Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions
- Autores
- Ahmed, Muhammad Naeem; Madni, Murtaza; Anjum, Shaista; Andleeb, Saiqa; Hameed, Shahid; Khan, Abdul Majeed; Ashfaq, Muhammad; Tahir, Muhammad Nawaz; Gil, Diego Mauricio; Frontera, Antonio
- Año de publicación
- 2021
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl)ethanone (7), ethyl 2-(5-(4-bromophenyl)-3-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)thiazole-4-carboxylate (8) and 2-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-N′-(2-hydroxy-3-methoxybenzylidene)thiazole-4-carbohydrazide (10) are described in this manuscript. The structure-directing role of a variety of noncovalent interactions has been analyzed energetically using DFT calculations and Hirshfeld surface analysis. Moreover, the existence and importance of halogen and chalcogen bonding interactions have been analyzed by using the quantum theory of atoms in molecules and the noncovalent interaction index (NCIplot).
Fil: Ahmed, Muhammad Naeem. University of Azad Jammu and Kashmir; Pakistán
Fil: Madni, Murtaza. Quaiad-i-Azam University; Pakistán
Fil: Anjum, Shaista. University of Azad Jammu and Kashmir; Pakistán
Fil: Andleeb, Saiqa. University of Azad Jammu and Kashmir; Pakistán
Fil: Hameed, Shahid. Quaiad-i-Azam University; Pakistán
Fil: Khan, Abdul Majeed. Federal Urdu University of Arts; Pakistán. University Road; Pakistán
Fil: Ashfaq, Muhammad. University of Sargodha; Pakistán
Fil: Tahir, Muhammad Nawaz. University of Sargodha; Pakistán
Fil: Gil, Diego Mauricio. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química Orgánica; Argentina
Fil: Frontera, Antonio. Universidad de las Islas Baleares; España - Materia
-
PYRAZOLYL-THIAZOLE
CRYSTAL STRUCTURE
HIRSHFELD SURFACES
DFT - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/148301
Ver los metadatos del registro completo
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CONICET Digital (CONICET) |
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Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactionsAhmed, Muhammad NaeemMadni, MurtazaAnjum, ShaistaAndleeb, SaiqaHameed, ShahidKhan, Abdul MajeedAshfaq, MuhammadTahir, Muhammad NawazGil, Diego MauricioFrontera, AntonioPYRAZOLYL-THIAZOLECRYSTAL STRUCTUREHIRSHFELD SURFACESDFThttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl)ethanone (7), ethyl 2-(5-(4-bromophenyl)-3-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)thiazole-4-carboxylate (8) and 2-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-N′-(2-hydroxy-3-methoxybenzylidene)thiazole-4-carbohydrazide (10) are described in this manuscript. The structure-directing role of a variety of noncovalent interactions has been analyzed energetically using DFT calculations and Hirshfeld surface analysis. Moreover, the existence and importance of halogen and chalcogen bonding interactions have been analyzed by using the quantum theory of atoms in molecules and the noncovalent interaction index (NCIplot).Fil: Ahmed, Muhammad Naeem. University of Azad Jammu and Kashmir; PakistánFil: Madni, Murtaza. Quaiad-i-Azam University; PakistánFil: Anjum, Shaista. University of Azad Jammu and Kashmir; PakistánFil: Andleeb, Saiqa. University of Azad Jammu and Kashmir; PakistánFil: Hameed, Shahid. Quaiad-i-Azam University; PakistánFil: Khan, Abdul Majeed. Federal Urdu University of Arts; Pakistán. University Road; PakistánFil: Ashfaq, Muhammad. University of Sargodha; PakistánFil: Tahir, Muhammad Nawaz. University of Sargodha; PakistánFil: Gil, Diego Mauricio. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química Orgánica; ArgentinaFil: Frontera, Antonio. Universidad de las Islas Baleares; EspañaRoyal Society of Chemistry2021-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/148301Ahmed, Muhammad Naeem; Madni, Murtaza; Anjum, Shaista; Andleeb, Saiqa; Hameed, Shahid; et al.; Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions; Royal Society of Chemistry; CrystEngComm; 23; 18; 3-2021; 3276-32871466-80331466-8033CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1039/D1CE00256Binfo:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/content/articlelanding/2021/CE/D1CE00256Binfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:16:19Zoai:ri.conicet.gov.ar:11336/148301instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:16:20.28CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
title |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
spellingShingle |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions Ahmed, Muhammad Naeem PYRAZOLYL-THIAZOLE CRYSTAL STRUCTURE HIRSHFELD SURFACES DFT |
title_short |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
title_full |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
title_fullStr |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
title_full_unstemmed |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
title_sort |
Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions |
dc.creator.none.fl_str_mv |
Ahmed, Muhammad Naeem Madni, Murtaza Anjum, Shaista Andleeb, Saiqa Hameed, Shahid Khan, Abdul Majeed Ashfaq, Muhammad Tahir, Muhammad Nawaz Gil, Diego Mauricio Frontera, Antonio |
author |
Ahmed, Muhammad Naeem |
author_facet |
Ahmed, Muhammad Naeem Madni, Murtaza Anjum, Shaista Andleeb, Saiqa Hameed, Shahid Khan, Abdul Majeed Ashfaq, Muhammad Tahir, Muhammad Nawaz Gil, Diego Mauricio Frontera, Antonio |
author_role |
author |
author2 |
Madni, Murtaza Anjum, Shaista Andleeb, Saiqa Hameed, Shahid Khan, Abdul Majeed Ashfaq, Muhammad Tahir, Muhammad Nawaz Gil, Diego Mauricio Frontera, Antonio |
author2_role |
author author author author author author author author author |
dc.subject.none.fl_str_mv |
PYRAZOLYL-THIAZOLE CRYSTAL STRUCTURE HIRSHFELD SURFACES DFT |
topic |
PYRAZOLYL-THIAZOLE CRYSTAL STRUCTURE HIRSHFELD SURFACES DFT |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl)ethanone (7), ethyl 2-(5-(4-bromophenyl)-3-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)thiazole-4-carboxylate (8) and 2-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-N′-(2-hydroxy-3-methoxybenzylidene)thiazole-4-carbohydrazide (10) are described in this manuscript. The structure-directing role of a variety of noncovalent interactions has been analyzed energetically using DFT calculations and Hirshfeld surface analysis. Moreover, the existence and importance of halogen and chalcogen bonding interactions have been analyzed by using the quantum theory of atoms in molecules and the noncovalent interaction index (NCIplot). Fil: Ahmed, Muhammad Naeem. University of Azad Jammu and Kashmir; Pakistán Fil: Madni, Murtaza. Quaiad-i-Azam University; Pakistán Fil: Anjum, Shaista. University of Azad Jammu and Kashmir; Pakistán Fil: Andleeb, Saiqa. University of Azad Jammu and Kashmir; Pakistán Fil: Hameed, Shahid. Quaiad-i-Azam University; Pakistán Fil: Khan, Abdul Majeed. Federal Urdu University of Arts; Pakistán. University Road; Pakistán Fil: Ashfaq, Muhammad. University of Sargodha; Pakistán Fil: Tahir, Muhammad Nawaz. University of Sargodha; Pakistán Fil: Gil, Diego Mauricio. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química Orgánica; Argentina Fil: Frontera, Antonio. Universidad de las Islas Baleares; España |
description |
The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl)ethanone (7), ethyl 2-(5-(4-bromophenyl)-3-(4-chlorophenyl)-4,5-dihydropyrazol-1-yl)thiazole-4-carboxylate (8) and 2-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-N′-(2-hydroxy-3-methoxybenzylidene)thiazole-4-carbohydrazide (10) are described in this manuscript. The structure-directing role of a variety of noncovalent interactions has been analyzed energetically using DFT calculations and Hirshfeld surface analysis. Moreover, the existence and importance of halogen and chalcogen bonding interactions have been analyzed by using the quantum theory of atoms in molecules and the noncovalent interaction index (NCIplot). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/148301 Ahmed, Muhammad Naeem; Madni, Murtaza; Anjum, Shaista; Andleeb, Saiqa; Hameed, Shahid; et al.; Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions; Royal Society of Chemistry; CrystEngComm; 23; 18; 3-2021; 3276-3287 1466-8033 1466-8033 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/148301 |
identifier_str_mv |
Ahmed, Muhammad Naeem; Madni, Murtaza; Anjum, Shaista; Andleeb, Saiqa; Hameed, Shahid; et al.; Crystal engineering with pyrazolyl-thiazole derivatives: structure-directing role of π-stacking and σ-hole interactions; Royal Society of Chemistry; CrystEngComm; 23; 18; 3-2021; 3276-3287 1466-8033 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1039/D1CE00256B info:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/content/articlelanding/2021/CE/D1CE00256B |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Royal Society of Chemistry |
publisher.none.fl_str_mv |
Royal Society of Chemistry |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614107430387712 |
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13.070432 |