Biological Activities of Castela coccinea Griseb: Extracts

Autores
Campagna, Maria Noel; Ratti, María Soledad; Sciara, Mariela Ines; Garcia Vescovi, Eleonora; Gattuso, Martha Ana; Martínez, María Laura
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infusions of leaf and bark of Castela coccinea Griseb. (Simaroubaceae) were traditionally used against dysentery. In this work, anti-bacterial and antioxidant activity were studied in C. coccinea extracts. The higest DPPH scavenging activity was detected in ethanolic leaf extracts with an IC50= 0.015 mg/ml. Bark ethanolic extracts showed inhibition of lipoperoxidation and free radical scavenging. However, a previous work evidenced that this extract is toxic at a concentration needed to show antioxidant activity. It might be consider that wood could be used instead of bark extract as the first one showing higher scavenging activity (Wood 55 %, Bark 33 % of DPPH scavenging) and good inhibition of lipoperoxidation. It is a very interesting fact the high tannin and mucilage content, which are localized particularly in leaves. The high antioxidant activity and abundant mucilage and tannin contents could justify, at least in part, its popular use.
Fil: Campagna, Maria Noel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Ratti, María Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Sciara, Mariela Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Garcia Vescovi, Eleonora. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Gattuso, Martha Ana. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Martínez, María Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Materia
Antioxidant activity
Castela
Mucilage
Simaroubaceae
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/271657
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Biological Activities of Castela coccinea Griseb: ExtractsCampagna, Maria NoelRatti, María SoledadSciara, Mariela InesGarcia Vescovi, EleonoraGattuso, Martha AnaMartínez, María LauraAntioxidant activityCastelaMucilageSimaroubaceaehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Infusions of leaf and bark of Castela coccinea Griseb. (Simaroubaceae) were traditionally used against dysentery. In this work, anti-bacterial and antioxidant activity were studied in C. coccinea extracts. The higest DPPH scavenging activity was detected in ethanolic leaf extracts with an IC50= 0.015 mg/ml. Bark ethanolic extracts showed inhibition of lipoperoxidation and free radical scavenging. However, a previous work evidenced that this extract is toxic at a concentration needed to show antioxidant activity. It might be consider that wood could be used instead of bark extract as the first one showing higher scavenging activity (Wood 55 %, Bark 33 % of DPPH scavenging) and good inhibition of lipoperoxidation. It is a very interesting fact the high tannin and mucilage content, which are localized particularly in leaves. The high antioxidant activity and abundant mucilage and tannin contents could justify, at least in part, its popular use.Fil: Campagna, Maria Noel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Ratti, María Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Sciara, Mariela Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Garcia Vescovi, Eleonora. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Gattuso, Martha Ana. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaFil: Martínez, María Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; ArgentinaColegio de Farmacéuticos de la Provincia de Buenos Aires2011-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/271657Campagna, Maria Noel; Ratti, María Soledad; Sciara, Mariela Ines; Garcia Vescovi, Eleonora; Gattuso, Martha Ana; et al.; Biological Activities of Castela coccinea Griseb: Extracts; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Acta Farmacéutica Bonaerense; 30; 1; 1-2011; 39-440326-2383CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_6.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:58:00Zoai:ri.conicet.gov.ar:11336/271657instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:58:00.586CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Biological Activities of Castela coccinea Griseb: Extracts
title Biological Activities of Castela coccinea Griseb: Extracts
spellingShingle Biological Activities of Castela coccinea Griseb: Extracts
Campagna, Maria Noel
Antioxidant activity
Castela
Mucilage
Simaroubaceae
title_short Biological Activities of Castela coccinea Griseb: Extracts
title_full Biological Activities of Castela coccinea Griseb: Extracts
title_fullStr Biological Activities of Castela coccinea Griseb: Extracts
title_full_unstemmed Biological Activities of Castela coccinea Griseb: Extracts
title_sort Biological Activities of Castela coccinea Griseb: Extracts
dc.creator.none.fl_str_mv Campagna, Maria Noel
Ratti, María Soledad
Sciara, Mariela Ines
Garcia Vescovi, Eleonora
Gattuso, Martha Ana
Martínez, María Laura
author Campagna, Maria Noel
author_facet Campagna, Maria Noel
Ratti, María Soledad
Sciara, Mariela Ines
Garcia Vescovi, Eleonora
Gattuso, Martha Ana
Martínez, María Laura
author_role author
author2 Ratti, María Soledad
Sciara, Mariela Ines
Garcia Vescovi, Eleonora
Gattuso, Martha Ana
Martínez, María Laura
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Antioxidant activity
Castela
Mucilage
Simaroubaceae
topic Antioxidant activity
Castela
Mucilage
Simaroubaceae
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Infusions of leaf and bark of Castela coccinea Griseb. (Simaroubaceae) were traditionally used against dysentery. In this work, anti-bacterial and antioxidant activity were studied in C. coccinea extracts. The higest DPPH scavenging activity was detected in ethanolic leaf extracts with an IC50= 0.015 mg/ml. Bark ethanolic extracts showed inhibition of lipoperoxidation and free radical scavenging. However, a previous work evidenced that this extract is toxic at a concentration needed to show antioxidant activity. It might be consider that wood could be used instead of bark extract as the first one showing higher scavenging activity (Wood 55 %, Bark 33 % of DPPH scavenging) and good inhibition of lipoperoxidation. It is a very interesting fact the high tannin and mucilage content, which are localized particularly in leaves. The high antioxidant activity and abundant mucilage and tannin contents could justify, at least in part, its popular use.
Fil: Campagna, Maria Noel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Ratti, María Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Sciara, Mariela Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Garcia Vescovi, Eleonora. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Gattuso, Martha Ana. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
Fil: Martínez, María Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina
description Infusions of leaf and bark of Castela coccinea Griseb. (Simaroubaceae) were traditionally used against dysentery. In this work, anti-bacterial and antioxidant activity were studied in C. coccinea extracts. The higest DPPH scavenging activity was detected in ethanolic leaf extracts with an IC50= 0.015 mg/ml. Bark ethanolic extracts showed inhibition of lipoperoxidation and free radical scavenging. However, a previous work evidenced that this extract is toxic at a concentration needed to show antioxidant activity. It might be consider that wood could be used instead of bark extract as the first one showing higher scavenging activity (Wood 55 %, Bark 33 % of DPPH scavenging) and good inhibition of lipoperoxidation. It is a very interesting fact the high tannin and mucilage content, which are localized particularly in leaves. The high antioxidant activity and abundant mucilage and tannin contents could justify, at least in part, its popular use.
publishDate 2011
dc.date.none.fl_str_mv 2011-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/271657
Campagna, Maria Noel; Ratti, María Soledad; Sciara, Mariela Ines; Garcia Vescovi, Eleonora; Gattuso, Martha Ana; et al.; Biological Activities of Castela coccinea Griseb: Extracts; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Acta Farmacéutica Bonaerense; 30; 1; 1-2011; 39-44
0326-2383
CONICET Digital
CONICET
url http://hdl.handle.net/11336/271657
identifier_str_mv Campagna, Maria Noel; Ratti, María Soledad; Sciara, Mariela Ines; Garcia Vescovi, Eleonora; Gattuso, Martha Ana; et al.; Biological Activities of Castela coccinea Griseb: Extracts; Colegio de Farmacéuticos de la Provincia de Buenos Aires; Acta Farmacéutica Bonaerense; 30; 1; 1-2011; 39-44
0326-2383
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_6.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Colegio de Farmacéuticos de la Provincia de Buenos Aires
publisher.none.fl_str_mv Colegio de Farmacéuticos de la Provincia de Buenos Aires
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613732123017216
score 13.070432

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