Novel Medical Therapies for Pituitary Tumors

Autores
Theodoropoulou, M.; Labeur, M.; Páez Pereda, Marcelo; Haedo, Mariana Raquel; Perone, Marcelo Javier; Renner, U.; Arzt, Eduardo Simon; Stalla, G.K.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors.
Fil: Theodoropoulou, M.. Max Planck Institute of Psychiatry; Alemania
Fil: Labeur, M.. Max Planck Institute of Psychiatry; Alemania
Fil: Páez Pereda, Marcelo. Max Planck Institute of Psychiatry; Alemania
Fil: Haedo, Mariana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Perone, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Renner, U.. Max Planck Institute of Psychiatry; Alemania
Fil: Arzt, Eduardo Simon. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Stalla, G.K.. Max Planck Institute of Psychiatry; Alemania
Materia
Pituitary
Tumors
Adenomas
Curcumina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/69612
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Novel Medical Therapies for Pituitary TumorsTheodoropoulou, M.Labeur, M.Páez Pereda, MarceloHaedo, Mariana RaquelPerone, Marcelo JavierRenner, U.Arzt, Eduardo SimonStalla, G.K.PituitaryTumorsAdenomasCurcuminahttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors.Fil: Theodoropoulou, M.. Max Planck Institute of Psychiatry; AlemaniaFil: Labeur, M.. Max Planck Institute of Psychiatry; AlemaniaFil: Páez Pereda, Marcelo. Max Planck Institute of Psychiatry; AlemaniaFil: Haedo, Mariana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; ArgentinaFil: Perone, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; ArgentinaFil: Renner, U.. Max Planck Institute of Psychiatry; AlemaniaFil: Arzt, Eduardo Simon. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Stalla, G.K.. Max Planck Institute of Psychiatry; AlemaniaKarger2010-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/69612Theodoropoulou, M.; Labeur, M.; Páez Pereda, Marcelo; Haedo, Mariana Raquel; Perone, Marcelo Javier; et al.; Novel Medical Therapies for Pituitary Tumors; Karger; Frontiers of Hormone Research; 38; 7-2010; 158-1640301-3073CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1159/000318506info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/318506info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:03:22Zoai:ri.conicet.gov.ar:11336/69612instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:03:23.167CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Novel Medical Therapies for Pituitary Tumors
title Novel Medical Therapies for Pituitary Tumors
spellingShingle Novel Medical Therapies for Pituitary Tumors
Theodoropoulou, M.
Pituitary
Tumors
Adenomas
Curcumina
title_short Novel Medical Therapies for Pituitary Tumors
title_full Novel Medical Therapies for Pituitary Tumors
title_fullStr Novel Medical Therapies for Pituitary Tumors
title_full_unstemmed Novel Medical Therapies for Pituitary Tumors
title_sort Novel Medical Therapies for Pituitary Tumors
dc.creator.none.fl_str_mv Theodoropoulou, M.
Labeur, M.
Páez Pereda, Marcelo
Haedo, Mariana Raquel
Perone, Marcelo Javier
Renner, U.
Arzt, Eduardo Simon
Stalla, G.K.
author Theodoropoulou, M.
author_facet Theodoropoulou, M.
Labeur, M.
Páez Pereda, Marcelo
Haedo, Mariana Raquel
Perone, Marcelo Javier
Renner, U.
Arzt, Eduardo Simon
Stalla, G.K.
author_role author
author2 Labeur, M.
Páez Pereda, Marcelo
Haedo, Mariana Raquel
Perone, Marcelo Javier
Renner, U.
Arzt, Eduardo Simon
Stalla, G.K.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Pituitary
Tumors
Adenomas
Curcumina
topic Pituitary
Tumors
Adenomas
Curcumina
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors.
Fil: Theodoropoulou, M.. Max Planck Institute of Psychiatry; Alemania
Fil: Labeur, M.. Max Planck Institute of Psychiatry; Alemania
Fil: Páez Pereda, Marcelo. Max Planck Institute of Psychiatry; Alemania
Fil: Haedo, Mariana Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Perone, Marcelo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina
Fil: Renner, U.. Max Planck Institute of Psychiatry; Alemania
Fil: Arzt, Eduardo Simon. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Stalla, G.K.. Max Planck Institute of Psychiatry; Alemania
description Despite considerable progress, there is still no medical treatment available for some kinds of pituitary tumors, in particular hormone inactive adenomas and corticotroph pituitary tumors. Surgical removal or at least debulking of the tumor is the only option to treat these kinds of tumors apart from rarely applied radiotherapy. Moreover, treatment resistance is present in a considerable proportion of patients bearing pituitary tumors, for which medical treatment regimens are already available (prolactinomas, somatotroph adenomas). Thus, novel or improved medical treatment strategies would be desirable. Here, we summarize preclinical and clinical findings about the hormone and growth-suppressive action of various drugs, which will probably lead to novel future medical treatment concepts for pituitary tumors.
publishDate 2010
dc.date.none.fl_str_mv 2010-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/69612
Theodoropoulou, M.; Labeur, M.; Páez Pereda, Marcelo; Haedo, Mariana Raquel; Perone, Marcelo Javier; et al.; Novel Medical Therapies for Pituitary Tumors; Karger; Frontiers of Hormone Research; 38; 7-2010; 158-164
0301-3073
CONICET Digital
CONICET
url http://hdl.handle.net/11336/69612
identifier_str_mv Theodoropoulou, M.; Labeur, M.; Páez Pereda, Marcelo; Haedo, Mariana Raquel; Perone, Marcelo Javier; et al.; Novel Medical Therapies for Pituitary Tumors; Karger; Frontiers of Hormone Research; 38; 7-2010; 158-164
0301-3073
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1159/000318506
info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/318506
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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