Clinical management of drug-resistant tuberculosis in resource constrained settings

Autores
Palmero, Domingo; Ritacco, Gloria Viviana
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Drug-resistant forms of tuberculosis (TB), particularly multi- and extensively drug-resistant TB, represent an important obstacle to global control of the disease. Recently, new drugs, repurposed drugs, and new drug combinations have been evaluated, with a number showing promise for the treatment of drug-resistant TB. Additionally, a range of methods for accelerating mycobacterial culture, identification, and drug susceptibility testing have been developed, and several in-house and commercial genotyping methods for speeding drug resistance detection have become available. Despite these significant achievements in drug development and diagnostics, drug-resistant TB continues to be difficult to diagnose and treat. Significant international efforts are still needed, especially in the field of clinical and operational research, to translate these encouraging developments into effective patient cure and make them readily available to resource-constrained settings, where they are most needed.
Fil: Palmero, Domingo. Ciudad Autónoma de Buenos Aires. Hospital Dr. F. J. Muñiz; Argentina
Fil: Ritacco, Gloria Viviana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Tuberculosis
Multidrug-Resistant Tuberculosis
Drug-Resistance
Treatment
Low-Resource
Management
Drug Susceptibility Testing
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/27202
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/27202
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Clinical management of drug-resistant tuberculosis in resource constrained settingsPalmero, DomingoRitacco, Gloria VivianaTuberculosisMultidrug-Resistant TuberculosisDrug-ResistanceTreatmentLow-ResourceManagementDrug Susceptibility Testinghttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Drug-resistant forms of tuberculosis (TB), particularly multi- and extensively drug-resistant TB, represent an important obstacle to global control of the disease. Recently, new drugs, repurposed drugs, and new drug combinations have been evaluated, with a number showing promise for the treatment of drug-resistant TB. Additionally, a range of methods for accelerating mycobacterial culture, identification, and drug susceptibility testing have been developed, and several in-house and commercial genotyping methods for speeding drug resistance detection have become available. Despite these significant achievements in drug development and diagnostics, drug-resistant TB continues to be difficult to diagnose and treat. Significant international efforts are still needed, especially in the field of clinical and operational research, to translate these encouraging developments into effective patient cure and make them readily available to resource-constrained settings, where they are most needed.Fil: Palmero, Domingo. Ciudad Autónoma de Buenos Aires. Hospital Dr. F. J. Muñiz; ArgentinaFil: Ritacco, Gloria Viviana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaSage Publications2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/27202Palmero, Domingo; Ritacco, Gloria Viviana; Clinical management of drug-resistant tuberculosis in resource constrained settings; Sage Publications; Clinical Medicine Insights: Therapeutics; 5; 6-2013; 117-1351179-559XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.4137/CMT.S6560info:eu-repo/semantics/altIdentifier/url/http://insights.sagepub.com/clinical-management-of-drug-resistant-tuberculosis-in-resource-constra-article-a3714info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:44:07Zoai:ri.conicet.gov.ar:11336/27202instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:44:07.799CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Clinical management of drug-resistant tuberculosis in resource constrained settings
title Clinical management of drug-resistant tuberculosis in resource constrained settings
spellingShingle Clinical management of drug-resistant tuberculosis in resource constrained settings
Palmero, Domingo
Tuberculosis
Multidrug-Resistant Tuberculosis
Drug-Resistance
Treatment
Low-Resource
Management
Drug Susceptibility Testing
title_short Clinical management of drug-resistant tuberculosis in resource constrained settings
title_full Clinical management of drug-resistant tuberculosis in resource constrained settings
title_fullStr Clinical management of drug-resistant tuberculosis in resource constrained settings
title_full_unstemmed Clinical management of drug-resistant tuberculosis in resource constrained settings
title_sort Clinical management of drug-resistant tuberculosis in resource constrained settings
dc.creator.none.fl_str_mv Palmero, Domingo
Ritacco, Gloria Viviana
author Palmero, Domingo
author_facet Palmero, Domingo
Ritacco, Gloria Viviana
author_role author
author2 Ritacco, Gloria Viviana
author2_role author
dc.subject.none.fl_str_mv Tuberculosis
Multidrug-Resistant Tuberculosis
Drug-Resistance
Treatment
Low-Resource
Management
Drug Susceptibility Testing
topic Tuberculosis
Multidrug-Resistant Tuberculosis
Drug-Resistance
Treatment
Low-Resource
Management
Drug Susceptibility Testing
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Drug-resistant forms of tuberculosis (TB), particularly multi- and extensively drug-resistant TB, represent an important obstacle to global control of the disease. Recently, new drugs, repurposed drugs, and new drug combinations have been evaluated, with a number showing promise for the treatment of drug-resistant TB. Additionally, a range of methods for accelerating mycobacterial culture, identification, and drug susceptibility testing have been developed, and several in-house and commercial genotyping methods for speeding drug resistance detection have become available. Despite these significant achievements in drug development and diagnostics, drug-resistant TB continues to be difficult to diagnose and treat. Significant international efforts are still needed, especially in the field of clinical and operational research, to translate these encouraging developments into effective patient cure and make them readily available to resource-constrained settings, where they are most needed.
Fil: Palmero, Domingo. Ciudad Autónoma de Buenos Aires. Hospital Dr. F. J. Muñiz; Argentina
Fil: Ritacco, Gloria Viviana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Drug-resistant forms of tuberculosis (TB), particularly multi- and extensively drug-resistant TB, represent an important obstacle to global control of the disease. Recently, new drugs, repurposed drugs, and new drug combinations have been evaluated, with a number showing promise for the treatment of drug-resistant TB. Additionally, a range of methods for accelerating mycobacterial culture, identification, and drug susceptibility testing have been developed, and several in-house and commercial genotyping methods for speeding drug resistance detection have become available. Despite these significant achievements in drug development and diagnostics, drug-resistant TB continues to be difficult to diagnose and treat. Significant international efforts are still needed, especially in the field of clinical and operational research, to translate these encouraging developments into effective patient cure and make them readily available to resource-constrained settings, where they are most needed.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/27202
Palmero, Domingo; Ritacco, Gloria Viviana; Clinical management of drug-resistant tuberculosis in resource constrained settings; Sage Publications; Clinical Medicine Insights: Therapeutics; 5; 6-2013; 117-135
1179-559X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/27202
identifier_str_mv Palmero, Domingo; Ritacco, Gloria Viviana; Clinical management of drug-resistant tuberculosis in resource constrained settings; Sage Publications; Clinical Medicine Insights: Therapeutics; 5; 6-2013; 117-135
1179-559X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.4137/CMT.S6560
info:eu-repo/semantics/altIdentifier/url/http://insights.sagepub.com/clinical-management-of-drug-resistant-tuberculosis-in-resource-constra-article-a3714
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sage Publications
publisher.none.fl_str_mv Sage Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083544641699840
score 13.22299

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