder.
Fil: López, Romina Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; Argentina
Fil: D'Amato, Roberto. Università di Perugia; Italia
Fil: Trabalza Marinucci, Massimo. Università di Perugia; Italia
Fil: Regni, Luca. Università di Perugia; Italia
Fil: Proietti, Primo. Università di Perugia; Italia
Fil: Maratta Martínez, Sergio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Investigaciones Mineras; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Pacheco, Pablo Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
description Natural deep eutectic solvents (NADES) were introduced for the extraction of free seleno-amino acids from lyophilized and powdered milk samples. Different NADES were evaluated, and lactic acid:glucose (LGH) showed the highest selenium recoveries. Selenium analysis was performed by inductively coupled plasma mass spectrometry (ICP MS). Se-NADES analysis in ICP MS was optimized according to the radio frequency power and nebulization gas flow rate. Se-NADES extraction was optimized by an experimental design. LGH dilution, LGH volume, sample quantity, and ultrasound time were factors influencing the extraction. Seleno-amino acids were determined by liquid chromatography-ICP MS. After optimization, the limits of detection obtained were 7.37, 8.63, and 9.64 µg kg−1 for selenocysteine, selenomethionine, and seleno-methyl-selenocysteine, respectively. The NADES-extraction is a green procedure with 2 penalty points in the EcoScale. The method was applied to the analysis of powdered milk, lyophilized Se-fortified sheep milk, and ERM-BD151 skimmed milk powder.
publishDate 2020
dc.date.none.fl_str_mv 2020-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/140040
López, Romina Vanesa; D'Amato, Roberto; Trabalza Marinucci, Massimo; Regni, Luca; Proietti, Primo; et al.; Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents; Elsevier; Food Chemistry; 326; 10-2020; 1-33
0308-8146
CONICET Digital
CONICET
url http://hdl.handle.net/11336/140040
identifier_str_mv López, Romina Vanesa; D'Amato, Roberto; Trabalza Marinucci, Massimo; Regni, Luca; Proietti, Primo; et al.; Green and simple extraction of free seleno-amino acids from powdered and lyophilized milk samples with natural deep eutectic solvents; Elsevier; Food Chemistry; 326; 10-2020; 1-33
0308-8146
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S030881462030827X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodchem.2020.126965
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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