Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic

Autores
Perez Recalde, Maria Mercedes; Noseda, Miguel D.; Pujol, Carlos Alberto; Carlucci, Maria Josefina; Matulewicz, Maria Cristina
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nemalion helminthoides, collected in the Argentine South Atlantic coast, was extracted with hot water and the crude product fractionated using cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration and seven fractions were separated and analyzed. Structural analysis of the main fractions, those soluble in 3.0 and 4.0 M NaCl (yields 21.0% and 13.8%, respectively) and those insoluble in 4.0 M NaCl (yield 20.0%), indicated that this seaweed biosynthesizes (1 → 3)-linked α-d-mannans that are sulfated at positions 4 and 6. Three mannan fractions comprising considerable amounts of xylose were also isolated in very low total yield (2.0%). The fractions that were soluble in 3.0 and 4.0 M NaCl showed low antiherpetic activity whereas this activity was considerable for the fraction solubilized in 2.0 M NaCl (yield 0.5%) which contained single stubs of β-d-xylose. A xylan, soluble in cetrimide solution, containing (1 → 3, 1 → 4)-linked β-d-xylose residues, was also isolated in minor amount. © 2009 Elsevier Ltd. All rights reserved.
Fil: Perez Recalde, Maria Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Noseda, Miguel D.. Universidade Federal do Paraná; Brasil
Fil: Pujol, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Carlucci, Maria Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Matulewicz, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Materia
Antiherpetic Activity
Nemaliales
Nemalion Helminthoides
Red Seaweed
Sulfated (1 ↠ 3)-Linked Α-D-Mannans
Sulfated Mannans
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/67863
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/67863
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Sulfated mannans from the red seaweed Nemalion helminthoides of the South AtlanticPerez Recalde, Maria MercedesNoseda, Miguel D.Pujol, Carlos AlbertoCarlucci, Maria JosefinaMatulewicz, Maria CristinaAntiherpetic ActivityNemalialesNemalion HelminthoidesRed SeaweedSulfated (1 ↠ 3)-Linked Α-D-MannansSulfated Mannanshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Nemalion helminthoides, collected in the Argentine South Atlantic coast, was extracted with hot water and the crude product fractionated using cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration and seven fractions were separated and analyzed. Structural analysis of the main fractions, those soluble in 3.0 and 4.0 M NaCl (yields 21.0% and 13.8%, respectively) and those insoluble in 4.0 M NaCl (yield 20.0%), indicated that this seaweed biosynthesizes (1 → 3)-linked α-d-mannans that are sulfated at positions 4 and 6. Three mannan fractions comprising considerable amounts of xylose were also isolated in very low total yield (2.0%). The fractions that were soluble in 3.0 and 4.0 M NaCl showed low antiherpetic activity whereas this activity was considerable for the fraction solubilized in 2.0 M NaCl (yield 0.5%) which contained single stubs of β-d-xylose. A xylan, soluble in cetrimide solution, containing (1 → 3, 1 → 4)-linked β-d-xylose residues, was also isolated in minor amount. © 2009 Elsevier Ltd. All rights reserved.Fil: Perez Recalde, Maria Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Noseda, Miguel D.. Universidade Federal do Paraná; BrasilFil: Pujol, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; ArgentinaFil: Carlucci, Maria Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; ArgentinaFil: Matulewicz, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaPergamon-Elsevier Science Ltd2009-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/67863Perez Recalde, Maria Mercedes; Noseda, Miguel D.; Pujol, Carlos Alberto; Carlucci, Maria Josefina; Matulewicz, Maria Cristina; Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic; Pergamon-Elsevier Science Ltd; Phytochemistry; 70; 8; 5-2009; 1062-10680031-9422CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.phytochem.2009.05.001info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031942209001782info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:00:06Zoai:ri.conicet.gov.ar:11336/67863instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:00:06.911CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
title Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
spellingShingle Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
Perez Recalde, Maria Mercedes
Antiherpetic Activity
Nemaliales
Nemalion Helminthoides
Red Seaweed
Sulfated (1 ↠ 3)-Linked Α-D-Mannans
Sulfated Mannans
title_short Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
title_full Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
title_fullStr Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
title_full_unstemmed Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
title_sort Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic
dc.creator.none.fl_str_mv Perez Recalde, Maria Mercedes
Noseda, Miguel D.
Pujol, Carlos Alberto
Carlucci, Maria Josefina
Matulewicz, Maria Cristina
author Perez Recalde, Maria Mercedes
author_facet Perez Recalde, Maria Mercedes
Noseda, Miguel D.
Pujol, Carlos Alberto
Carlucci, Maria Josefina
Matulewicz, Maria Cristina
author_role author
author2 Noseda, Miguel D.
Pujol, Carlos Alberto
Carlucci, Maria Josefina
Matulewicz, Maria Cristina
author2_role author
author
author
author
dc.subject.none.fl_str_mv Antiherpetic Activity
Nemaliales
Nemalion Helminthoides
Red Seaweed
Sulfated (1 ↠ 3)-Linked Α-D-Mannans
Sulfated Mannans
topic Antiherpetic Activity
Nemaliales
Nemalion Helminthoides
Red Seaweed
Sulfated (1 ↠ 3)-Linked Α-D-Mannans
Sulfated Mannans
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Nemalion helminthoides, collected in the Argentine South Atlantic coast, was extracted with hot water and the crude product fractionated using cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration and seven fractions were separated and analyzed. Structural analysis of the main fractions, those soluble in 3.0 and 4.0 M NaCl (yields 21.0% and 13.8%, respectively) and those insoluble in 4.0 M NaCl (yield 20.0%), indicated that this seaweed biosynthesizes (1 → 3)-linked α-d-mannans that are sulfated at positions 4 and 6. Three mannan fractions comprising considerable amounts of xylose were also isolated in very low total yield (2.0%). The fractions that were soluble in 3.0 and 4.0 M NaCl showed low antiherpetic activity whereas this activity was considerable for the fraction solubilized in 2.0 M NaCl (yield 0.5%) which contained single stubs of β-d-xylose. A xylan, soluble in cetrimide solution, containing (1 → 3, 1 → 4)-linked β-d-xylose residues, was also isolated in minor amount. © 2009 Elsevier Ltd. All rights reserved.
Fil: Perez Recalde, Maria Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Noseda, Miguel D.. Universidade Federal do Paraná; Brasil
Fil: Pujol, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Carlucci, Maria Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Matulewicz, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
description Nemalion helminthoides, collected in the Argentine South Atlantic coast, was extracted with hot water and the crude product fractionated using cetrimide. The complexed material was subjected to fractional solubilization in solutions of increasing sodium chloride concentration and seven fractions were separated and analyzed. Structural analysis of the main fractions, those soluble in 3.0 and 4.0 M NaCl (yields 21.0% and 13.8%, respectively) and those insoluble in 4.0 M NaCl (yield 20.0%), indicated that this seaweed biosynthesizes (1 → 3)-linked α-d-mannans that are sulfated at positions 4 and 6. Three mannan fractions comprising considerable amounts of xylose were also isolated in very low total yield (2.0%). The fractions that were soluble in 3.0 and 4.0 M NaCl showed low antiherpetic activity whereas this activity was considerable for the fraction solubilized in 2.0 M NaCl (yield 0.5%) which contained single stubs of β-d-xylose. A xylan, soluble in cetrimide solution, containing (1 → 3, 1 → 4)-linked β-d-xylose residues, was also isolated in minor amount. © 2009 Elsevier Ltd. All rights reserved.
publishDate 2009
dc.date.none.fl_str_mv 2009-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/67863
Perez Recalde, Maria Mercedes; Noseda, Miguel D.; Pujol, Carlos Alberto; Carlucci, Maria Josefina; Matulewicz, Maria Cristina; Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic; Pergamon-Elsevier Science Ltd; Phytochemistry; 70; 8; 5-2009; 1062-1068
0031-9422
CONICET Digital
CONICET
url http://hdl.handle.net/11336/67863
identifier_str_mv Perez Recalde, Maria Mercedes; Noseda, Miguel D.; Pujol, Carlos Alberto; Carlucci, Maria Josefina; Matulewicz, Maria Cristina; Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic; Pergamon-Elsevier Science Ltd; Phytochemistry; 70; 8; 5-2009; 1062-1068
0031-9422
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.phytochem.2009.05.001
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031942209001782
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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