Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina

Autores
Micheloud, Juan Francisco; Marin, R.; Martínez, A.; Gardner, D. R.; Gimeno, Eduardo Juan
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Several toxic plants produce lysosomal storage of glycoproteins and mainly nervous clinical disorders. A disease caused by the consumption of Astragalus garbancillo var. garbancillo in sheep from northwestern Argentina is described here. The affected animals presented weight loss, listlessness, staggering gait, and ataxia. Histopathological studies revealed cellular vacuolation in several organs, mainly in the central nervous system (CNS). The material accumulated in the cells was positive for lectins LCA (Lens culinaris agglutinin), sWGA (succinyl–Triticum vulgaris agglutinin), and Con A (Concanavalin A). Finally, the presence of toxic levels of swainsonine was detected in composite samples of the plant. Poisoning by Astragalus garbancillo var. garbancillo was characterized as α-mannosidosis of plant origin.
Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina. Universidad Católica de Salta; Argentina
Fil: Marin, R.. Universidad Nacional de Jujuy; Argentina
Fil: Martínez, A.. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche; Argentina
Fil: Gardner, D. R.. United States Department of Agriculture. Agricultural Research Service; Argentina
Fil: Gimeno, Eduardo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
Materia
Northwestern Argentina
Sheep
Swainsonine
Astragalus garbancillo var. garbancillo
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67229
Acceder
id CONICETDig_88708a3b1245d0d316c383a8e53474e2
oai_identifier_str oai:ri.conicet.gov.ar:11336/67229
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern ArgentinaMicheloud, Juan FranciscoMarin, R.Martínez, A.Gardner, D. R.Gimeno, Eduardo JuanNorthwestern ArgentinaSheepSwainsonineAstragalus garbancillo var. garbancillohttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Several toxic plants produce lysosomal storage of glycoproteins and mainly nervous clinical disorders. A disease caused by the consumption of Astragalus garbancillo var. garbancillo in sheep from northwestern Argentina is described here. The affected animals presented weight loss, listlessness, staggering gait, and ataxia. Histopathological studies revealed cellular vacuolation in several organs, mainly in the central nervous system (CNS). The material accumulated in the cells was positive for lectins LCA (Lens culinaris agglutinin), sWGA (succinyl–Triticum vulgaris agglutinin), and Con A (Concanavalin A). Finally, the presence of toxic levels of swainsonine was detected in composite samples of the plant. Poisoning by Astragalus garbancillo var. garbancillo was characterized as α-mannosidosis of plant origin.Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina. Universidad Católica de Salta; ArgentinaFil: Marin, R.. Universidad Nacional de Jujuy; ArgentinaFil: Martínez, A.. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche; ArgentinaFil: Gardner, D. R.. United States Department of Agriculture. Agricultural Research Service; ArgentinaFil: Gimeno, Eduardo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; ArgentinaUnited States Department of Agriculture2017-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67229Micheloud, Juan Francisco; Marin, R.; Martínez, A.; Gardner, D. R.; Gimeno, Eduardo Juan; Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina; United States Department of Agriculture; International Journal of Poisonous Plant Research; 4; 1; 10-2017; 72-792320 86942154-3216CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ars.usda.gov/oc/np/poisonousplants/Fall2017/index/info:eu-repo/semantics/altIdentifier/url/https://www.ars.usda.gov/ARSUserFiles/oc/np/PoisonousPlants/Fall2017/poisoning.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:06:12Zoai:ri.conicet.gov.ar:11336/67229instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:06:12.558CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
title Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
spellingShingle Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
Micheloud, Juan Francisco
Northwestern Argentina
Sheep
Swainsonine
Astragalus garbancillo var. garbancillo
title_short Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
title_full Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
title_fullStr Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
title_full_unstemmed Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
title_sort Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina
dc.creator.none.fl_str_mv Micheloud, Juan Francisco
Marin, R.
Martínez, A.
Gardner, D. R.
Gimeno, Eduardo Juan
author Micheloud, Juan Francisco
author_facet Micheloud, Juan Francisco
Marin, R.
Martínez, A.
Gardner, D. R.
Gimeno, Eduardo Juan
author_role author
author2 Marin, R.
Martínez, A.
Gardner, D. R.
Gimeno, Eduardo Juan
author2_role author
author
author
author
dc.subject.none.fl_str_mv Northwestern Argentina
Sheep
Swainsonine
Astragalus garbancillo var. garbancillo
topic Northwestern Argentina
Sheep
Swainsonine
Astragalus garbancillo var. garbancillo
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Several toxic plants produce lysosomal storage of glycoproteins and mainly nervous clinical disorders. A disease caused by the consumption of Astragalus garbancillo var. garbancillo in sheep from northwestern Argentina is described here. The affected animals presented weight loss, listlessness, staggering gait, and ataxia. Histopathological studies revealed cellular vacuolation in several organs, mainly in the central nervous system (CNS). The material accumulated in the cells was positive for lectins LCA (Lens culinaris agglutinin), sWGA (succinyl–Triticum vulgaris agglutinin), and Con A (Concanavalin A). Finally, the presence of toxic levels of swainsonine was detected in composite samples of the plant. Poisoning by Astragalus garbancillo var. garbancillo was characterized as α-mannosidosis of plant origin.
Fil: Micheloud, Juan Francisco. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Investigación Animal del Chaco Semiárido; Argentina. Universidad Católica de Salta; Argentina
Fil: Marin, R.. Universidad Nacional de Jujuy; Argentina
Fil: Martínez, A.. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche; Argentina
Fil: Gardner, D. R.. United States Department of Agriculture. Agricultural Research Service; Argentina
Fil: Gimeno, Eduardo Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
description Several toxic plants produce lysosomal storage of glycoproteins and mainly nervous clinical disorders. A disease caused by the consumption of Astragalus garbancillo var. garbancillo in sheep from northwestern Argentina is described here. The affected animals presented weight loss, listlessness, staggering gait, and ataxia. Histopathological studies revealed cellular vacuolation in several organs, mainly in the central nervous system (CNS). The material accumulated in the cells was positive for lectins LCA (Lens culinaris agglutinin), sWGA (succinyl–Triticum vulgaris agglutinin), and Con A (Concanavalin A). Finally, the presence of toxic levels of swainsonine was detected in composite samples of the plant. Poisoning by Astragalus garbancillo var. garbancillo was characterized as α-mannosidosis of plant origin.
publishDate 2017
dc.date.none.fl_str_mv 2017-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67229
Micheloud, Juan Francisco; Marin, R.; Martínez, A.; Gardner, D. R.; Gimeno, Eduardo Juan; Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina; United States Department of Agriculture; International Journal of Poisonous Plant Research; 4; 1; 10-2017; 72-79
2320 8694
2154-3216
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67229
identifier_str_mv Micheloud, Juan Francisco; Marin, R.; Martínez, A.; Gardner, D. R.; Gimeno, Eduardo Juan; Poisoning by Astragalus garbancillo var. garbancillo in Sheep in Northwestern Argentina; United States Department of Agriculture; International Journal of Poisonous Plant Research; 4; 1; 10-2017; 72-79
2320 8694
2154-3216
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ars.usda.gov/oc/np/poisonousplants/Fall2017/index/
info:eu-repo/semantics/altIdentifier/url/https://www.ars.usda.gov/ARSUserFiles/oc/np/PoisonousPlants/Fall2017/poisoning.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv United States Department of Agriculture
publisher.none.fl_str_mv United States Department of Agriculture
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613907728039936
score 13.070432

Publicaciones similares