Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits

Autores
Jiménez Aspee, Felipe; Alberto, Maria Rosa; Quispe, Cristina; Caramantin Soriano, Maria del Pilar; Theoduloz, Cristina; Zampini, Iris Catiana; Isla, Maria Ines; Schmeda Hirschmann, Guillermo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.
Fil: Jiménez Aspee, Felipe. Universidad de Talca; Chile
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Quispe, Cristina. Universidad de Talca; Chile
Fil: Caramantin Soriano, Maria del Pilar. Universidad de Talca; Chile
Fil: Theoduloz, Cristina. Universidad de Talca; Chile
Fil: Zampini, Iris Catiana. Universidad de Talca; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile
Materia
Eulychnia Acida
Cactaceae
Copao
Anti-Inflammatory Capacity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/6740
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/6740
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) FruitsJiménez Aspee, FelipeAlberto, Maria RosaQuispe, CristinaCaramantin Soriano, Maria del PilarTheoduloz, CristinaZampini, Iris CatianaIsla, Maria InesSchmeda Hirschmann, GuillermoEulychnia AcidaCactaceaeCopaoAnti-Inflammatory Capacityhttps://purl.org/becyt/ford/4.4https://purl.org/becyt/ford/4Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.Fil: Jiménez Aspee, Felipe. Universidad de Talca; ChileFil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; ArgentinaFil: Quispe, Cristina. Universidad de Talca; ChileFil: Caramantin Soriano, Maria del Pilar. Universidad de Talca; ChileFil: Theoduloz, Cristina. Universidad de Talca; ChileFil: Zampini, Iris Catiana. Universidad de Talca; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; ArgentinaFil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; ArgentinaFil: Schmeda Hirschmann, Guillermo. Universidad de Talca; ChileSpringer2015-02-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/6740Jiménez Aspee, Felipe; Alberto, Maria Rosa; Quispe, Cristina; Caramantin Soriano, Maria del Pilar; Theoduloz, Cristina; et al.; Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits; Springer; Plant Foods For Human Nutrition; 70; 2; 15-2-2015; 135-1400921-9668enginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11130-015-0468-7info:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/pmid/25682221info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007%2Fs11130-015-0468-7info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T10:35:04Zoai:ri.conicet.gov.ar:11336/6740instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 10:35:04.647CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
title Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
spellingShingle Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
Jiménez Aspee, Felipe
Eulychnia Acida
Cactaceae
Copao
Anti-Inflammatory Capacity
title_short Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
title_full Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
title_fullStr Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
title_full_unstemmed Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
title_sort Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits
dc.creator.none.fl_str_mv Jiménez Aspee, Felipe
Alberto, Maria Rosa
Quispe, Cristina
Caramantin Soriano, Maria del Pilar
Theoduloz, Cristina
Zampini, Iris Catiana
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author Jiménez Aspee, Felipe
author_facet Jiménez Aspee, Felipe
Alberto, Maria Rosa
Quispe, Cristina
Caramantin Soriano, Maria del Pilar
Theoduloz, Cristina
Zampini, Iris Catiana
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author_role author
author2 Alberto, Maria Rosa
Quispe, Cristina
Caramantin Soriano, Maria del Pilar
Theoduloz, Cristina
Zampini, Iris Catiana
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Eulychnia Acida
Cactaceae
Copao
Anti-Inflammatory Capacity
topic Eulychnia Acida
Cactaceae
Copao
Anti-Inflammatory Capacity
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.4
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.
Fil: Jiménez Aspee, Felipe. Universidad de Talca; Chile
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Quispe, Cristina. Universidad de Talca; Chile
Fil: Caramantin Soriano, Maria del Pilar. Universidad de Talca; Chile
Fil: Theoduloz, Cristina. Universidad de Talca; Chile
Fil: Zampini, Iris Catiana. Universidad de Talca; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina
Fil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile
description Copao (Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.
publishDate 2015
dc.date.none.fl_str_mv 2015-02-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/6740
Jiménez Aspee, Felipe; Alberto, Maria Rosa; Quispe, Cristina; Caramantin Soriano, Maria del Pilar; Theoduloz, Cristina; et al.; Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits; Springer; Plant Foods For Human Nutrition; 70; 2; 15-2-2015; 135-140
0921-9668
url http://hdl.handle.net/11336/6740
identifier_str_mv Jiménez Aspee, Felipe; Alberto, Maria Rosa; Quispe, Cristina; Caramantin Soriano, Maria del Pilar; Theoduloz, Cristina; et al.; Anti-Inflammatory Activity of Copao (Eulychnia Acida Phil., Cactaceae) Fruits; Springer; Plant Foods For Human Nutrition; 70; 2; 15-2-2015; 135-140
0921-9668
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s11130-015-0468-7
info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/pmid/25682221
info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007%2Fs11130-015-0468-7
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.121305

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