Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the A...

Autores: Trotta, Milagros; Agustini, Camila; Rohr, Cristian Oscar; Ame, Ricardo Martín; Giordano, Laureano Jose; Balderramo, Domingo; Romagnoli, Pablo Alberto; Vazquez, Martin
Año de publicación: 2025
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Carbohydrate-active enzyme (CAZyme) activity in the gut microbiome has significant implications for health, including the release of nutrients otherwise inaccessible to the host and the enhancement of digestive efficiency. The primary end products of indigestible carbohydrate fermentation are short-chain fatty acids (SCFAs). We hypothesized that increased dietary fiber consumption could lead to greater SCFA production in the human gut. To investigate this, we examined the relationship between complex carbohydrate intake, CAZyme activity in the human gut microbiome, and SCFA production at the whole metagenomic level across three cohorts: a healthy reference-controlled cohort, an average cohort of individuals living in industrialized cities, and a cohort of patients with inflammatory bowel disease (IBD). Metagenomic sequencing and bioinformatic analyses were utilized to assess the diversity, abundance, and functionality of CAZymes, as well as the metabolic capacity for SCFA production. The average cohort exhibited higher alpha diversity of CAZyme families compared to the reference-controlled cohort, although subfamily composition was similar between both. A moderate negative correlation was identified between CAZyme abundance and SCFA production, indicating that a higher number of these enzymes does not directly translate to increased SCFA synthesis. In IBD patients, a decrease in the diversity and composition of CAZyme subfamilies was observed, suggesting a disruption in enzymatic functions associated with the disease. However, the overall functionality of CAZymes remained relatively stable across different health conditions, highlighting the resilience of the gut microbiome for these functions. These findings deepen our understanding of the gut microbiome’s role in health and disease, emphasizing that despite variations in microbial diversity, key enzymatic functions persist. The study underscores the complexity of the non-linear relationship between complex carbohydrate metabolism and SCFA production, laying the groundwork for future research on microbiome-targeted therapeutic/dietary profile interventions in both non-disease and chronic diseases conditions.
Fil: Trotta, Milagros. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);
Fil: Agustini, Camila. Heritas S.a (heritas S.a);
Fil: Rohr, Cristian Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);
Fil: Ame, Ricardo Martín. Hospital Privado Universitario de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina
Fil: Giordano, Laureano Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina
Fil: Balderramo, Domingo. Hospital Privado Universitario de Córdoba; Argentina
Fil: Romagnoli, Pablo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa | Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina
Fil: Vazquez, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);
Materia: GUT MICROBIOME
CAZYMES
SCFAS
IBD
MICROBIAL DIVERSITY
ENZYMATIC FUNCTIONALITY
MICROBIOME RESILIENCE
Nivel de accesibilidad: acceso abierto
Condiciones de uso: https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
Institución: Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador: oai:ri.conicet.gov.ar:11336/274101

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repository_id_str	3498
network_name_str	CONICET Digital (CONICET)
spelling	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine populationTrotta, MilagrosAgustini, CamilaRohr, Cristian OscarAme, Ricardo MartínGiordano, Laureano JoseBalderramo, DomingoRomagnoli, Pablo AlbertoVazquez, MartinGUT MICROBIOMECAZYMESSCFASIBDMICROBIAL DIVERSITYENZYMATIC FUNCTIONALITYMICROBIOME RESILIENCEhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Carbohydrate-active enzyme (CAZyme) activity in the gut microbiome has significant implications for health, including the release of nutrients otherwise inaccessible to the host and the enhancement of digestive efficiency. The primary end products of indigestible carbohydrate fermentation are short-chain fatty acids (SCFAs). We hypothesized that increased dietary fiber consumption could lead to greater SCFA production in the human gut. To investigate this, we examined the relationship between complex carbohydrate intake, CAZyme activity in the human gut microbiome, and SCFA production at the whole metagenomic level across three cohorts: a healthy reference-controlled cohort, an average cohort of individuals living in industrialized cities, and a cohort of patients with inflammatory bowel disease (IBD). Metagenomic sequencing and bioinformatic analyses were utilized to assess the diversity, abundance, and functionality of CAZymes, as well as the metabolic capacity for SCFA production. The average cohort exhibited higher alpha diversity of CAZyme families compared to the reference-controlled cohort, although subfamily composition was similar between both. A moderate negative correlation was identified between CAZyme abundance and SCFA production, indicating that a higher number of these enzymes does not directly translate to increased SCFA synthesis. In IBD patients, a decrease in the diversity and composition of CAZyme subfamilies was observed, suggesting a disruption in enzymatic functions associated with the disease. However, the overall functionality of CAZymes remained relatively stable across different health conditions, highlighting the resilience of the gut microbiome for these functions. These findings deepen our understanding of the gut microbiome’s role in health and disease, emphasizing that despite variations in microbial diversity, key enzymatic functions persist. The study underscores the complexity of the non-linear relationship between complex carbohydrate metabolism and SCFA production, laying the groundwork for future research on microbiome-targeted therapeutic/dietary profile interventions in both non-disease and chronic diseases conditions.Fil: Trotta, Milagros. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);Fil: Agustini, Camila. Heritas S.a (heritas S.a);Fil: Rohr, Cristian Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);Fil: Ame, Ricardo Martín. Hospital Privado Universitario de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; ArgentinaFil: Giordano, Laureano Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; ArgentinaFil: Balderramo, Domingo. Hospital Privado Universitario de Córdoba; ArgentinaFil: Romagnoli, Pablo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; ArgentinaFil: Vazquez, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);Cold Spring Harbor Laboratory Press2025-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/274101Trotta, Milagros; Agustini, Camila; Rohr, Cristian Oscar; Ame, Ricardo Martín; Giordano, Laureano Jose; et al.; Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population; Cold Spring Harbor Laboratory Press; bioXriv; 5-2025; 1-192692-8205CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.biorxiv.org/content/10.1101/2025.05.15.654276v1info:eu-repo/semantics/altIdentifier/doi/10.1101/2025.05.15.654276info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T09:43:06Zoai:ri.conicet.gov.ar:11336/274101instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 09:43:06.567CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
title	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
spellingShingle	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population Trotta, Milagros GUT MICROBIOME CAZYMES SCFAS IBD MICROBIAL DIVERSITY ENZYMATIC FUNCTIONALITY MICROBIOME RESILIENCE
title_short	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
title_full	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
title_fullStr	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
title_full_unstemmed	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
title_sort	Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population
dc.creator.none.fl_str_mv	Trotta, Milagros Agustini, Camila Rohr, Cristian Oscar Ame, Ricardo Martín Giordano, Laureano Jose Balderramo, Domingo Romagnoli, Pablo Alberto Vazquez, Martin
author	Trotta, Milagros
author_facet	Trotta, Milagros Agustini, Camila Rohr, Cristian Oscar Ame, Ricardo Martín Giordano, Laureano Jose Balderramo, Domingo Romagnoli, Pablo Alberto Vazquez, Martin
author_role	author
author2	Agustini, Camila Rohr, Cristian Oscar Ame, Ricardo Martín Giordano, Laureano Jose Balderramo, Domingo Romagnoli, Pablo Alberto Vazquez, Martin
author2_role	author author author author author author author
dc.subject.none.fl_str_mv	GUT MICROBIOME CAZYMES SCFAS IBD MICROBIAL DIVERSITY ENZYMATIC FUNCTIONALITY MICROBIOME RESILIENCE
topic	GUT MICROBIOME CAZYMES SCFAS IBD MICROBIAL DIVERSITY ENZYMATIC FUNCTIONALITY MICROBIOME RESILIENCE
purl_subject.fl_str_mv	https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv	Carbohydrate-active enzyme (CAZyme) activity in the gut microbiome has significant implications for health, including the release of nutrients otherwise inaccessible to the host and the enhancement of digestive efficiency. The primary end products of indigestible carbohydrate fermentation are short-chain fatty acids (SCFAs). We hypothesized that increased dietary fiber consumption could lead to greater SCFA production in the human gut. To investigate this, we examined the relationship between complex carbohydrate intake, CAZyme activity in the human gut microbiome, and SCFA production at the whole metagenomic level across three cohorts: a healthy reference-controlled cohort, an average cohort of individuals living in industrialized cities, and a cohort of patients with inflammatory bowel disease (IBD). Metagenomic sequencing and bioinformatic analyses were utilized to assess the diversity, abundance, and functionality of CAZymes, as well as the metabolic capacity for SCFA production. The average cohort exhibited higher alpha diversity of CAZyme families compared to the reference-controlled cohort, although subfamily composition was similar between both. A moderate negative correlation was identified between CAZyme abundance and SCFA production, indicating that a higher number of these enzymes does not directly translate to increased SCFA synthesis. In IBD patients, a decrease in the diversity and composition of CAZyme subfamilies was observed, suggesting a disruption in enzymatic functions associated with the disease. However, the overall functionality of CAZymes remained relatively stable across different health conditions, highlighting the resilience of the gut microbiome for these functions. These findings deepen our understanding of the gut microbiome’s role in health and disease, emphasizing that despite variations in microbial diversity, key enzymatic functions persist. The study underscores the complexity of the non-linear relationship between complex carbohydrate metabolism and SCFA production, laying the groundwork for future research on microbiome-targeted therapeutic/dietary profile interventions in both non-disease and chronic diseases conditions. Fil: Trotta, Milagros. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a); Fil: Agustini, Camila. Heritas S.a (heritas S.a); Fil: Rohr, Cristian Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a); Fil: Ame, Ricardo Martín. Hospital Privado Universitario de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina Fil: Giordano, Laureano Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina Fil: Balderramo, Domingo. Hospital Privado Universitario de Córdoba; Argentina Fil: Romagnoli, Pablo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa \| Instituto de Investigación Médica Mercedes y Martín Ferreyra. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Grupo Vinculado Centro de Investigación en Medicina Traslacional Severo R. Amuchástegui - Cimetsa; Argentina Fil: Vazquez, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Heritas S.a (heritas S.a);
description	Carbohydrate-active enzyme (CAZyme) activity in the gut microbiome has significant implications for health, including the release of nutrients otherwise inaccessible to the host and the enhancement of digestive efficiency. The primary end products of indigestible carbohydrate fermentation are short-chain fatty acids (SCFAs). We hypothesized that increased dietary fiber consumption could lead to greater SCFA production in the human gut. To investigate this, we examined the relationship between complex carbohydrate intake, CAZyme activity in the human gut microbiome, and SCFA production at the whole metagenomic level across three cohorts: a healthy reference-controlled cohort, an average cohort of individuals living in industrialized cities, and a cohort of patients with inflammatory bowel disease (IBD). Metagenomic sequencing and bioinformatic analyses were utilized to assess the diversity, abundance, and functionality of CAZymes, as well as the metabolic capacity for SCFA production. The average cohort exhibited higher alpha diversity of CAZyme families compared to the reference-controlled cohort, although subfamily composition was similar between both. A moderate negative correlation was identified between CAZyme abundance and SCFA production, indicating that a higher number of these enzymes does not directly translate to increased SCFA synthesis. In IBD patients, a decrease in the diversity and composition of CAZyme subfamilies was observed, suggesting a disruption in enzymatic functions associated with the disease. However, the overall functionality of CAZymes remained relatively stable across different health conditions, highlighting the resilience of the gut microbiome for these functions. These findings deepen our understanding of the gut microbiome’s role in health and disease, emphasizing that despite variations in microbial diversity, key enzymatic functions persist. The study underscores the complexity of the non-linear relationship between complex carbohydrate metabolism and SCFA production, laying the groundwork for future research on microbiome-targeted therapeutic/dietary profile interventions in both non-disease and chronic diseases conditions.
publishDate	2025
dc.date.none.fl_str_mv	2025-05
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/11336/274101 Trotta, Milagros; Agustini, Camila; Rohr, Cristian Oscar; Ame, Ricardo Martín; Giordano, Laureano Jose; et al.; Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population; Cold Spring Harbor Laboratory Press; bioXriv; 5-2025; 1-19 2692-8205 CONICET Digital CONICET
url	http://hdl.handle.net/11336/274101
identifier_str_mv	Trotta, Milagros; Agustini, Camila; Rohr, Cristian Oscar; Ame, Ricardo Martín; Giordano, Laureano Jose; et al.; Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the Argentine population; Cold Spring Harbor Laboratory Press; bioXriv; 5-2025; 1-19 2692-8205 CONICET Digital CONICET
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/url/https://www.biorxiv.org/content/10.1101/2025.05.15.654276v1 info:eu-repo/semantics/altIdentifier/doi/10.1101/2025.05.15.654276
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv	openAccess
rights_invalid_str_mv	https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv	application/pdf application/pdf
dc.publisher.none.fl_str_mv	Cold Spring Harbor Laboratory Press
publisher.none.fl_str_mv	Cold Spring Harbor Laboratory Press
dc.source.none.fl_str_mv	reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str	CONICET Digital (CONICET)
collection	CONICET Digital (CONICET)
instname_str	Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv	CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv	dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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Exploring the interplay of complex carbohydrate intake, the microbiome CAZymes pool and short-chain fatty acid production in the human gut: Insights from different cohorts in the A...

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