Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)

Autores
Kin, Marta Susana; Giménez, Hugo Daniel; Delgado, Fernando; Samartino, Luis Ernesto; Casanave, Emma Beatriz; Fort, Marcelo
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Brucella suis biovar 1 has the broadest animal host spectrum. Affects domestic animals and wildlife species. The aim of our study was to investigate the pathogenesis of B. suis biovar 1 infection in the armadillo (Chaetophractus villosus) under experimental conditions. One gravid female and three adult males were inoculated with a suspension containing 1×106 CFU/mL (colony-forming units) of B. suis biovar 1 by oral route. In addition, the gravid female and one male received the same suspension by the conjunctival route. A young male and two females not inoculated were kept in contact with the animals inoculated. The animals that tested seropositive were euthanized. All inoculated armadillos showed positive antibody titres 2 weeks post inoculation. Of the three uninoculated animals, one female was seropositive for Brucella infection. Brucella was isolated from the spleen, liver, mesenteric lymph nodes, uterus, testes, and urine. Characteristic histologic lesions were found in the epididymis. These results suggest that armadillos can act as a reservoir for the spread of B. suis infection, and the persistence of Brucella in armadillo tissues constitutes a risk for humans, because of the cultural practice of armadillo meat consumption in rural communities.
Fil: Kin, Marta Susana. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Giménez, Hugo Daniel. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; Argentina
Fil: Delgado, Fernando. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas; Argentina
Fil: Samartino, Luis Ernesto. Facultad de Ciencias Veterinarias ; Universidad Catolica de Cuyo;
Fil: Casanave, Emma Beatriz. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Cátedra de Fisiología Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; Argentina
Fil: Fort, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; Argentina
Materia
ARMADILLO
BRUCELLA SUIS BIOVAR 1
CHAETOPHRACTUS VILLOSUS
EXPERIMENTAL INFECTION
PATHOGENESIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/259334
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/259334
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)Kin, Marta SusanaGiménez, Hugo DanielDelgado, FernandoSamartino, Luis ErnestoCasanave, Emma BeatrizFort, MarceloARMADILLOBRUCELLA SUIS BIOVAR 1CHAETOPHRACTUS VILLOSUSEXPERIMENTAL INFECTIONPATHOGENESIShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Brucella suis biovar 1 has the broadest animal host spectrum. Affects domestic animals and wildlife species. The aim of our study was to investigate the pathogenesis of B. suis biovar 1 infection in the armadillo (Chaetophractus villosus) under experimental conditions. One gravid female and three adult males were inoculated with a suspension containing 1×106 CFU/mL (colony-forming units) of B. suis biovar 1 by oral route. In addition, the gravid female and one male received the same suspension by the conjunctival route. A young male and two females not inoculated were kept in contact with the animals inoculated. The animals that tested seropositive were euthanized. All inoculated armadillos showed positive antibody titres 2 weeks post inoculation. Of the three uninoculated animals, one female was seropositive for Brucella infection. Brucella was isolated from the spleen, liver, mesenteric lymph nodes, uterus, testes, and urine. Characteristic histologic lesions were found in the epididymis. These results suggest that armadillos can act as a reservoir for the spread of B. suis infection, and the persistence of Brucella in armadillo tissues constitutes a risk for humans, because of the cultural practice of armadillo meat consumption in rural communities.Fil: Kin, Marta Susana. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Giménez, Hugo Daniel. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; ArgentinaFil: Delgado, Fernando. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas; ArgentinaFil: Samartino, Luis Ernesto. Facultad de Ciencias Veterinarias ; Universidad Catolica de Cuyo;Fil: Casanave, Emma Beatriz. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Cátedra de Fisiología Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaFil: Fort, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; ArgentinaIst Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m2024-08-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/259334Kin, Marta Susana; Giménez, Hugo Daniel; Delgado, Fernando; Samartino, Luis Ernesto; Casanave, Emma Beatriz; et al.; Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus); Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m; Veterinaria Italiana; 60; 3; 9-8-2024; 1 - 80505-401X1828-1427CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.veterinariaitaliana.izs.it/index.php/VetIt/article/view/3007info:eu-repo/semantics/altIdentifier/doi/10.12834/VetIt.3007.25510.2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:47Zoai:ri.conicet.gov.ar:11336/259334instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:48.098CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
title Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
spellingShingle Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
Kin, Marta Susana
ARMADILLO
BRUCELLA SUIS BIOVAR 1
CHAETOPHRACTUS VILLOSUS
EXPERIMENTAL INFECTION
PATHOGENESIS
title_short Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
title_full Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
title_fullStr Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
title_full_unstemmed Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
title_sort Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus)
dc.creator.none.fl_str_mv Kin, Marta Susana
Giménez, Hugo Daniel
Delgado, Fernando
Samartino, Luis Ernesto
Casanave, Emma Beatriz
Fort, Marcelo
author Kin, Marta Susana
author_facet Kin, Marta Susana
Giménez, Hugo Daniel
Delgado, Fernando
Samartino, Luis Ernesto
Casanave, Emma Beatriz
Fort, Marcelo
author_role author
author2 Giménez, Hugo Daniel
Delgado, Fernando
Samartino, Luis Ernesto
Casanave, Emma Beatriz
Fort, Marcelo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ARMADILLO
BRUCELLA SUIS BIOVAR 1
CHAETOPHRACTUS VILLOSUS
EXPERIMENTAL INFECTION
PATHOGENESIS
topic ARMADILLO
BRUCELLA SUIS BIOVAR 1
CHAETOPHRACTUS VILLOSUS
EXPERIMENTAL INFECTION
PATHOGENESIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Brucella suis biovar 1 has the broadest animal host spectrum. Affects domestic animals and wildlife species. The aim of our study was to investigate the pathogenesis of B. suis biovar 1 infection in the armadillo (Chaetophractus villosus) under experimental conditions. One gravid female and three adult males were inoculated with a suspension containing 1×106 CFU/mL (colony-forming units) of B. suis biovar 1 by oral route. In addition, the gravid female and one male received the same suspension by the conjunctival route. A young male and two females not inoculated were kept in contact with the animals inoculated. The animals that tested seropositive were euthanized. All inoculated armadillos showed positive antibody titres 2 weeks post inoculation. Of the three uninoculated animals, one female was seropositive for Brucella infection. Brucella was isolated from the spleen, liver, mesenteric lymph nodes, uterus, testes, and urine. Characteristic histologic lesions were found in the epididymis. These results suggest that armadillos can act as a reservoir for the spread of B. suis infection, and the persistence of Brucella in armadillo tissues constitutes a risk for humans, because of the cultural practice of armadillo meat consumption in rural communities.
Fil: Kin, Marta Susana. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Giménez, Hugo Daniel. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; Argentina
Fil: Delgado, Fernando. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas; Argentina
Fil: Samartino, Luis Ernesto. Facultad de Ciencias Veterinarias ; Universidad Catolica de Cuyo;
Fil: Casanave, Emma Beatriz. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Cátedra de Fisiología Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; Argentina
Fil: Fort, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional La Pampa-San Luis. Estación Experimental Agropecuaria Anguil; Argentina
description Brucella suis biovar 1 has the broadest animal host spectrum. Affects domestic animals and wildlife species. The aim of our study was to investigate the pathogenesis of B. suis biovar 1 infection in the armadillo (Chaetophractus villosus) under experimental conditions. One gravid female and three adult males were inoculated with a suspension containing 1×106 CFU/mL (colony-forming units) of B. suis biovar 1 by oral route. In addition, the gravid female and one male received the same suspension by the conjunctival route. A young male and two females not inoculated were kept in contact with the animals inoculated. The animals that tested seropositive were euthanized. All inoculated armadillos showed positive antibody titres 2 weeks post inoculation. Of the three uninoculated animals, one female was seropositive for Brucella infection. Brucella was isolated from the spleen, liver, mesenteric lymph nodes, uterus, testes, and urine. Characteristic histologic lesions were found in the epididymis. These results suggest that armadillos can act as a reservoir for the spread of B. suis infection, and the persistence of Brucella in armadillo tissues constitutes a risk for humans, because of the cultural practice of armadillo meat consumption in rural communities.
publishDate 2024
dc.date.none.fl_str_mv 2024-08-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/259334
Kin, Marta Susana; Giménez, Hugo Daniel; Delgado, Fernando; Samartino, Luis Ernesto; Casanave, Emma Beatriz; et al.; Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus); Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m; Veterinaria Italiana; 60; 3; 9-8-2024; 1 - 8
0505-401X
1828-1427
CONICET Digital
CONICET
url http://hdl.handle.net/11336/259334
identifier_str_mv Kin, Marta Susana; Giménez, Hugo Daniel; Delgado, Fernando; Samartino, Luis Ernesto; Casanave, Emma Beatriz; et al.; Pathogenesis of Brucella suis biovar 1 in the armadillo (Chaetophractus villosus); Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m; Veterinaria Italiana; 60; 3; 9-8-2024; 1 - 8
0505-401X
1828-1427
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.veterinariaitaliana.izs.it/index.php/VetIt/article/view/3007
info:eu-repo/semantics/altIdentifier/doi/10.12834/VetIt.3007.25510.2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m
publisher.none.fl_str_mv Ist Zooprofilattico Sperimentale Abruzzo & Molise G Caporale-izs A&m
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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