Phytochemical variability of populations of Aloysia citriodora from Argentina

Autores
Di Leo Lira, Paola Maria del Rosario; Retta, Daiana Sabrina; Van Baren, Catalina Maria; Gorzalczany, Susana Beatriz; Bandoni, Arnaldo Luis
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Aloysia citriodora Palau (Verbenaceae) is one of the most widely used herbs in the Argentine traditional medicine as antispasmodic, sedative and for the treatment of stomachache. Its worldwide use has promoted its cultivation not only in our country but also in several Latin American countries, Europe and Asia. There are official monographs in Argentine (FA) and European Pharmacopoeias (PhEU, as „lemon verbena) for the pharmaceutical quality control. Our working group is devoted to update the respective monograph of the FA, taking in account the detected phytochemical variability of local populations. Parameters for a quality profile of volatile metabolites were previously established [1,2]. At this time we have evaluated the phytochemical variability of several populations using the technique by the European Pharmacopoeia (HPLC), in order to identify the best materials for crops affordable for the pharmaceutical industry. We analyzed 22 populations from 12 regions from Argentina, both in culture and wild materials. Our results show significant differences in the contents of verbascoside: from 0.5 to 4.8%, being 2.5% the minimum accepted value in the PhEu. Other peaks were detected in the HPLC profiles, some of them with similar UV spectra as verbascoside, meanwhile others with polyphenolic UV pattern. Therefore, in vitro assays will be undertaken to determine if the quantity of verbascoside itself affects proportionally the pharmacological activity
Fil: Di Leo Lira, Paola Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Fil: Retta, Daiana Sabrina. Universidad de Buenos Aires; Argentina
Fil: Van Baren, Catalina Maria. Universidad de Buenos Aires; Argentina
Fil: Gorzalczany, Susana Beatriz. Universidad de Buenos Aires; Argentina
Fil: Bandoni, Arnaldo Luis. Universidad de Buenos Aires; Argentina
Materia
Aloysia Citriodora
Essential Oil
Choleretic Activity
Antispasmodic Activity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67629
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/67629
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Phytochemical variability of populations of Aloysia citriodora from ArgentinaDi Leo Lira, Paola Maria del RosarioRetta, Daiana SabrinaVan Baren, Catalina MariaGorzalczany, Susana BeatrizBandoni, Arnaldo LuisAloysia CitriodoraEssential OilCholeretic ActivityAntispasmodic Activityhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Aloysia citriodora Palau (Verbenaceae) is one of the most widely used herbs in the Argentine traditional medicine as antispasmodic, sedative and for the treatment of stomachache. Its worldwide use has promoted its cultivation not only in our country but also in several Latin American countries, Europe and Asia. There are official monographs in Argentine (FA) and European Pharmacopoeias (PhEU, as „lemon verbena) for the pharmaceutical quality control. Our working group is devoted to update the respective monograph of the FA, taking in account the detected phytochemical variability of local populations. Parameters for a quality profile of volatile metabolites were previously established [1,2]. At this time we have evaluated the phytochemical variability of several populations using the technique by the European Pharmacopoeia (HPLC), in order to identify the best materials for crops affordable for the pharmaceutical industry. We analyzed 22 populations from 12 regions from Argentina, both in culture and wild materials. Our results show significant differences in the contents of verbascoside: from 0.5 to 4.8%, being 2.5% the minimum accepted value in the PhEu. Other peaks were detected in the HPLC profiles, some of them with similar UV spectra as verbascoside, meanwhile others with polyphenolic UV pattern. Therefore, in vitro assays will be undertaken to determine if the quantity of verbascoside itself affects proportionally the pharmacological activityFil: Di Leo Lira, Paola Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; ArgentinaFil: Retta, Daiana Sabrina. Universidad de Buenos Aires; ArgentinaFil: Van Baren, Catalina Maria. Universidad de Buenos Aires; ArgentinaFil: Gorzalczany, Susana Beatriz. Universidad de Buenos Aires; ArgentinaFil: Bandoni, Arnaldo Luis. Universidad de Buenos Aires; ArgentinaGeorg Thieme Verlag Kg2010-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67629Di Leo Lira, Paola Maria del Rosario; Retta, Daiana Sabrina; Van Baren, Catalina Maria; Gorzalczany, Susana Beatriz; Bandoni, Arnaldo Luis; Phytochemical variability of populations of Aloysia citriodora from Argentina; Georg Thieme Verlag Kg; Planta Medica; 76; 12; 9-20100032-0943CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1055/s-0030-1264347info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1264347info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:06:34Zoai:ri.conicet.gov.ar:11336/67629instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:06:34.807CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phytochemical variability of populations of Aloysia citriodora from Argentina
title Phytochemical variability of populations of Aloysia citriodora from Argentina
spellingShingle Phytochemical variability of populations of Aloysia citriodora from Argentina
Di Leo Lira, Paola Maria del Rosario
Aloysia Citriodora
Essential Oil
Choleretic Activity
Antispasmodic Activity
title_short Phytochemical variability of populations of Aloysia citriodora from Argentina
title_full Phytochemical variability of populations of Aloysia citriodora from Argentina
title_fullStr Phytochemical variability of populations of Aloysia citriodora from Argentina
title_full_unstemmed Phytochemical variability of populations of Aloysia citriodora from Argentina
title_sort Phytochemical variability of populations of Aloysia citriodora from Argentina
dc.creator.none.fl_str_mv Di Leo Lira, Paola Maria del Rosario
Retta, Daiana Sabrina
Van Baren, Catalina Maria
Gorzalczany, Susana Beatriz
Bandoni, Arnaldo Luis
author Di Leo Lira, Paola Maria del Rosario
author_facet Di Leo Lira, Paola Maria del Rosario
Retta, Daiana Sabrina
Van Baren, Catalina Maria
Gorzalczany, Susana Beatriz
Bandoni, Arnaldo Luis
author_role author
author2 Retta, Daiana Sabrina
Van Baren, Catalina Maria
Gorzalczany, Susana Beatriz
Bandoni, Arnaldo Luis
author2_role author
author
author
author
dc.subject.none.fl_str_mv Aloysia Citriodora
Essential Oil
Choleretic Activity
Antispasmodic Activity
topic Aloysia Citriodora
Essential Oil
Choleretic Activity
Antispasmodic Activity
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Aloysia citriodora Palau (Verbenaceae) is one of the most widely used herbs in the Argentine traditional medicine as antispasmodic, sedative and for the treatment of stomachache. Its worldwide use has promoted its cultivation not only in our country but also in several Latin American countries, Europe and Asia. There are official monographs in Argentine (FA) and European Pharmacopoeias (PhEU, as „lemon verbena) for the pharmaceutical quality control. Our working group is devoted to update the respective monograph of the FA, taking in account the detected phytochemical variability of local populations. Parameters for a quality profile of volatile metabolites were previously established [1,2]. At this time we have evaluated the phytochemical variability of several populations using the technique by the European Pharmacopoeia (HPLC), in order to identify the best materials for crops affordable for the pharmaceutical industry. We analyzed 22 populations from 12 regions from Argentina, both in culture and wild materials. Our results show significant differences in the contents of verbascoside: from 0.5 to 4.8%, being 2.5% the minimum accepted value in the PhEu. Other peaks were detected in the HPLC profiles, some of them with similar UV spectra as verbascoside, meanwhile others with polyphenolic UV pattern. Therefore, in vitro assays will be undertaken to determine if the quantity of verbascoside itself affects proportionally the pharmacological activity
Fil: Di Leo Lira, Paola Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; Argentina
Fil: Retta, Daiana Sabrina. Universidad de Buenos Aires; Argentina
Fil: Van Baren, Catalina Maria. Universidad de Buenos Aires; Argentina
Fil: Gorzalczany, Susana Beatriz. Universidad de Buenos Aires; Argentina
Fil: Bandoni, Arnaldo Luis. Universidad de Buenos Aires; Argentina
description Aloysia citriodora Palau (Verbenaceae) is one of the most widely used herbs in the Argentine traditional medicine as antispasmodic, sedative and for the treatment of stomachache. Its worldwide use has promoted its cultivation not only in our country but also in several Latin American countries, Europe and Asia. There are official monographs in Argentine (FA) and European Pharmacopoeias (PhEU, as „lemon verbena) for the pharmaceutical quality control. Our working group is devoted to update the respective monograph of the FA, taking in account the detected phytochemical variability of local populations. Parameters for a quality profile of volatile metabolites were previously established [1,2]. At this time we have evaluated the phytochemical variability of several populations using the technique by the European Pharmacopoeia (HPLC), in order to identify the best materials for crops affordable for the pharmaceutical industry. We analyzed 22 populations from 12 regions from Argentina, both in culture and wild materials. Our results show significant differences in the contents of verbascoside: from 0.5 to 4.8%, being 2.5% the minimum accepted value in the PhEu. Other peaks were detected in the HPLC profiles, some of them with similar UV spectra as verbascoside, meanwhile others with polyphenolic UV pattern. Therefore, in vitro assays will be undertaken to determine if the quantity of verbascoside itself affects proportionally the pharmacological activity
publishDate 2010
dc.date.none.fl_str_mv 2010-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67629
Di Leo Lira, Paola Maria del Rosario; Retta, Daiana Sabrina; Van Baren, Catalina Maria; Gorzalczany, Susana Beatriz; Bandoni, Arnaldo Luis; Phytochemical variability of populations of Aloysia citriodora from Argentina; Georg Thieme Verlag Kg; Planta Medica; 76; 12; 9-2010
0032-0943
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67629
identifier_str_mv Di Leo Lira, Paola Maria del Rosario; Retta, Daiana Sabrina; Van Baren, Catalina Maria; Gorzalczany, Susana Beatriz; Bandoni, Arnaldo Luis; Phytochemical variability of populations of Aloysia citriodora from Argentina; Georg Thieme Verlag Kg; Planta Medica; 76; 12; 9-2010
0032-0943
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1055/s-0030-1264347
info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1264347
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Georg Thieme Verlag Kg
publisher.none.fl_str_mv Georg Thieme Verlag Kg
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781366309486592
score 12.982451

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