Nutrition during pregnancy: Influence on the gut microbiome and fetal development

Autores
Barrientos, Gabriela Laura; Ronchi, Francesca; Conrad, Melanie L.
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Pregnancy is a finely tuned process, with the health and well-being of the developing fetus determined by the metabolic status and dietary intake of the mother. The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.
Fil: Barrientos, Gabriela Laura. Hospital Aleman. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ronchi, Francesca. Freie Universität Berlin; Alemania
Fil: Conrad, Melanie L.. Freie Universität Berlin; Alemania
Materia
DOHAD
FETAL DEVELOPMENT
NUTRITION
PREGNANCY
METABOLITES
MICROBIOME
SHORT-CHAIN FATTY ACID
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/236769
Acceder
id CONICETDig_847f638e10f08a586574378b3c60a336
oai_identifier_str oai:ri.conicet.gov.ar:11336/236769
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Nutrition during pregnancy: Influence on the gut microbiome and fetal developmentBarrientos, Gabriela LauraRonchi, FrancescaConrad, Melanie L.DOHADFETAL DEVELOPMENTNUTRITIONPREGNANCYMETABOLITESMICROBIOMESHORT-CHAIN FATTY ACIDhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Pregnancy is a finely tuned process, with the health and well-being of the developing fetus determined by the metabolic status and dietary intake of the mother. The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.Fil: Barrientos, Gabriela Laura. Hospital Aleman. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ronchi, Francesca. Freie Universität Berlin; AlemaniaFil: Conrad, Melanie L.. Freie Universität Berlin; AlemaniaJohn Wiley & Sons2023-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/236769Barrientos, Gabriela Laura; Ronchi, Francesca; Conrad, Melanie L.; Nutrition during pregnancy: Influence on the gut microbiome and fetal development; John Wiley & Sons; American Journal of Reproductive Immunology; 91; 1; 12-2023; 1-111600-0897CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/aji.13802info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:27:41Zoai:ri.conicet.gov.ar:11336/236769instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:27:41.358CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Nutrition during pregnancy: Influence on the gut microbiome and fetal development
title Nutrition during pregnancy: Influence on the gut microbiome and fetal development
spellingShingle Nutrition during pregnancy: Influence on the gut microbiome and fetal development
Barrientos, Gabriela Laura
DOHAD
FETAL DEVELOPMENT
NUTRITION
PREGNANCY
METABOLITES
MICROBIOME
SHORT-CHAIN FATTY ACID
title_short Nutrition during pregnancy: Influence on the gut microbiome and fetal development
title_full Nutrition during pregnancy: Influence on the gut microbiome and fetal development
title_fullStr Nutrition during pregnancy: Influence on the gut microbiome and fetal development
title_full_unstemmed Nutrition during pregnancy: Influence on the gut microbiome and fetal development
title_sort Nutrition during pregnancy: Influence on the gut microbiome and fetal development
dc.creator.none.fl_str_mv Barrientos, Gabriela Laura
Ronchi, Francesca
Conrad, Melanie L.
author Barrientos, Gabriela Laura
author_facet Barrientos, Gabriela Laura
Ronchi, Francesca
Conrad, Melanie L.
author_role author
author2 Ronchi, Francesca
Conrad, Melanie L.
author2_role author
author
dc.subject.none.fl_str_mv DOHAD
FETAL DEVELOPMENT
NUTRITION
PREGNANCY
METABOLITES
MICROBIOME
SHORT-CHAIN FATTY ACID
topic DOHAD
FETAL DEVELOPMENT
NUTRITION
PREGNANCY
METABOLITES
MICROBIOME
SHORT-CHAIN FATTY ACID
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Pregnancy is a finely tuned process, with the health and well-being of the developing fetus determined by the metabolic status and dietary intake of the mother. The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.
Fil: Barrientos, Gabriela Laura. Hospital Aleman. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ronchi, Francesca. Freie Universität Berlin; Alemania
Fil: Conrad, Melanie L.. Freie Universität Berlin; Alemania
description Pregnancy is a finely tuned process, with the health and well-being of the developing fetus determined by the metabolic status and dietary intake of the mother. The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.
publishDate 2023
dc.date.none.fl_str_mv 2023-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/236769
Barrientos, Gabriela Laura; Ronchi, Francesca; Conrad, Melanie L.; Nutrition during pregnancy: Influence on the gut microbiome and fetal development; John Wiley & Sons; American Journal of Reproductive Immunology; 91; 1; 12-2023; 1-11
1600-0897
CONICET Digital
CONICET
url http://hdl.handle.net/11336/236769
identifier_str_mv Barrientos, Gabriela Laura; Ronchi, Francesca; Conrad, Melanie L.; Nutrition during pregnancy: Influence on the gut microbiome and fetal development; John Wiley & Sons; American Journal of Reproductive Immunology; 91; 1; 12-2023; 1-11
1600-0897
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/aji.13802
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614279098007552
score 13.070432

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