Oxidative Stress in Muscle Diseases: Current and Future Therapy

Autores
Serra, Andrey Jorge; Prokić, Marko D.; Vasconsuelo, Andrea Anahi; Pinto, José Renato
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Oxidative stress can be considered a consequence ofimbalance in the formation of reactive oxygen species(ROS) and antioxidant defense systems, in which mitochondriaappear to be the main source of ROS production. A keyconcern is that high levels of ROS can modulate molecularand structural modifications and lead to functional changeswithin the muscle. In this regard, ROS causes oxidation ofbiomolecules, in which results in loss of their biologicalfunctions and leads to homeostatic imbalance. The maineffects mediated by ROS relate to its potential to cause oxidativedamage in cells and tissues [1]. Therefore, a ROS burstcontributes to cellular dysfunction and can cause a widerange of chronic diseases. Scientific advances have alloweda better understanding of the role of oxidative stress on muscularhomeostasis; thereby, deciphering and understandinghow ROS regulate specific molecules and processes that alterphysiological function could cause development of pathologies.Thus, studying the effects of ROS could assist with thedevelopment of new therapeutic avenues that address a widerange of muscle disorders.
Fil: Serra, Andrey Jorge. Universidade Nove de Julho; Brasil
Fil: Prokić, Marko D.. University of Belgrade; Serbia
Fil: Vasconsuelo, Andrea Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; Argentina
Fil: Pinto, José Renato. Florida State University; Estados Unidos
Materia
OXIDATIVE STRESS
MUSCLE
PHOTOBIOMODULATION
THERAPY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/91632
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Oxidative Stress in Muscle Diseases: Current and Future TherapySerra, Andrey JorgeProkić, Marko D.Vasconsuelo, Andrea AnahiPinto, José RenatoOXIDATIVE STRESSMUSCLEPHOTOBIOMODULATIONTHERAPYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Oxidative stress can be considered a consequence ofimbalance in the formation of reactive oxygen species(ROS) and antioxidant defense systems, in which mitochondriaappear to be the main source of ROS production. A keyconcern is that high levels of ROS can modulate molecularand structural modifications and lead to functional changeswithin the muscle. In this regard, ROS causes oxidation ofbiomolecules, in which results in loss of their biologicalfunctions and leads to homeostatic imbalance. The maineffects mediated by ROS relate to its potential to cause oxidativedamage in cells and tissues [1]. Therefore, a ROS burstcontributes to cellular dysfunction and can cause a widerange of chronic diseases. Scientific advances have alloweda better understanding of the role of oxidative stress on muscularhomeostasis; thereby, deciphering and understandinghow ROS regulate specific molecules and processes that alterphysiological function could cause development of pathologies.Thus, studying the effects of ROS could assist with thedevelopment of new therapeutic avenues that address a widerange of muscle disorders.Fil: Serra, Andrey Jorge. Universidade Nove de Julho; BrasilFil: Prokić, Marko D.. University of Belgrade; SerbiaFil: Vasconsuelo, Andrea Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaFil: Pinto, José Renato. Florida State University; Estados UnidosLandes Bioscience2018-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/91632Serra, Andrey Jorge; Prokić, Marko D.; Vasconsuelo, Andrea Anahi; Pinto, José Renato; Oxidative Stress in Muscle Diseases: Current and Future Therapy; Landes Bioscience; Oxidative Medicine and Cellular Longevity; 2018; 4-2018; 1-41942-09001942-0994CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/omcl/2018/6439138/info:eu-repo/semantics/altIdentifier/doi/10.1155/2018/6439138info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:22:39Zoai:ri.conicet.gov.ar:11336/91632instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:22:39.273CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Oxidative Stress in Muscle Diseases: Current and Future Therapy
title Oxidative Stress in Muscle Diseases: Current and Future Therapy
spellingShingle Oxidative Stress in Muscle Diseases: Current and Future Therapy
Serra, Andrey Jorge
OXIDATIVE STRESS
MUSCLE
PHOTOBIOMODULATION
THERAPY
title_short Oxidative Stress in Muscle Diseases: Current and Future Therapy
title_full Oxidative Stress in Muscle Diseases: Current and Future Therapy
title_fullStr Oxidative Stress in Muscle Diseases: Current and Future Therapy
title_full_unstemmed Oxidative Stress in Muscle Diseases: Current and Future Therapy
title_sort Oxidative Stress in Muscle Diseases: Current and Future Therapy
dc.creator.none.fl_str_mv Serra, Andrey Jorge
Prokić, Marko D.
Vasconsuelo, Andrea Anahi
Pinto, José Renato
author Serra, Andrey Jorge
author_facet Serra, Andrey Jorge
Prokić, Marko D.
Vasconsuelo, Andrea Anahi
Pinto, José Renato
author_role author
author2 Prokić, Marko D.
Vasconsuelo, Andrea Anahi
Pinto, José Renato
author2_role author
author
author
dc.subject.none.fl_str_mv OXIDATIVE STRESS
MUSCLE
PHOTOBIOMODULATION
THERAPY
topic OXIDATIVE STRESS
MUSCLE
PHOTOBIOMODULATION
THERAPY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Oxidative stress can be considered a consequence ofimbalance in the formation of reactive oxygen species(ROS) and antioxidant defense systems, in which mitochondriaappear to be the main source of ROS production. A keyconcern is that high levels of ROS can modulate molecularand structural modifications and lead to functional changeswithin the muscle. In this regard, ROS causes oxidation ofbiomolecules, in which results in loss of their biologicalfunctions and leads to homeostatic imbalance. The maineffects mediated by ROS relate to its potential to cause oxidativedamage in cells and tissues [1]. Therefore, a ROS burstcontributes to cellular dysfunction and can cause a widerange of chronic diseases. Scientific advances have alloweda better understanding of the role of oxidative stress on muscularhomeostasis; thereby, deciphering and understandinghow ROS regulate specific molecules and processes that alterphysiological function could cause development of pathologies.Thus, studying the effects of ROS could assist with thedevelopment of new therapeutic avenues that address a widerange of muscle disorders.
Fil: Serra, Andrey Jorge. Universidade Nove de Julho; Brasil
Fil: Prokić, Marko D.. University of Belgrade; Serbia
Fil: Vasconsuelo, Andrea Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; Argentina
Fil: Pinto, José Renato. Florida State University; Estados Unidos
description Oxidative stress can be considered a consequence ofimbalance in the formation of reactive oxygen species(ROS) and antioxidant defense systems, in which mitochondriaappear to be the main source of ROS production. A keyconcern is that high levels of ROS can modulate molecularand structural modifications and lead to functional changeswithin the muscle. In this regard, ROS causes oxidation ofbiomolecules, in which results in loss of their biologicalfunctions and leads to homeostatic imbalance. The maineffects mediated by ROS relate to its potential to cause oxidativedamage in cells and tissues [1]. Therefore, a ROS burstcontributes to cellular dysfunction and can cause a widerange of chronic diseases. Scientific advances have alloweda better understanding of the role of oxidative stress on muscularhomeostasis; thereby, deciphering and understandinghow ROS regulate specific molecules and processes that alterphysiological function could cause development of pathologies.Thus, studying the effects of ROS could assist with thedevelopment of new therapeutic avenues that address a widerange of muscle disorders.
publishDate 2018
dc.date.none.fl_str_mv 2018-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/91632
Serra, Andrey Jorge; Prokić, Marko D.; Vasconsuelo, Andrea Anahi; Pinto, José Renato; Oxidative Stress in Muscle Diseases: Current and Future Therapy; Landes Bioscience; Oxidative Medicine and Cellular Longevity; 2018; 4-2018; 1-4
1942-0900
1942-0994
CONICET Digital
CONICET
url http://hdl.handle.net/11336/91632
identifier_str_mv Serra, Andrey Jorge; Prokić, Marko D.; Vasconsuelo, Andrea Anahi; Pinto, José Renato; Oxidative Stress in Muscle Diseases: Current and Future Therapy; Landes Bioscience; Oxidative Medicine and Cellular Longevity; 2018; 4-2018; 1-4
1942-0900
1942-0994
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/omcl/2018/6439138/
info:eu-repo/semantics/altIdentifier/doi/10.1155/2018/6439138
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Landes Bioscience
publisher.none.fl_str_mv Landes Bioscience
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.48226

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