Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)
- Autores
- Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; Piezzi, Ramon Salvador; Scardapane, Luis A.
- Año de publicación
- 2013
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season.
Fil: Rodriguez, Hugo. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
Fil: Penissi, Alicia Beatriz. Universidad Nacional de Cuyo. Facultad de Cs.medicas. Instituto de Histologia y Embriologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Fogal, Teresa Hilda. Universidad Nacional de Cuyo; Argentina
Fil: Dominguez, Susana. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Area Ecológica; Argentina
Fil: Piezzi, Ramon Salvador. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo; Argentina
Fil: Scardapane, Luis A.. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina - Materia
-
Adrenal
Medulla
Epinephrine
Chromaffin - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/7564
Ver los metadatos del registro completo
id |
CONICETDig_77beb123ed59ea5f32d1fd625e665b7e |
---|---|
oai_identifier_str |
oai:ri.conicet.gov.ar:11336/7564 |
network_acronym_str |
CONICETDig |
repository_id_str |
3498 |
network_name_str |
CONICET Digital (CONICET) |
spelling |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus)Rodriguez, HugoFilippa, Veronica PalmiraPenissi, Alicia BeatrizFogal, Teresa HildaDominguez, SusanaPiezzi, Ramon SalvadorScardapane, Luis A.AdrenalMedullaEpinephrineChromaffinhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season.Fil: Rodriguez, Hugo. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Penissi, Alicia Beatriz. Universidad Nacional de Cuyo. Facultad de Cs.medicas. Instituto de Histologia y Embriologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fogal, Teresa Hilda. Universidad Nacional de Cuyo; ArgentinaFil: Dominguez, Susana. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Area Ecológica; ArgentinaFil: Piezzi, Ramon Salvador. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo; ArgentinaFil: Scardapane, Luis A.. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaWiley2013-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/7564Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-10951932-8486enginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ar.22707/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1002/ar.22707info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:19Zoai:ri.conicet.gov.ar:11336/7564instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:19.893CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
title |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
spellingShingle |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) Rodriguez, Hugo Adrenal Medulla Epinephrine Chromaffin |
title_short |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
title_full |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
title_fullStr |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
title_full_unstemmed |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
title_sort |
Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus) |
dc.creator.none.fl_str_mv |
Rodriguez, Hugo Filippa, Veronica Palmira Penissi, Alicia Beatriz Fogal, Teresa Hilda Dominguez, Susana Piezzi, Ramon Salvador Scardapane, Luis A. |
author |
Rodriguez, Hugo |
author_facet |
Rodriguez, Hugo Filippa, Veronica Palmira Penissi, Alicia Beatriz Fogal, Teresa Hilda Dominguez, Susana Piezzi, Ramon Salvador Scardapane, Luis A. |
author_role |
author |
author2 |
Filippa, Veronica Palmira Penissi, Alicia Beatriz Fogal, Teresa Hilda Dominguez, Susana Piezzi, Ramon Salvador Scardapane, Luis A. |
author2_role |
author author author author author author |
dc.subject.none.fl_str_mv |
Adrenal Medulla Epinephrine Chromaffin |
topic |
Adrenal Medulla Epinephrine Chromaffin |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season. Fil: Rodriguez, Hugo. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina Fil: Penissi, Alicia Beatriz. Universidad Nacional de Cuyo. Facultad de Cs.medicas. Instituto de Histologia y Embriologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Fogal, Teresa Hilda. Universidad Nacional de Cuyo; Argentina Fil: Dominguez, Susana. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Area Ecológica; Argentina Fil: Piezzi, Ramon Salvador. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Cuyo; Argentina Fil: Scardapane, Luis A.. Universidad Nacional de San Luis. Facultad de Quimica, Bioquimica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina |
description |
Animals living in nontropical climates modify their physiology and behavior to adapt to seasonal environmental changes. Part of this adaptation involves the release of catecholamine from sympathetic nerve endings and the adrenal medulla, which play a major role in regulating energy balance. The aim of this work was to investigate whether adult male viscachas in their natural habitat exhibits structural changes in the adrenal medulla during the annual seasonal cycle. In August-September, chromaffin granules revealed ultrastructural changes suggestive of piecemeal degranulation. Quantitative morphometric analysis by transmission electron microscopy showed a significantly lower percentage of resting chromaffin granules and a higher percentage of altered granules and empty containers in August-September (late winter) compared to February-March (late summer), suggesting an increased secretory process of catecholamines in August-September. The mechanism of piecemeal degranulation might amplify this process, encouraging the adaptive response to winter environmental conditions. Tissue levels of epinephrine, norepinephrine, and dopamine (analyzed by high-performance liquid chromatography) changed throughout the year, reaching maximum values in February-March and minimum values in August-September. These results demonstrate morphological and biochemical seasonal variations of the adrenal medulla, suggesting that epinephrine might promote energy mobilization, which allow the Lagostomus to cope with adverse environmental conditions and thus to survive during winter season. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-04 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/7564 Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-1095 1932-8486 |
url |
http://hdl.handle.net/11336/7564 |
identifier_str_mv |
Rodriguez, Hugo; Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Fogal, Teresa Hilda; Dominguez, Susana; et al.; Seasonal changes in the activity of the adrenal medulla of viscacha (Lagostomus maximus maximus); Wiley; Anatomical Record-advances In Integrative Anatomy And Evolutionary Biology; 296; 7; 4-2013; 1089-1095 1932-8486 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ar.22707/abstract info:eu-repo/semantics/altIdentifier/doi/10.1002/ar.22707 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1844613447510130688 |
score |
13.070432 |