A global analysis of Y-chromosomal haplotype diversity for 23 STR loci
- Autores
- Corach, Daniel; Caputo, Mariela; Marino, Miguel Eduardo; Purps, Josephine; Siegert, Sabine; Willuweit, Sascha; Nagy, Marion; Alves, Cíntia; Salazar, Renato; Angustia, Sheila M. T.; Santos, Lorna H.; Anslinger, Katja; Bayer, Birgit; Ayub, Qasim; Wei, Wei; Xue, Yali; Tyler Smith, Chris; Baeta Bafalluy, Miriam; Martínez Jarreta, Begoña; Egyed, Balazs; Balitzki, Beate; Tschumi, Sibylle; Ballard, David; Syndercombe Court, Denise; Barrantes, Xinia; Bäßler, Gerhard; Berger, Burkhard; Niederstätter, Haral; Parson, Walther; Davis, Carey; Furfuro, Sandra; Locarno, Laura
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Marino, Miguel Eduardo. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Analisis de ADN; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Purps, Josephine. Charité-Universitätsmedizin; Alemania
Fil: Siegert, Sabine. University of Cologne; Alemania
Fil: Willuweit, Sascha. Charité-Universitätsmedizin; Alemania
Fil: Nagy, Marion. Charité-Universitätsmedizin; Alemania
Fil: Alves, Cíntia. Universidad de Porto; Portugal
Fil: Salazar, Renato. Universidad de Porto; Portugal
Fil: Angustia, Sheila M. T.. Philippine National Police Crime Laboratory; Filipinas
Fil: Santos, Lorna H.. Philippine National Police Crime Laboratory; Filipinas
Fil: Anslinger, Katja. Universitat Genzentrum Der Ludwing-maximilians; Alemania
Fil: Bayer, Birgit. Universitat Genzentrum Der Ludwing-maximilians; Alemania
Fil: Ayub, Qasim. The Wellcome Trust Sanger Institute; Reino Unido
Fil: Wei, Wei. The Wellcome Trust Sanger Institute; Reino Unido
Fil: Xue, Yali. The Wellcome Trust Sanger Institute; Reino Unido
Fil: Tyler Smith, Chris. The Wellcome Trust Sanger Institute; Reino Unido
Fil: Baeta Bafalluy, Miriam. Universidad de Zaragoza; España
Fil: Martínez Jarreta, Begoña. Universidad de Zaragoza; España
Fil: Egyed, Balazs. Eotvos University, Budapest; Argentina
Fil: Balitzki, Beate. Universidad de Basilea; Suiza
Fil: Tschumi, Sibylle. Universidad de Basilea; Suiza
Fil: Ballard, David. King; Reino Unido
Fil: Syndercombe Court, Denise. King; Reino Unido
Fil: Barrantes, Xinia. Poder Judicial, Forensic Sciences Department; Costa Rica
Fil: Bäßler, Gerhard. Landeskriminalamt Baden-Württemberg; Alemania
Fil: Berger, Burkhard. Universidad de Innsbruck; Austria
Fil: Niederstätter, Haral. Universidad de Innsbruck; Austria
Fil: Parson, Walther. Universidad de Innsbruck; Austria. University Park; Estados Unidos
Fil: Davis, Carey. Department of Molecular and Medical Genetics; Estados Unidos. Institute of Applied Genetics; Estados Unidos
Fil: Furfuro, Sandra. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; Argentina
Fil: Locarno, Laura. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; Argentina - Materia
-
Gene diversity
Discriminatory power
AMOVA
Population structure
Database - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/16096
Ver los metadatos del registro completo
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A global analysis of Y-chromosomal haplotype diversity for 23 STR lociCorach, DanielCaputo, MarielaMarino, Miguel EduardoPurps, JosephineSiegert, SabineWilluweit, SaschaNagy, MarionAlves, CíntiaSalazar, RenatoAngustia, Sheila M. T.Santos, Lorna H.Anslinger, KatjaBayer, BirgitAyub, QasimWei, WeiXue, YaliTyler Smith, ChrisBaeta Bafalluy, MiriamMartínez Jarreta, BegoñaEgyed, BalazsBalitzki, BeateTschumi, SibylleBallard, DavidSyndercombe Court, DeniseBarrantes, XiniaBäßler, GerhardBerger, BurkhardNiederstätter, HaralParson, WaltherDavis, CareyFurfuro, SandraLocarno, LauraGene diversityDiscriminatory powerAMOVAPopulation structureDatabasehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Marino, Miguel Eduardo. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Analisis de ADN; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Purps, Josephine. Charité-Universitätsmedizin; AlemaniaFil: Siegert, Sabine. University of Cologne; AlemaniaFil: Willuweit, Sascha. Charité-Universitätsmedizin; AlemaniaFil: Nagy, Marion. Charité-Universitätsmedizin; AlemaniaFil: Alves, Cíntia. Universidad de Porto; PortugalFil: Salazar, Renato. Universidad de Porto; PortugalFil: Angustia, Sheila M. T.. Philippine National Police Crime Laboratory; FilipinasFil: Santos, Lorna H.. Philippine National Police Crime Laboratory; FilipinasFil: Anslinger, Katja. Universitat Genzentrum Der Ludwing-maximilians; AlemaniaFil: Bayer, Birgit. Universitat Genzentrum Der Ludwing-maximilians; AlemaniaFil: Ayub, Qasim. The Wellcome Trust Sanger Institute; Reino UnidoFil: Wei, Wei. The Wellcome Trust Sanger Institute; Reino UnidoFil: Xue, Yali. The Wellcome Trust Sanger Institute; Reino UnidoFil: Tyler Smith, Chris. The Wellcome Trust Sanger Institute; Reino UnidoFil: Baeta Bafalluy, Miriam. Universidad de Zaragoza; EspañaFil: Martínez Jarreta, Begoña. Universidad de Zaragoza; EspañaFil: Egyed, Balazs. Eotvos University, Budapest; ArgentinaFil: Balitzki, Beate. Universidad de Basilea; SuizaFil: Tschumi, Sibylle. Universidad de Basilea; SuizaFil: Ballard, David. King; Reino UnidoFil: Syndercombe Court, Denise. King; Reino UnidoFil: Barrantes, Xinia. Poder Judicial, Forensic Sciences Department; Costa RicaFil: Bäßler, Gerhard. Landeskriminalamt Baden-Württemberg; AlemaniaFil: Berger, Burkhard. Universidad de Innsbruck; AustriaFil: Niederstätter, Haral. Universidad de Innsbruck; AustriaFil: Parson, Walther. Universidad de Innsbruck; Austria. University Park; Estados UnidosFil: Davis, Carey. Department of Molecular and Medical Genetics; Estados Unidos. Institute of Applied Genetics; Estados UnidosFil: Furfuro, Sandra. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; ArgentinaFil: Locarno, Laura. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; ArgentinaElsevier Ireland2014-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/16096Corach, Daniel; Caputo, Mariela; Marino, Miguel Eduardo; Purps, Josephine; Siegert, Sabine; et al.; A global analysis of Y-chromosomal haplotype diversity for 23 STR loci; Elsevier Ireland; Forensic Science International: Genetics; 12; 9-2014; 12-231872-4973enginfo:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pubmed/24854874info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1872497314000842info:eu-repo/semantics/altIdentifier/doi/10.1016/j.fsigen.2014.04.008info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:42:06Zoai:ri.conicet.gov.ar:11336/16096instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:42:06.346CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| title |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| spellingShingle |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci Corach, Daniel Gene diversity Discriminatory power AMOVA Population structure Database |
| title_short |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| title_full |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| title_fullStr |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| title_full_unstemmed |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| title_sort |
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci |
| dc.creator.none.fl_str_mv |
Corach, Daniel Caputo, Mariela Marino, Miguel Eduardo Purps, Josephine Siegert, Sabine Willuweit, Sascha Nagy, Marion Alves, Cíntia Salazar, Renato Angustia, Sheila M. T. Santos, Lorna H. Anslinger, Katja Bayer, Birgit Ayub, Qasim Wei, Wei Xue, Yali Tyler Smith, Chris Baeta Bafalluy, Miriam Martínez Jarreta, Begoña Egyed, Balazs Balitzki, Beate Tschumi, Sibylle Ballard, David Syndercombe Court, Denise Barrantes, Xinia Bäßler, Gerhard Berger, Burkhard Niederstätter, Haral Parson, Walther Davis, Carey Furfuro, Sandra Locarno, Laura |
| author |
Corach, Daniel |
| author_facet |
Corach, Daniel Caputo, Mariela Marino, Miguel Eduardo Purps, Josephine Siegert, Sabine Willuweit, Sascha Nagy, Marion Alves, Cíntia Salazar, Renato Angustia, Sheila M. T. Santos, Lorna H. Anslinger, Katja Bayer, Birgit Ayub, Qasim Wei, Wei Xue, Yali Tyler Smith, Chris Baeta Bafalluy, Miriam Martínez Jarreta, Begoña Egyed, Balazs Balitzki, Beate Tschumi, Sibylle Ballard, David Syndercombe Court, Denise Barrantes, Xinia Bäßler, Gerhard Berger, Burkhard Niederstätter, Haral Parson, Walther Davis, Carey Furfuro, Sandra Locarno, Laura |
| author_role |
author |
| author2 |
Caputo, Mariela Marino, Miguel Eduardo Purps, Josephine Siegert, Sabine Willuweit, Sascha Nagy, Marion Alves, Cíntia Salazar, Renato Angustia, Sheila M. T. Santos, Lorna H. Anslinger, Katja Bayer, Birgit Ayub, Qasim Wei, Wei Xue, Yali Tyler Smith, Chris Baeta Bafalluy, Miriam Martínez Jarreta, Begoña Egyed, Balazs Balitzki, Beate Tschumi, Sibylle Ballard, David Syndercombe Court, Denise Barrantes, Xinia Bäßler, Gerhard Berger, Burkhard Niederstätter, Haral Parson, Walther Davis, Carey Furfuro, Sandra Locarno, Laura |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Gene diversity Discriminatory power AMOVA Population structure Database |
| topic |
Gene diversity Discriminatory power AMOVA Population structure Database |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| dc.description.none.fl_txt_mv |
In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent. Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Marino, Miguel Eduardo. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Analisis de ADN; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Purps, Josephine. Charité-Universitätsmedizin; Alemania Fil: Siegert, Sabine. University of Cologne; Alemania Fil: Willuweit, Sascha. Charité-Universitätsmedizin; Alemania Fil: Nagy, Marion. Charité-Universitätsmedizin; Alemania Fil: Alves, Cíntia. Universidad de Porto; Portugal Fil: Salazar, Renato. Universidad de Porto; Portugal Fil: Angustia, Sheila M. T.. Philippine National Police Crime Laboratory; Filipinas Fil: Santos, Lorna H.. Philippine National Police Crime Laboratory; Filipinas Fil: Anslinger, Katja. Universitat Genzentrum Der Ludwing-maximilians; Alemania Fil: Bayer, Birgit. Universitat Genzentrum Der Ludwing-maximilians; Alemania Fil: Ayub, Qasim. The Wellcome Trust Sanger Institute; Reino Unido Fil: Wei, Wei. The Wellcome Trust Sanger Institute; Reino Unido Fil: Xue, Yali. The Wellcome Trust Sanger Institute; Reino Unido Fil: Tyler Smith, Chris. The Wellcome Trust Sanger Institute; Reino Unido Fil: Baeta Bafalluy, Miriam. Universidad de Zaragoza; España Fil: Martínez Jarreta, Begoña. Universidad de Zaragoza; España Fil: Egyed, Balazs. Eotvos University, Budapest; Argentina Fil: Balitzki, Beate. Universidad de Basilea; Suiza Fil: Tschumi, Sibylle. Universidad de Basilea; Suiza Fil: Ballard, David. King; Reino Unido Fil: Syndercombe Court, Denise. King; Reino Unido Fil: Barrantes, Xinia. Poder Judicial, Forensic Sciences Department; Costa Rica Fil: Bäßler, Gerhard. Landeskriminalamt Baden-Württemberg; Alemania Fil: Berger, Burkhard. Universidad de Innsbruck; Austria Fil: Niederstätter, Haral. Universidad de Innsbruck; Austria Fil: Parson, Walther. Universidad de Innsbruck; Austria. University Park; Estados Unidos Fil: Davis, Carey. Department of Molecular and Medical Genetics; Estados Unidos. Institute of Applied Genetics; Estados Unidos Fil: Furfuro, Sandra. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; Argentina Fil: Locarno, Laura. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Laboratorio de Análisis de ADN; Argentina |
| description |
In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-09 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/16096 Corach, Daniel; Caputo, Mariela; Marino, Miguel Eduardo; Purps, Josephine; Siegert, Sabine; et al.; A global analysis of Y-chromosomal haplotype diversity for 23 STR loci; Elsevier Ireland; Forensic Science International: Genetics; 12; 9-2014; 12-23 1872-4973 |
| url |
http://hdl.handle.net/11336/16096 |
| identifier_str_mv |
Corach, Daniel; Caputo, Mariela; Marino, Miguel Eduardo; Purps, Josephine; Siegert, Sabine; et al.; A global analysis of Y-chromosomal haplotype diversity for 23 STR loci; Elsevier Ireland; Forensic Science International: Genetics; 12; 9-2014; 12-23 1872-4973 |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
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info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pubmed/24854874 info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1872497314000842 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.fsigen.2014.04.008 |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by/2.5/ar/ |
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application/pdf application/pdf application/pdf |
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Elsevier Ireland |
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Elsevier Ireland |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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