Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated inte...
- Autores
- Mohammadi, Ghobad; Rashidi, Khodabakhsh; Mahmoudi, Majid; Goicoechea, Hector Casimiro; Jalalvand, Ali R.
- Año de publicación
- 2018
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In this work, we are going to develop an efficient electroanalytical methodology based on generation of second-order differential pulse voltammetric (DPV) data at different pulse heights to exploit second-order advantage for simultaneous determination of levodopa (LDP), carbidopa (CDP), methyldopa (MDP), benserazide (BA), tolcapone (TOL) and entacapone (ENT) in the presence of dopamine (DPA) as uncalibrated interference. The recorded data were baseline- and potential shift-corrected by asymmetric least square spline regression (AsLSSR) and correlation optimized warping (COW) algorithms, respectively. After data pre-processing, multivariate curve resolution-alternating least squares (MCR-ALS) and parallel factor analysis 2 (PARAFAC2) were used to develop three-way calibration models and then, the abilities of the developed models to predict analytes’ concentrations in the absence and presence of DPA were examined in validation and test sets, respectively. MCR-ALS acted better than PARAFAC2 to predict analytes’ concentrations in the absence and presence of DPA as uncalibrated interference. Therefore, MCR-ALS was chosen to predict antiparkinson agents’ concentrations in spiked human serum samples as real cases. Fortunately, acceptable results were obtained which were comparable to those obtained by high performance liquid chromatography with UV detection (HPLC-UV) as reference method.
Fil: Mohammadi, Ghobad. Kermanshah University of Medical Sciences; Irán
Fil: Rashidi, Khodabakhsh. Kermanshah University of Medical Sciences; Irán
Fil: Mahmoudi, Majid. Kermanshah University of Medical Sciences; Irán
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Jalalvand, Ali R.. Kermanshah University of Medical Sciences; Irán - Materia
-
Antiparkinson agents
Simultaneous determination
Multi-way calibration
Second-order advantage
Uncalibrated interference - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/89418
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Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interferenceMohammadi, GhobadRashidi, KhodabakhshMahmoudi, MajidGoicoechea, Hector CasimiroJalalvand, Ali R.Antiparkinson agentsSimultaneous determinationMulti-way calibrationSecond-order advantageUncalibrated interferencehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In this work, we are going to develop an efficient electroanalytical methodology based on generation of second-order differential pulse voltammetric (DPV) data at different pulse heights to exploit second-order advantage for simultaneous determination of levodopa (LDP), carbidopa (CDP), methyldopa (MDP), benserazide (BA), tolcapone (TOL) and entacapone (ENT) in the presence of dopamine (DPA) as uncalibrated interference. The recorded data were baseline- and potential shift-corrected by asymmetric least square spline regression (AsLSSR) and correlation optimized warping (COW) algorithms, respectively. After data pre-processing, multivariate curve resolution-alternating least squares (MCR-ALS) and parallel factor analysis 2 (PARAFAC2) were used to develop three-way calibration models and then, the abilities of the developed models to predict analytes’ concentrations in the absence and presence of DPA were examined in validation and test sets, respectively. MCR-ALS acted better than PARAFAC2 to predict analytes’ concentrations in the absence and presence of DPA as uncalibrated interference. Therefore, MCR-ALS was chosen to predict antiparkinson agents’ concentrations in spiked human serum samples as real cases. Fortunately, acceptable results were obtained which were comparable to those obtained by high performance liquid chromatography with UV detection (HPLC-UV) as reference method.Fil: Mohammadi, Ghobad. Kermanshah University of Medical Sciences; IránFil: Rashidi, Khodabakhsh. Kermanshah University of Medical Sciences; IránFil: Mahmoudi, Majid. Kermanshah University of Medical Sciences; IránFil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Jalalvand, Ali R.. Kermanshah University of Medical Sciences; IránElsevier Science2018-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/89418Mohammadi, Ghobad; Rashidi, Khodabakhsh; Mahmoudi, Majid; Goicoechea, Hector Casimiro; Jalalvand, Ali R.; Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference; Elsevier Science; Journal Of The Taiwan Institute Of Chemical Engineers; 88; 7-2018; 49-611876-1070CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://linkinghub.elsevier.com/retrieve/pii/S1876107018302189info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jtice.2018.04.007info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:38:42Zoai:ri.conicet.gov.ar:11336/89418instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:38:42.335CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
title |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
spellingShingle |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference Mohammadi, Ghobad Antiparkinson agents Simultaneous determination Multi-way calibration Second-order advantage Uncalibrated interference |
title_short |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
title_full |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
title_fullStr |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
title_full_unstemmed |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
title_sort |
Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference |
dc.creator.none.fl_str_mv |
Mohammadi, Ghobad Rashidi, Khodabakhsh Mahmoudi, Majid Goicoechea, Hector Casimiro Jalalvand, Ali R. |
author |
Mohammadi, Ghobad |
author_facet |
Mohammadi, Ghobad Rashidi, Khodabakhsh Mahmoudi, Majid Goicoechea, Hector Casimiro Jalalvand, Ali R. |
author_role |
author |
author2 |
Rashidi, Khodabakhsh Mahmoudi, Majid Goicoechea, Hector Casimiro Jalalvand, Ali R. |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
Antiparkinson agents Simultaneous determination Multi-way calibration Second-order advantage Uncalibrated interference |
topic |
Antiparkinson agents Simultaneous determination Multi-way calibration Second-order advantage Uncalibrated interference |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
In this work, we are going to develop an efficient electroanalytical methodology based on generation of second-order differential pulse voltammetric (DPV) data at different pulse heights to exploit second-order advantage for simultaneous determination of levodopa (LDP), carbidopa (CDP), methyldopa (MDP), benserazide (BA), tolcapone (TOL) and entacapone (ENT) in the presence of dopamine (DPA) as uncalibrated interference. The recorded data were baseline- and potential shift-corrected by asymmetric least square spline regression (AsLSSR) and correlation optimized warping (COW) algorithms, respectively. After data pre-processing, multivariate curve resolution-alternating least squares (MCR-ALS) and parallel factor analysis 2 (PARAFAC2) were used to develop three-way calibration models and then, the abilities of the developed models to predict analytes’ concentrations in the absence and presence of DPA were examined in validation and test sets, respectively. MCR-ALS acted better than PARAFAC2 to predict analytes’ concentrations in the absence and presence of DPA as uncalibrated interference. Therefore, MCR-ALS was chosen to predict antiparkinson agents’ concentrations in spiked human serum samples as real cases. Fortunately, acceptable results were obtained which were comparable to those obtained by high performance liquid chromatography with UV detection (HPLC-UV) as reference method. Fil: Mohammadi, Ghobad. Kermanshah University of Medical Sciences; Irán Fil: Rashidi, Khodabakhsh. Kermanshah University of Medical Sciences; Irán Fil: Mahmoudi, Majid. Kermanshah University of Medical Sciences; Irán Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina Fil: Jalalvand, Ali R.. Kermanshah University of Medical Sciences; Irán |
description |
In this work, we are going to develop an efficient electroanalytical methodology based on generation of second-order differential pulse voltammetric (DPV) data at different pulse heights to exploit second-order advantage for simultaneous determination of levodopa (LDP), carbidopa (CDP), methyldopa (MDP), benserazide (BA), tolcapone (TOL) and entacapone (ENT) in the presence of dopamine (DPA) as uncalibrated interference. The recorded data were baseline- and potential shift-corrected by asymmetric least square spline regression (AsLSSR) and correlation optimized warping (COW) algorithms, respectively. After data pre-processing, multivariate curve resolution-alternating least squares (MCR-ALS) and parallel factor analysis 2 (PARAFAC2) were used to develop three-way calibration models and then, the abilities of the developed models to predict analytes’ concentrations in the absence and presence of DPA were examined in validation and test sets, respectively. MCR-ALS acted better than PARAFAC2 to predict analytes’ concentrations in the absence and presence of DPA as uncalibrated interference. Therefore, MCR-ALS was chosen to predict antiparkinson agents’ concentrations in spiked human serum samples as real cases. Fortunately, acceptable results were obtained which were comparable to those obtained by high performance liquid chromatography with UV detection (HPLC-UV) as reference method. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/89418 Mohammadi, Ghobad; Rashidi, Khodabakhsh; Mahmoudi, Majid; Goicoechea, Hector Casimiro; Jalalvand, Ali R.; Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference; Elsevier Science; Journal Of The Taiwan Institute Of Chemical Engineers; 88; 7-2018; 49-61 1876-1070 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/89418 |
identifier_str_mv |
Mohammadi, Ghobad; Rashidi, Khodabakhsh; Mahmoudi, Majid; Goicoechea, Hector Casimiro; Jalalvand, Ali R.; Exploiting second-order advantage from mathematically modeled voltammetric data for simultaneous determination of multiple antiparkinson agents in the presence of uncalibrated interference; Elsevier Science; Journal Of The Taiwan Institute Of Chemical Engineers; 88; 7-2018; 49-61 1876-1070 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://linkinghub.elsevier.com/retrieve/pii/S1876107018302189 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jtice.2018.04.007 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier Science |
publisher.none.fl_str_mv |
Elsevier Science |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613223640203264 |
score |
13.070432 |