Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment

Autores
Miceli, Diego Daniel; Zelarayán, Gabriela S; García, Jorge D; Fernández, Viviana; Ferraris, Sergio
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A 7-year-old spayed female domestic shorthair cat weighing 5kg was referred with polyuria, polydipsia, lethargy, abdominal distension and dermatologic abnormalities. Diabetes mellitus was diagnosed and treatment was started with a diet for diabetic cats and insulin glargine (1IU q12h SC). Hyperadrenocorticism (HAC) was suspected and diagnosed based on clinical signs, increased urinary cortisol:creatinine ratio, lack of suppression on low-dose dexamethasone suppression test and abdominal ultrasonography demonstrating bilateral adrenal enlargement. Oral cabergoline (10μg/kg every other day) was initiated. After the second administration of cabergoline, the cat suffered from clinical hypoglycemia and no longer required insulin. One month after insulin withdrawal, blood work and urine analysis results showed normoglycemia, a normal serum fructosamine concentration (244μmol/l) and normal urine analysis without glycosuria. Diabetic remission persisted until its death 7 months later. In addition, cabergoline treatment was associated with improvement in clinical signs such as lethargy, seborrhea, alopecia and abdominal distension.
Fil: Miceli, Diego Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; Argentina. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
Fil: Zelarayán, Gabriela S. Veterinaria Paraná; Argentina
Fil: García, Jorge D. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; Argentina
Fil: Fernández, Viviana. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
Fil: Ferraris, Sergio. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
Materia
DIABETES MELLITUS REMISSION
FELINE CUSHING SYNDROME
CABERGOLINE
PITUITARY-DEPENDENT HYPERADRECORTICISM
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/140791
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatmentMiceli, Diego DanielZelarayán, Gabriela SGarcía, Jorge DFernández, VivianaFerraris, SergioDIABETES MELLITUS REMISSIONFELINE CUSHING SYNDROMECABERGOLINEPITUITARY-DEPENDENT HYPERADRECORTICISMhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4A 7-year-old spayed female domestic shorthair cat weighing 5kg was referred with polyuria, polydipsia, lethargy, abdominal distension and dermatologic abnormalities. Diabetes mellitus was diagnosed and treatment was started with a diet for diabetic cats and insulin glargine (1IU q12h SC). Hyperadrenocorticism (HAC) was suspected and diagnosed based on clinical signs, increased urinary cortisol:creatinine ratio, lack of suppression on low-dose dexamethasone suppression test and abdominal ultrasonography demonstrating bilateral adrenal enlargement. Oral cabergoline (10μg/kg every other day) was initiated. After the second administration of cabergoline, the cat suffered from clinical hypoglycemia and no longer required insulin. One month after insulin withdrawal, blood work and urine analysis results showed normoglycemia, a normal serum fructosamine concentration (244μmol/l) and normal urine analysis without glycosuria. Diabetic remission persisted until its death 7 months later. In addition, cabergoline treatment was associated with improvement in clinical signs such as lethargy, seborrhea, alopecia and abdominal distension.Fil: Miceli, Diego Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; Argentina. Universidad Maimónides. Centro de Ciencias Veterinarias; ArgentinaFil: Zelarayán, Gabriela S. Veterinaria Paraná; ArgentinaFil: García, Jorge D. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; ArgentinaFil: Fernández, Viviana. Universidad Maimónides. Centro de Ciencias Veterinarias; ArgentinaFil: Ferraris, Sergio. Universidad Maimónides. Centro de Ciencias Veterinarias; ArgentinaSAGE Publications2021-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/140791Miceli, Diego Daniel; Zelarayán, Gabriela S; García, Jorge D; Fernández, Viviana; Ferraris, Sergio; Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment; SAGE Publications; Journal of Feline Medicine and Surgery Open Reports; 7; 2; 6-2021; 1-72055-11692055-1169CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/20551169211029896info:eu-repo/semantics/altIdentifier/doi/10.1177/20551169211029896info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:53:26Zoai:ri.conicet.gov.ar:11336/140791instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:53:26.578CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
title Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
spellingShingle Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
Miceli, Diego Daniel
DIABETES MELLITUS REMISSION
FELINE CUSHING SYNDROME
CABERGOLINE
PITUITARY-DEPENDENT HYPERADRECORTICISM
title_short Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
title_full Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
title_fullStr Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
title_full_unstemmed Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
title_sort Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment
dc.creator.none.fl_str_mv Miceli, Diego Daniel
Zelarayán, Gabriela S
García, Jorge D
Fernández, Viviana
Ferraris, Sergio
author Miceli, Diego Daniel
author_facet Miceli, Diego Daniel
Zelarayán, Gabriela S
García, Jorge D
Fernández, Viviana
Ferraris, Sergio
author_role author
author2 Zelarayán, Gabriela S
García, Jorge D
Fernández, Viviana
Ferraris, Sergio
author2_role author
author
author
author
dc.subject.none.fl_str_mv DIABETES MELLITUS REMISSION
FELINE CUSHING SYNDROME
CABERGOLINE
PITUITARY-DEPENDENT HYPERADRECORTICISM
topic DIABETES MELLITUS REMISSION
FELINE CUSHING SYNDROME
CABERGOLINE
PITUITARY-DEPENDENT HYPERADRECORTICISM
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv A 7-year-old spayed female domestic shorthair cat weighing 5kg was referred with polyuria, polydipsia, lethargy, abdominal distension and dermatologic abnormalities. Diabetes mellitus was diagnosed and treatment was started with a diet for diabetic cats and insulin glargine (1IU q12h SC). Hyperadrenocorticism (HAC) was suspected and diagnosed based on clinical signs, increased urinary cortisol:creatinine ratio, lack of suppression on low-dose dexamethasone suppression test and abdominal ultrasonography demonstrating bilateral adrenal enlargement. Oral cabergoline (10μg/kg every other day) was initiated. After the second administration of cabergoline, the cat suffered from clinical hypoglycemia and no longer required insulin. One month after insulin withdrawal, blood work and urine analysis results showed normoglycemia, a normal serum fructosamine concentration (244μmol/l) and normal urine analysis without glycosuria. Diabetic remission persisted until its death 7 months later. In addition, cabergoline treatment was associated with improvement in clinical signs such as lethargy, seborrhea, alopecia and abdominal distension.
Fil: Miceli, Diego Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; Argentina. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
Fil: Zelarayán, Gabriela S. Veterinaria Paraná; Argentina
Fil: García, Jorge D. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela; Argentina
Fil: Fernández, Viviana. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
Fil: Ferraris, Sergio. Universidad Maimónides. Centro de Ciencias Veterinarias; Argentina
description A 7-year-old spayed female domestic shorthair cat weighing 5kg was referred with polyuria, polydipsia, lethargy, abdominal distension and dermatologic abnormalities. Diabetes mellitus was diagnosed and treatment was started with a diet for diabetic cats and insulin glargine (1IU q12h SC). Hyperadrenocorticism (HAC) was suspected and diagnosed based on clinical signs, increased urinary cortisol:creatinine ratio, lack of suppression on low-dose dexamethasone suppression test and abdominal ultrasonography demonstrating bilateral adrenal enlargement. Oral cabergoline (10μg/kg every other day) was initiated. After the second administration of cabergoline, the cat suffered from clinical hypoglycemia and no longer required insulin. One month after insulin withdrawal, blood work and urine analysis results showed normoglycemia, a normal serum fructosamine concentration (244μmol/l) and normal urine analysis without glycosuria. Diabetic remission persisted until its death 7 months later. In addition, cabergoline treatment was associated with improvement in clinical signs such as lethargy, seborrhea, alopecia and abdominal distension.
publishDate 2021
dc.date.none.fl_str_mv 2021-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/140791
Miceli, Diego Daniel; Zelarayán, Gabriela S; García, Jorge D; Fernández, Viviana; Ferraris, Sergio; Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment; SAGE Publications; Journal of Feline Medicine and Surgery Open Reports; 7; 2; 6-2021; 1-7
2055-1169
2055-1169
CONICET Digital
CONICET
url http://hdl.handle.net/11336/140791
identifier_str_mv Miceli, Diego Daniel; Zelarayán, Gabriela S; García, Jorge D; Fernández, Viviana; Ferraris, Sergio; Diabetes mellitus remission in a cat with hyperadrenocorticism after cabergoline treatment; SAGE Publications; Journal of Feline Medicine and Surgery Open Reports; 7; 2; 6-2021; 1-7
2055-1169
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/20551169211029896
info:eu-repo/semantics/altIdentifier/doi/10.1177/20551169211029896
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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