Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition

Autores
Zeitoune, Angel Alberto; Erbes, Luciana Ariadna; Casco, Victor Hugo; Adur, Javier Fernando
Año de publicación
2018
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Second-harmonic generation microscopy is a new imaging tool that allows analyzing non-centrosymmetric structures, such as collagen. This method can be used to detect structural organization of human ovarian extracellular matrix. Collagen remodeling can be used as early indicator of disease states, such as tumor development and invasiveness. Scoring structural characteristics like main collagen orientation and organization do allow differentiating between healthy and cancerous tissue. In this report, it is proposed a new method to calculate the main orientation angle as well as the degree of collagen fibers organization. The algorithm is based on the analysis of image Fourier transform modulus, characterizing spectral distribution by using singular value decomposition. The preliminary results obtained in this work demonstrate that the method allows to discriminate healthy from cancerous tissue.
Fil: Zeitoune, Angel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Erbes, Luciana Ariadna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Adur, Javier Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Materia
SHG
MICROSCOPÍA
COLAGENO
ORGANIZACIÓN
CÁNCER
SVD
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/87795
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Quantification of Collagen Fiber Orientation and Organization by Singular Value DecompositionZeitoune, Angel AlbertoErbes, Luciana AriadnaCasco, Victor HugoAdur, Javier FernandoSHGMICROSCOPÍACOLAGENOORGANIZACIÓNCÁNCERSVDhttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2Second-harmonic generation microscopy is a new imaging tool that allows analyzing non-centrosymmetric structures, such as collagen. This method can be used to detect structural organization of human ovarian extracellular matrix. Collagen remodeling can be used as early indicator of disease states, such as tumor development and invasiveness. Scoring structural characteristics like main collagen orientation and organization do allow differentiating between healthy and cancerous tissue. In this report, it is proposed a new method to calculate the main orientation angle as well as the degree of collagen fibers organization. The algorithm is based on the analysis of image Fourier transform modulus, characterizing spectral distribution by using singular value decomposition. The preliminary results obtained in this work demonstrate that the method allows to discriminate healthy from cancerous tissue.Fil: Zeitoune, Angel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; ArgentinaFil: Erbes, Luciana Ariadna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; ArgentinaFil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaFil: Adur, Javier Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaSociedad Argentina de Bioingeniería2018-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/87795Zeitoune, Angel Alberto; Erbes, Luciana Ariadna; Casco, Victor Hugo; Adur, Javier Fernando; Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition; Sociedad Argentina de Bioingeniería; Revista Argentina de Bioingeniería; 22; 3; 9-2018; 49-532591-376XCONICET DigitalCONICETspainfo:eu-repo/semantics/altIdentifier/url/http://revistasabi.fi.mdp.edu.ar/index.php/revista/article/view/241info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:54Zoai:ri.conicet.gov.ar:11336/87795instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:54.436CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
title Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
spellingShingle Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
Zeitoune, Angel Alberto
SHG
MICROSCOPÍA
COLAGENO
ORGANIZACIÓN
CÁNCER
SVD
title_short Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
title_full Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
title_fullStr Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
title_full_unstemmed Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
title_sort Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition
dc.creator.none.fl_str_mv Zeitoune, Angel Alberto
Erbes, Luciana Ariadna
Casco, Victor Hugo
Adur, Javier Fernando
author Zeitoune, Angel Alberto
author_facet Zeitoune, Angel Alberto
Erbes, Luciana Ariadna
Casco, Victor Hugo
Adur, Javier Fernando
author_role author
author2 Erbes, Luciana Ariadna
Casco, Victor Hugo
Adur, Javier Fernando
author2_role author
author
author
dc.subject.none.fl_str_mv SHG
MICROSCOPÍA
COLAGENO
ORGANIZACIÓN
CÁNCER
SVD
topic SHG
MICROSCOPÍA
COLAGENO
ORGANIZACIÓN
CÁNCER
SVD
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.6
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Second-harmonic generation microscopy is a new imaging tool that allows analyzing non-centrosymmetric structures, such as collagen. This method can be used to detect structural organization of human ovarian extracellular matrix. Collagen remodeling can be used as early indicator of disease states, such as tumor development and invasiveness. Scoring structural characteristics like main collagen orientation and organization do allow differentiating between healthy and cancerous tissue. In this report, it is proposed a new method to calculate the main orientation angle as well as the degree of collagen fibers organization. The algorithm is based on the analysis of image Fourier transform modulus, characterizing spectral distribution by using singular value decomposition. The preliminary results obtained in this work demonstrate that the method allows to discriminate healthy from cancerous tissue.
Fil: Zeitoune, Angel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Erbes, Luciana Ariadna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Adur, Javier Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
description Second-harmonic generation microscopy is a new imaging tool that allows analyzing non-centrosymmetric structures, such as collagen. This method can be used to detect structural organization of human ovarian extracellular matrix. Collagen remodeling can be used as early indicator of disease states, such as tumor development and invasiveness. Scoring structural characteristics like main collagen orientation and organization do allow differentiating between healthy and cancerous tissue. In this report, it is proposed a new method to calculate the main orientation angle as well as the degree of collagen fibers organization. The algorithm is based on the analysis of image Fourier transform modulus, characterizing spectral distribution by using singular value decomposition. The preliminary results obtained in this work demonstrate that the method allows to discriminate healthy from cancerous tissue.
publishDate 2018
dc.date.none.fl_str_mv 2018-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/87795
Zeitoune, Angel Alberto; Erbes, Luciana Ariadna; Casco, Victor Hugo; Adur, Javier Fernando; Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition; Sociedad Argentina de Bioingeniería; Revista Argentina de Bioingeniería; 22; 3; 9-2018; 49-53
2591-376X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/87795
identifier_str_mv Zeitoune, Angel Alberto; Erbes, Luciana Ariadna; Casco, Victor Hugo; Adur, Javier Fernando; Quantification of Collagen Fiber Orientation and Organization by Singular Value Decomposition; Sociedad Argentina de Bioingeniería; Revista Argentina de Bioingeniería; 22; 3; 9-2018; 49-53
2591-376X
CONICET Digital
CONICET
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://revistasabi.fi.mdp.edu.ar/index.php/revista/article/view/241
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Argentina de Bioingeniería
publisher.none.fl_str_mv Sociedad Argentina de Bioingeniería
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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