PLAGL1: an important player in diverse pathological processes

Autores
Vega Benedetti A.F.; Saucedo C.N.; Zavattari, Patrizia; Vanni, Roberta; Zugaza, José L.; Parada, Luis Antonio
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The PLAGL1 gene encodes a homonymous zinc finger protein that promotes cell cycle arrest and apoptosis through multiple pathways. The protein has been implicated in metabolic, genetic, and neoplastic illnesses, but the molecular mechanisms by which the protein PLAGL1 participates in such diverse processes remains to be elucidated. In this review, we focus mainly on the molecular biology of PLAGL1 and the relevance of its abnormalities to several pathological processes.
Fil: Vega Benedetti A.F.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
Fil: Saucedo C.N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
Fil: Zavattari, Patrizia. University Of Cagliari;
Fil: Vanni, Roberta. University Of Cagliari;
Fil: Zugaza, José L.. University Of The Basque Country;
Fil: Parada, Luis Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
Materia
Plagl1
Cancer
Diabetes
Tumor Suppressor Gene
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/36190
Acceder
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network_name_str CONICET Digital (CONICET)
spelling PLAGL1: an important player in diverse pathological processesVega Benedetti A.F.Saucedo C.N.Zavattari, PatriziaVanni, RobertaZugaza, José L.Parada, Luis AntonioPlagl1CancerDiabetesTumor Suppressor GeneThe PLAGL1 gene encodes a homonymous zinc finger protein that promotes cell cycle arrest and apoptosis through multiple pathways. The protein has been implicated in metabolic, genetic, and neoplastic illnesses, but the molecular mechanisms by which the protein PLAGL1 participates in such diverse processes remains to be elucidated. In this review, we focus mainly on the molecular biology of PLAGL1 and the relevance of its abnormalities to several pathological processes.Fil: Vega Benedetti A.F.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; ArgentinaFil: Saucedo C.N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; ArgentinaFil: Zavattari, Patrizia. University Of Cagliari;Fil: Vanni, Roberta. University Of Cagliari;Fil: Zugaza, José L.. University Of The Basque Country;Fil: Parada, Luis Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; ArgentinaPolish Academy of Sciences2016-06-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/36190Vega Benedetti A.F.; Saucedo C.N.; Zavattari, Patrizia; Vanni, Roberta; Zugaza, José L.; et al.; PLAGL1: an important player in diverse pathological processes; Polish Academy of Sciences; Journal Of Applied Genetics; 58; 1; 16-6-2016; 71-781234-1983CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pubmed/27311313#info:eu-repo/semantics/altIdentifier/doi/10.1007/s13353-016-0355-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-12T09:36:35Zoai:ri.conicet.gov.ar:11336/36190instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-12 09:36:35.785CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv PLAGL1: an important player in diverse pathological processes
title PLAGL1: an important player in diverse pathological processes
spellingShingle PLAGL1: an important player in diverse pathological processes
Vega Benedetti A.F.
Plagl1
Cancer
Diabetes
Tumor Suppressor Gene
title_short PLAGL1: an important player in diverse pathological processes
title_full PLAGL1: an important player in diverse pathological processes
title_fullStr PLAGL1: an important player in diverse pathological processes
title_full_unstemmed PLAGL1: an important player in diverse pathological processes
title_sort PLAGL1: an important player in diverse pathological processes
dc.creator.none.fl_str_mv Vega Benedetti A.F.
Saucedo C.N.
Zavattari, Patrizia
Vanni, Roberta
Zugaza, José L.
Parada, Luis Antonio
author Vega Benedetti A.F.
author_facet Vega Benedetti A.F.
Saucedo C.N.
Zavattari, Patrizia
Vanni, Roberta
Zugaza, José L.
Parada, Luis Antonio
author_role author
author2 Saucedo C.N.
Zavattari, Patrizia
Vanni, Roberta
Zugaza, José L.
Parada, Luis Antonio
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Plagl1
Cancer
Diabetes
Tumor Suppressor Gene
topic Plagl1
Cancer
Diabetes
Tumor Suppressor Gene
dc.description.none.fl_txt_mv The PLAGL1 gene encodes a homonymous zinc finger protein that promotes cell cycle arrest and apoptosis through multiple pathways. The protein has been implicated in metabolic, genetic, and neoplastic illnesses, but the molecular mechanisms by which the protein PLAGL1 participates in such diverse processes remains to be elucidated. In this review, we focus mainly on the molecular biology of PLAGL1 and the relevance of its abnormalities to several pathological processes.
Fil: Vega Benedetti A.F.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
Fil: Saucedo C.N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
Fil: Zavattari, Patrizia. University Of Cagliari;
Fil: Vanni, Roberta. University Of Cagliari;
Fil: Zugaza, José L.. University Of The Basque Country;
Fil: Parada, Luis Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina
description The PLAGL1 gene encodes a homonymous zinc finger protein that promotes cell cycle arrest and apoptosis through multiple pathways. The protein has been implicated in metabolic, genetic, and neoplastic illnesses, but the molecular mechanisms by which the protein PLAGL1 participates in such diverse processes remains to be elucidated. In this review, we focus mainly on the molecular biology of PLAGL1 and the relevance of its abnormalities to several pathological processes.
publishDate 2016
dc.date.none.fl_str_mv 2016-06-16
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/36190
Vega Benedetti A.F.; Saucedo C.N.; Zavattari, Patrizia; Vanni, Roberta; Zugaza, José L.; et al.; PLAGL1: an important player in diverse pathological processes; Polish Academy of Sciences; Journal Of Applied Genetics; 58; 1; 16-6-2016; 71-78
1234-1983
CONICET Digital
CONICET
url http://hdl.handle.net/11336/36190
identifier_str_mv Vega Benedetti A.F.; Saucedo C.N.; Zavattari, Patrizia; Vanni, Roberta; Zugaza, José L.; et al.; PLAGL1: an important player in diverse pathological processes; Polish Academy of Sciences; Journal Of Applied Genetics; 58; 1; 16-6-2016; 71-78
1234-1983
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pubmed/27311313#
info:eu-repo/semantics/altIdentifier/doi/10.1007/s13353-016-0355-4
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Polish Academy of Sciences
publisher.none.fl_str_mv Polish Academy of Sciences
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.976206

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