Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod

Autores
Berón de Astrada, Martín; Bengochea, Mercedes; Sztarker, Julieta; Delorenzi, Alejandro; Tomsic, Daniel
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Due to the complexity and variability of natural environments, the ability to adaptively modify behavior is of fundamental biological importance. Motion vision provides essential cues for guiding critical behaviors such as prey, predator, or mate detection. However, when confronted with the repeated sight of a moving object that turns out to be irrel- evant, most animals will learn to ignore it. The neural mecha- nisms by which moving objects can be ignored are unknown. Although many arthropods exhibit behavioral adaptation to re- petitive moving objects, the underlying neural mechanisms have been difficult to study, due to the difficulty of recording activity from the small columnar neurons in peripheral motion detection circuits. Results: We developed an experimental approach in an arthropod to record the calcium responses of visual neurons in vivo. We show that peripheral columnar neurons that convey visual information into the second optic neuropil persist in responding to the repeated presentation of an innocuous moving object. However, activity in the columnar neurons that convey the visual information from the second to the third optic neuropil is suppressed during high-frequency stimulus repetitions. In accordance with the animal’s behavioral changes, the suppression of neural activity is fast but short lasting and restricted to the retina’s trained area. Conclusions: Columnar neurons from the second optic neuro- pil are likely the main plastic locus responsible for the modifi- cations in animal behavior when confronted with rapidly repeated object motion. Our results demonstrate that visually guided behaviors can be determined by neural plasticity that occurs surprisingly early in the visual pathway.
Fil: Berón de Astrada, Martín. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Bengochea, Mercedes. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Sztarker, Julieta. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Delorenzi, Alejandro. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Tomsic, Daniel. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Materia
Vision
Invertebrate
Neural Circuits
Calcium Imaging
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/785
Acceder
id CONICETDig_a7c8aba3eef078cb25e6adc8c368a950
oai_identifier_str oai:ri.conicet.gov.ar:11336/785
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an ArthropodBerón de Astrada, MartínBengochea, MercedesSztarker, JulietaDelorenzi, AlejandroTomsic, DanielVisionInvertebrateNeural CircuitsCalcium Imaginghttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Background: Due to the complexity and variability of natural environments, the ability to adaptively modify behavior is of fundamental biological importance. Motion vision provides essential cues for guiding critical behaviors such as prey, predator, or mate detection. However, when confronted with the repeated sight of a moving object that turns out to be irrel- evant, most animals will learn to ignore it. The neural mecha- nisms by which moving objects can be ignored are unknown. Although many arthropods exhibit behavioral adaptation to re- petitive moving objects, the underlying neural mechanisms have been difficult to study, due to the difficulty of recording activity from the small columnar neurons in peripheral motion detection circuits. Results: We developed an experimental approach in an arthropod to record the calcium responses of visual neurons in vivo. We show that peripheral columnar neurons that convey visual information into the second optic neuropil persist in responding to the repeated presentation of an innocuous moving object. However, activity in the columnar neurons that convey the visual information from the second to the third optic neuropil is suppressed during high-frequency stimulus repetitions. In accordance with the animal’s behavioral changes, the suppression of neural activity is fast but short lasting and restricted to the retina’s trained area. Conclusions: Columnar neurons from the second optic neuro- pil are likely the main plastic locus responsible for the modifi- cations in animal behavior when confronted with rapidly repeated object motion. Our results demonstrate that visually guided behaviors can be determined by neural plasticity that occurs surprisingly early in the visual pathway.Fil: Berón de Astrada, Martín. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; ArgentinaFil: Bengochea, Mercedes. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; ArgentinaFil: Sztarker, Julieta. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; ArgentinaFil: Delorenzi, Alejandro. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; ArgentinaFil: Tomsic, Daniel. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; ArgentinaCell Press2013-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/785Berón de Astrada, Martín; Bengochea, Mercedes; Sztarker, Julieta; Delorenzi, Alejandro; Tomsic, Daniel; Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod; Cell Press; Current Biology; 23; 8-2013; 8539-85460960-9822enginfo:eu-repo/semantics/altIdentifier/url/http://ac.els-cdn.com/S0960982213007008/1-s2.0-S0960982213007008-main.pdf?_tid=7e843b6c-1469-11e5-810c-00000aab0f27&acdnat=1434488083_500b3e6089bd0cb28198b90f112a7fb8info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cub.2013.05.061info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:48:10Zoai:ri.conicet.gov.ar:11336/785instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:48:10.93CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
title Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
spellingShingle Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
Berón de Astrada, Martín
Vision
Invertebrate
Neural Circuits
Calcium Imaging
title_short Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
title_full Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
title_fullStr Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
title_full_unstemmed Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
title_sort Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod
dc.creator.none.fl_str_mv Berón de Astrada, Martín
Bengochea, Mercedes
Sztarker, Julieta
Delorenzi, Alejandro
Tomsic, Daniel
author Berón de Astrada, Martín
author_facet Berón de Astrada, Martín
Bengochea, Mercedes
Sztarker, Julieta
Delorenzi, Alejandro
Tomsic, Daniel
author_role author
author2 Bengochea, Mercedes
Sztarker, Julieta
Delorenzi, Alejandro
Tomsic, Daniel
author2_role author
author
author
author
dc.subject.none.fl_str_mv Vision
Invertebrate
Neural Circuits
Calcium Imaging
topic Vision
Invertebrate
Neural Circuits
Calcium Imaging
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Background: Due to the complexity and variability of natural environments, the ability to adaptively modify behavior is of fundamental biological importance. Motion vision provides essential cues for guiding critical behaviors such as prey, predator, or mate detection. However, when confronted with the repeated sight of a moving object that turns out to be irrel- evant, most animals will learn to ignore it. The neural mecha- nisms by which moving objects can be ignored are unknown. Although many arthropods exhibit behavioral adaptation to re- petitive moving objects, the underlying neural mechanisms have been difficult to study, due to the difficulty of recording activity from the small columnar neurons in peripheral motion detection circuits. Results: We developed an experimental approach in an arthropod to record the calcium responses of visual neurons in vivo. We show that peripheral columnar neurons that convey visual information into the second optic neuropil persist in responding to the repeated presentation of an innocuous moving object. However, activity in the columnar neurons that convey the visual information from the second to the third optic neuropil is suppressed during high-frequency stimulus repetitions. In accordance with the animal’s behavioral changes, the suppression of neural activity is fast but short lasting and restricted to the retina’s trained area. Conclusions: Columnar neurons from the second optic neuro- pil are likely the main plastic locus responsible for the modifi- cations in animal behavior when confronted with rapidly repeated object motion. Our results demonstrate that visually guided behaviors can be determined by neural plasticity that occurs surprisingly early in the visual pathway.
Fil: Berón de Astrada, Martín. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Bengochea, Mercedes. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Sztarker, Julieta. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Delorenzi, Alejandro. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
Fil: Tomsic, Daniel. Consejo Nacional de Invest.cientif.y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Fisiol., Biol.Molecular y Neurociencias; Argentina
description Background: Due to the complexity and variability of natural environments, the ability to adaptively modify behavior is of fundamental biological importance. Motion vision provides essential cues for guiding critical behaviors such as prey, predator, or mate detection. However, when confronted with the repeated sight of a moving object that turns out to be irrel- evant, most animals will learn to ignore it. The neural mecha- nisms by which moving objects can be ignored are unknown. Although many arthropods exhibit behavioral adaptation to re- petitive moving objects, the underlying neural mechanisms have been difficult to study, due to the difficulty of recording activity from the small columnar neurons in peripheral motion detection circuits. Results: We developed an experimental approach in an arthropod to record the calcium responses of visual neurons in vivo. We show that peripheral columnar neurons that convey visual information into the second optic neuropil persist in responding to the repeated presentation of an innocuous moving object. However, activity in the columnar neurons that convey the visual information from the second to the third optic neuropil is suppressed during high-frequency stimulus repetitions. In accordance with the animal’s behavioral changes, the suppression of neural activity is fast but short lasting and restricted to the retina’s trained area. Conclusions: Columnar neurons from the second optic neuro- pil are likely the main plastic locus responsible for the modifi- cations in animal behavior when confronted with rapidly repeated object motion. Our results demonstrate that visually guided behaviors can be determined by neural plasticity that occurs surprisingly early in the visual pathway.
publishDate 2013
dc.date.none.fl_str_mv 2013-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/785
Berón de Astrada, Martín; Bengochea, Mercedes; Sztarker, Julieta; Delorenzi, Alejandro; Tomsic, Daniel; Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod; Cell Press; Current Biology; 23; 8-2013; 8539-8546
0960-9822
url http://hdl.handle.net/11336/785
identifier_str_mv Berón de Astrada, Martín; Bengochea, Mercedes; Sztarker, Julieta; Delorenzi, Alejandro; Tomsic, Daniel; Identification of Individual Neurons Reflecting Short- and Long-Term Visual Memory in an Arthropod; Cell Press; Current Biology; 23; 8-2013; 8539-8546
0960-9822
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://ac.els-cdn.com/S0960982213007008/1-s2.0-S0960982213007008-main.pdf?_tid=7e843b6c-1469-11e5-810c-00000aab0f27&acdnat=1434488083_500b3e6089bd0cb28198b90f112a7fb8
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cub.2013.05.061
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cell Press
publisher.none.fl_str_mv Cell Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613497883721728
score 13.070432

Publicaciones similares