The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change

Autores
Cabrera, Joaquin; González, Paula Mariela; Puntarulo, Susana Ángela
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Harmful algal blooms (HAB) threaten aquatic and marine ecosystems and wildlife through the creation of hypoxic conditions, and through the toxins they produce. Climate change is creating conditions that increase the impact of HAB on the aquatic ecosystems, rising the frequency of these events. Domoic acid (DA) is a marine phycotoxin produced during HAB of the diatoms Pseudonitzchia sp. It was described that DA causes production of reactive oxygen species (ROS), neurological dysfunction, DNA damage, lipid peroxidation, energy depletion, mitochondrial damage and cell death in animals and humans. However, the information about the effect of this phycotoxin on the non-toxin producing phytoplankton community is scarce or null in relation to oxidative stress measurements. The hypothesis of this opinion article is that DA produced by HAB, might favor the generation of reactive species, that through diffusion to the extracellular environment modifies the oxidative metabolism of non-toxin-producing marine phytoplankton. This feature opens the possibility that not only the phytoplankton community, but also the rest of the food web might be deeply affected if, due to global warming, HAB magnitude and frequency continue increasing.
Fil: Cabrera, Joaquin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: González, Paula Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Materia
CLIMATE CHANGE
DOMOIC ACID
HARMFUL MARINE TOXINS
OXIDATIVE STRESS
PHOTOSYNTHETIC ORGANISMS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/139221
Acceder
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network_name_str CONICET Digital (CONICET)
spelling The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate ChangeCabrera, JoaquinGonzález, Paula MarielaPuntarulo, Susana ÁngelaCLIMATE CHANGEDOMOIC ACIDHARMFUL MARINE TOXINSOXIDATIVE STRESSPHOTOSYNTHETIC ORGANISMShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Harmful algal blooms (HAB) threaten aquatic and marine ecosystems and wildlife through the creation of hypoxic conditions, and through the toxins they produce. Climate change is creating conditions that increase the impact of HAB on the aquatic ecosystems, rising the frequency of these events. Domoic acid (DA) is a marine phycotoxin produced during HAB of the diatoms Pseudonitzchia sp. It was described that DA causes production of reactive oxygen species (ROS), neurological dysfunction, DNA damage, lipid peroxidation, energy depletion, mitochondrial damage and cell death in animals and humans. However, the information about the effect of this phycotoxin on the non-toxin producing phytoplankton community is scarce or null in relation to oxidative stress measurements. The hypothesis of this opinion article is that DA produced by HAB, might favor the generation of reactive species, that through diffusion to the extracellular environment modifies the oxidative metabolism of non-toxin-producing marine phytoplankton. This feature opens the possibility that not only the phytoplankton community, but also the rest of the food web might be deeply affected if, due to global warming, HAB magnitude and frequency continue increasing.Fil: Cabrera, Joaquin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; ArgentinaFil: González, Paula Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; ArgentinaFil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; ArgentinaFrontiers Media S.A.2020-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/139221Cabrera, Joaquin; González, Paula Mariela; Puntarulo, Susana Ángela; The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change; Frontiers Media S.A.; Frontiers in Plant Science; 11; 10-2020; 1-71664-462X1664-462XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fpls.2020.576971/fullinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fpls.2020.576971info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:19:59Zoai:ri.conicet.gov.ar:11336/139221instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:19:59.805CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
title The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
spellingShingle The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
Cabrera, Joaquin
CLIMATE CHANGE
DOMOIC ACID
HARMFUL MARINE TOXINS
OXIDATIVE STRESS
PHOTOSYNTHETIC ORGANISMS
title_short The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
title_full The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
title_fullStr The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
title_full_unstemmed The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
title_sort The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change
dc.creator.none.fl_str_mv Cabrera, Joaquin
González, Paula Mariela
Puntarulo, Susana Ángela
author Cabrera, Joaquin
author_facet Cabrera, Joaquin
González, Paula Mariela
Puntarulo, Susana Ángela
author_role author
author2 González, Paula Mariela
Puntarulo, Susana Ángela
author2_role author
author
dc.subject.none.fl_str_mv CLIMATE CHANGE
DOMOIC ACID
HARMFUL MARINE TOXINS
OXIDATIVE STRESS
PHOTOSYNTHETIC ORGANISMS
topic CLIMATE CHANGE
DOMOIC ACID
HARMFUL MARINE TOXINS
OXIDATIVE STRESS
PHOTOSYNTHETIC ORGANISMS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Harmful algal blooms (HAB) threaten aquatic and marine ecosystems and wildlife through the creation of hypoxic conditions, and through the toxins they produce. Climate change is creating conditions that increase the impact of HAB on the aquatic ecosystems, rising the frequency of these events. Domoic acid (DA) is a marine phycotoxin produced during HAB of the diatoms Pseudonitzchia sp. It was described that DA causes production of reactive oxygen species (ROS), neurological dysfunction, DNA damage, lipid peroxidation, energy depletion, mitochondrial damage and cell death in animals and humans. However, the information about the effect of this phycotoxin on the non-toxin producing phytoplankton community is scarce or null in relation to oxidative stress measurements. The hypothesis of this opinion article is that DA produced by HAB, might favor the generation of reactive species, that through diffusion to the extracellular environment modifies the oxidative metabolism of non-toxin-producing marine phytoplankton. This feature opens the possibility that not only the phytoplankton community, but also the rest of the food web might be deeply affected if, due to global warming, HAB magnitude and frequency continue increasing.
Fil: Cabrera, Joaquin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: González, Paula Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
description Harmful algal blooms (HAB) threaten aquatic and marine ecosystems and wildlife through the creation of hypoxic conditions, and through the toxins they produce. Climate change is creating conditions that increase the impact of HAB on the aquatic ecosystems, rising the frequency of these events. Domoic acid (DA) is a marine phycotoxin produced during HAB of the diatoms Pseudonitzchia sp. It was described that DA causes production of reactive oxygen species (ROS), neurological dysfunction, DNA damage, lipid peroxidation, energy depletion, mitochondrial damage and cell death in animals and humans. However, the information about the effect of this phycotoxin on the non-toxin producing phytoplankton community is scarce or null in relation to oxidative stress measurements. The hypothesis of this opinion article is that DA produced by HAB, might favor the generation of reactive species, that through diffusion to the extracellular environment modifies the oxidative metabolism of non-toxin-producing marine phytoplankton. This feature opens the possibility that not only the phytoplankton community, but also the rest of the food web might be deeply affected if, due to global warming, HAB magnitude and frequency continue increasing.
publishDate 2020
dc.date.none.fl_str_mv 2020-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/139221
Cabrera, Joaquin; González, Paula Mariela; Puntarulo, Susana Ángela; The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change; Frontiers Media S.A.; Frontiers in Plant Science; 11; 10-2020; 1-7
1664-462X
1664-462X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/139221
identifier_str_mv Cabrera, Joaquin; González, Paula Mariela; Puntarulo, Susana Ángela; The Phycotoxin Domoic Acid as a Potential Factor for Oxidative Alterations Enhanced by Climate Change; Frontiers Media S.A.; Frontiers in Plant Science; 11; 10-2020; 1-7
1664-462X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fpls.2020.576971/full
info:eu-repo/semantics/altIdentifier/doi/10.3389/fpls.2020.576971
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media S.A.
publisher.none.fl_str_mv Frontiers Media S.A.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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