Nitro-fatty acid formation and metabolism

Autores
Buchan, Gregory J.; Bonacci, Gustavo Roberto; Fazzari, Marco; Salvatore, Sonia Rosana; Gelhaus Wendell, Stacy
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nitro-fatty acids (NO 2 -FA) are pleiotropic modulators of redox signaling pathways. Their effects on inflammatory signaling have been studied in great detail in cell, animal and clinical models primarily using exogenously administered nitro-oleic acid. While we know a considerable amount regarding NO 2 -FA signaling, endogenous formation and metabolism is relatively unexplored. This review will cover what is currently known regarding the proposed mechanisms of NO 2 -FA formation, dietary modulation of endogenous NO 2 -FA levels, pathways of NO 2 -FA metabolism and the detection of NO 2 -FA and corresponding metabolites.
Fil: Buchan, Gregory J.. University of Pittsburgh; Estados Unidos
Fil: Bonacci, Gustavo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Fazzari, Marco. University of Pittsburgh; Estados Unidos. Fondazione Ri.Med; Italia
Fil: Salvatore, Sonia Rosana. University of Pittsburgh; Estados Unidos
Fil: Gelhaus Wendell, Stacy. University of Pittsburgh; Estados Unidos
Materia
DIET
METABOLISM
NITRATION
NITRIC OXIDE
NITRO-CONJUGATED LINOLEIC ACID
NITRO-FATTY ACID
NITROGEN DIOXIDE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/95849
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Nitro-fatty acid formation and metabolismBuchan, Gregory J.Bonacci, Gustavo RobertoFazzari, MarcoSalvatore, Sonia RosanaGelhaus Wendell, StacyDIETMETABOLISMNITRATIONNITRIC OXIDENITRO-CONJUGATED LINOLEIC ACIDNITRO-FATTY ACIDNITROGEN DIOXIDEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Nitro-fatty acids (NO 2 -FA) are pleiotropic modulators of redox signaling pathways. Their effects on inflammatory signaling have been studied in great detail in cell, animal and clinical models primarily using exogenously administered nitro-oleic acid. While we know a considerable amount regarding NO 2 -FA signaling, endogenous formation and metabolism is relatively unexplored. This review will cover what is currently known regarding the proposed mechanisms of NO 2 -FA formation, dietary modulation of endogenous NO 2 -FA levels, pathways of NO 2 -FA metabolism and the detection of NO 2 -FA and corresponding metabolites.Fil: Buchan, Gregory J.. University of Pittsburgh; Estados UnidosFil: Bonacci, Gustavo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Fazzari, Marco. University of Pittsburgh; Estados Unidos. Fondazione Ri.Med; ItaliaFil: Salvatore, Sonia Rosana. University of Pittsburgh; Estados UnidosFil: Gelhaus Wendell, Stacy. University of Pittsburgh; Estados UnidosAcademic Press Inc Elsevier Science2018-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95849Buchan, Gregory J.; Bonacci, Gustavo Roberto; Fazzari, Marco; Salvatore, Sonia Rosana; Gelhaus Wendell, Stacy; Nitro-fatty acid formation and metabolism; Academic Press Inc Elsevier Science; Nitric Oxide-Biology and Chemistry; 79; 9-2018; 38-441089-8603CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.niox.2018.07.003info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S108986031830064info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241218/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:52:30Zoai:ri.conicet.gov.ar:11336/95849instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:52:31.024CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Nitro-fatty acid formation and metabolism
title Nitro-fatty acid formation and metabolism
spellingShingle Nitro-fatty acid formation and metabolism
Buchan, Gregory J.
DIET
METABOLISM
NITRATION
NITRIC OXIDE
NITRO-CONJUGATED LINOLEIC ACID
NITRO-FATTY ACID
NITROGEN DIOXIDE
title_short Nitro-fatty acid formation and metabolism
title_full Nitro-fatty acid formation and metabolism
title_fullStr Nitro-fatty acid formation and metabolism
title_full_unstemmed Nitro-fatty acid formation and metabolism
title_sort Nitro-fatty acid formation and metabolism
dc.creator.none.fl_str_mv Buchan, Gregory J.
Bonacci, Gustavo Roberto
Fazzari, Marco
Salvatore, Sonia Rosana
Gelhaus Wendell, Stacy
author Buchan, Gregory J.
author_facet Buchan, Gregory J.
Bonacci, Gustavo Roberto
Fazzari, Marco
Salvatore, Sonia Rosana
Gelhaus Wendell, Stacy
author_role author
author2 Bonacci, Gustavo Roberto
Fazzari, Marco
Salvatore, Sonia Rosana
Gelhaus Wendell, Stacy
author2_role author
author
author
author
dc.subject.none.fl_str_mv DIET
METABOLISM
NITRATION
NITRIC OXIDE
NITRO-CONJUGATED LINOLEIC ACID
NITRO-FATTY ACID
NITROGEN DIOXIDE
topic DIET
METABOLISM
NITRATION
NITRIC OXIDE
NITRO-CONJUGATED LINOLEIC ACID
NITRO-FATTY ACID
NITROGEN DIOXIDE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Nitro-fatty acids (NO 2 -FA) are pleiotropic modulators of redox signaling pathways. Their effects on inflammatory signaling have been studied in great detail in cell, animal and clinical models primarily using exogenously administered nitro-oleic acid. While we know a considerable amount regarding NO 2 -FA signaling, endogenous formation and metabolism is relatively unexplored. This review will cover what is currently known regarding the proposed mechanisms of NO 2 -FA formation, dietary modulation of endogenous NO 2 -FA levels, pathways of NO 2 -FA metabolism and the detection of NO 2 -FA and corresponding metabolites.
Fil: Buchan, Gregory J.. University of Pittsburgh; Estados Unidos
Fil: Bonacci, Gustavo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Fazzari, Marco. University of Pittsburgh; Estados Unidos. Fondazione Ri.Med; Italia
Fil: Salvatore, Sonia Rosana. University of Pittsburgh; Estados Unidos
Fil: Gelhaus Wendell, Stacy. University of Pittsburgh; Estados Unidos
description Nitro-fatty acids (NO 2 -FA) are pleiotropic modulators of redox signaling pathways. Their effects on inflammatory signaling have been studied in great detail in cell, animal and clinical models primarily using exogenously administered nitro-oleic acid. While we know a considerable amount regarding NO 2 -FA signaling, endogenous formation and metabolism is relatively unexplored. This review will cover what is currently known regarding the proposed mechanisms of NO 2 -FA formation, dietary modulation of endogenous NO 2 -FA levels, pathways of NO 2 -FA metabolism and the detection of NO 2 -FA and corresponding metabolites.
publishDate 2018
dc.date.none.fl_str_mv 2018-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/95849
Buchan, Gregory J.; Bonacci, Gustavo Roberto; Fazzari, Marco; Salvatore, Sonia Rosana; Gelhaus Wendell, Stacy; Nitro-fatty acid formation and metabolism; Academic Press Inc Elsevier Science; Nitric Oxide-Biology and Chemistry; 79; 9-2018; 38-44
1089-8603
CONICET Digital
CONICET
url http://hdl.handle.net/11336/95849
identifier_str_mv Buchan, Gregory J.; Bonacci, Gustavo Roberto; Fazzari, Marco; Salvatore, Sonia Rosana; Gelhaus Wendell, Stacy; Nitro-fatty acid formation and metabolism; Academic Press Inc Elsevier Science; Nitric Oxide-Biology and Chemistry; 79; 9-2018; 38-44
1089-8603
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.niox.2018.07.003
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S108986031830064
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241218/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academic Press Inc Elsevier Science
publisher.none.fl_str_mv Academic Press Inc Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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