Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series

Autores
Batista, Pablo Rodrigo; Blanco, Paula Graciela; Gobello, María Cristina
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
To describe the effect of the third-generation gonadotropin-releasing hormone antagonist acyline in the treatment of 4 diestrous bitches with the cystic endometrial hyperplasia-pyometra complex. The 4 bitches were treated with 330. μg/kg of subcutaneous acyline on day 0 and antibiotics, and followed up for 2 weeks. One closed-cervix case showed cervical dilatation 36 hours after treatment, and all the 4 animals showed resolution of clinical signs starting on day 3 posttreatment. Ultrasonographic uterine diameters and luminal contents decreased in the bitches having high progesterone serum concentrations before treatment but not in those with low levels. Serum progesterone importantly decreased from high to basal concentrations in the 3 "ultrasonographically cured" animals. No local or systemic side effects related to the treatment were observed. The gonadotropin-releasing hormone antagonist acyline may have a promising place for the medical treatment of cystic endometrial hyperplasia-pyometra complex in dogs.
Fil: Batista, Pablo Rodrigo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Blanco, Paula Graciela. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gobello, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Acyline
Corpus Luteum
Dog
Gnrh Antagonist
Pyometra
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/53408
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/53408
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case SeriesBatista, Pablo RodrigoBlanco, Paula GracielaGobello, María CristinaAcylineCorpus LuteumDogGnrh AntagonistPyometrahttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4To describe the effect of the third-generation gonadotropin-releasing hormone antagonist acyline in the treatment of 4 diestrous bitches with the cystic endometrial hyperplasia-pyometra complex. The 4 bitches were treated with 330. μg/kg of subcutaneous acyline on day 0 and antibiotics, and followed up for 2 weeks. One closed-cervix case showed cervical dilatation 36 hours after treatment, and all the 4 animals showed resolution of clinical signs starting on day 3 posttreatment. Ultrasonographic uterine diameters and luminal contents decreased in the bitches having high progesterone serum concentrations before treatment but not in those with low levels. Serum progesterone importantly decreased from high to basal concentrations in the 3 "ultrasonographically cured" animals. No local or systemic side effects related to the treatment were observed. The gonadotropin-releasing hormone antagonist acyline may have a promising place for the medical treatment of cystic endometrial hyperplasia-pyometra complex in dogs.Fil: Batista, Pablo Rodrigo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Blanco, Paula Graciela. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gobello, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier Inc2015-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/53408Batista, Pablo Rodrigo; Blanco, Paula Graciela; Gobello, María Cristina; Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series; Elsevier Inc; Topics In Companion Animal Medicine; 30; 1; 3-2015; 25-271938-9736CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1053/j.tcam.2015.01.005info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1938973615000070info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:06:03Zoai:ri.conicet.gov.ar:11336/53408instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:06:04.058CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
title Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
spellingShingle Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
Batista, Pablo Rodrigo
Acyline
Corpus Luteum
Dog
Gnrh Antagonist
Pyometra
title_short Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
title_full Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
title_fullStr Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
title_full_unstemmed Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
title_sort Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series
dc.creator.none.fl_str_mv Batista, Pablo Rodrigo
Blanco, Paula Graciela
Gobello, María Cristina
author Batista, Pablo Rodrigo
author_facet Batista, Pablo Rodrigo
Blanco, Paula Graciela
Gobello, María Cristina
author_role author
author2 Blanco, Paula Graciela
Gobello, María Cristina
author2_role author
author
dc.subject.none.fl_str_mv Acyline
Corpus Luteum
Dog
Gnrh Antagonist
Pyometra
topic Acyline
Corpus Luteum
Dog
Gnrh Antagonist
Pyometra
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv To describe the effect of the third-generation gonadotropin-releasing hormone antagonist acyline in the treatment of 4 diestrous bitches with the cystic endometrial hyperplasia-pyometra complex. The 4 bitches were treated with 330. μg/kg of subcutaneous acyline on day 0 and antibiotics, and followed up for 2 weeks. One closed-cervix case showed cervical dilatation 36 hours after treatment, and all the 4 animals showed resolution of clinical signs starting on day 3 posttreatment. Ultrasonographic uterine diameters and luminal contents decreased in the bitches having high progesterone serum concentrations before treatment but not in those with low levels. Serum progesterone importantly decreased from high to basal concentrations in the 3 "ultrasonographically cured" animals. No local or systemic side effects related to the treatment were observed. The gonadotropin-releasing hormone antagonist acyline may have a promising place for the medical treatment of cystic endometrial hyperplasia-pyometra complex in dogs.
Fil: Batista, Pablo Rodrigo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Blanco, Paula Graciela. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gobello, María Cristina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description To describe the effect of the third-generation gonadotropin-releasing hormone antagonist acyline in the treatment of 4 diestrous bitches with the cystic endometrial hyperplasia-pyometra complex. The 4 bitches were treated with 330. μg/kg of subcutaneous acyline on day 0 and antibiotics, and followed up for 2 weeks. One closed-cervix case showed cervical dilatation 36 hours after treatment, and all the 4 animals showed resolution of clinical signs starting on day 3 posttreatment. Ultrasonographic uterine diameters and luminal contents decreased in the bitches having high progesterone serum concentrations before treatment but not in those with low levels. Serum progesterone importantly decreased from high to basal concentrations in the 3 "ultrasonographically cured" animals. No local or systemic side effects related to the treatment were observed. The gonadotropin-releasing hormone antagonist acyline may have a promising place for the medical treatment of cystic endometrial hyperplasia-pyometra complex in dogs.
publishDate 2015
dc.date.none.fl_str_mv 2015-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/53408
Batista, Pablo Rodrigo; Blanco, Paula Graciela; Gobello, María Cristina; Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series; Elsevier Inc; Topics In Companion Animal Medicine; 30; 1; 3-2015; 25-27
1938-9736
CONICET Digital
CONICET
url http://hdl.handle.net/11336/53408
identifier_str_mv Batista, Pablo Rodrigo; Blanco, Paula Graciela; Gobello, María Cristina; Treatment of Canine Pyometra With the Gonadotropin-Releasing Hormone Antagonist Acyline: A Case Series; Elsevier Inc; Topics In Companion Animal Medicine; 30; 1; 3-2015; 25-27
1938-9736
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1053/j.tcam.2015.01.005
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1938973615000070
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Inc
publisher.none.fl_str_mv Elsevier Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083203703504896
score 12.891075

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