Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection

Autores
Isa, Maria Beatriz; Pavan, Jorge Victorio; Sicilia Don, Paola Ermelinda; Grutadauria, S.; Martinez, Laura Cecilia; Giordano, Miguel Oscar; Masachessi, Gisela; Barril, Patricia Angelica; Nates, Silvia Viviana
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Little is known about long-lasting measles protective immunity when exposure to wild-type or vaccine measles virus precedes HIV infection. The results obtained suggest that measles immunity wanes and the lowest measles geometric mean titres (GMT) were significantly associated with measles vaccine-induced immunity in individuals that later developed HIV infection (86% prevalence, GMT 164 mIU/ml) compared to naturally induced immunity in HIV-infected adults (100% prevalence, GMT 340 mIU/ml, P= 0·0082) or non-HIV infected adults (100%, GMT 724 mIU/ml, P= 0·0001), and vaccine-induced immunity in non-HIV-infected adults (100%, GMT 347 mIU/ml, P= 0·017). The study was conducted in an area without wild-type virus circulation since 2000. The absence of virus circulating may alter the paradigm of lifelong immunity to measles virus after vaccination. As the proportion of HIV-infected individuals possessing only vaccine-induced immunity continues to grow, checking the status of measles immunity in this group is strongly recommended
Fil: Isa, Maria Beatriz. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Universidad Catolica de Córdoba. Facultad de Medicina. Clinica Universitaria Reina Fabiola; Argentina
Fil: Pavan, Jorge Victorio. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sicilia Don, Paola Ermelinda. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Grutadauria, S.. Sanatorio Allende; Argentina
Fil: Martinez, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Giordano, Miguel Oscar. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Masachessi, Gisela. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Barril, Patricia Angelica. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Nates, Silvia Viviana. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Hiv
Infected Adults
Measles
Measles Immunity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/29270
Acceder
id CONICETDig_6fd57e93bda19854c3230b77f123bb66
oai_identifier_str oai:ri.conicet.gov.ar:11336/29270
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infectionIsa, Maria BeatrizPavan, Jorge VictorioSicilia Don, Paola ErmelindaGrutadauria, S.Martinez, Laura CeciliaGiordano, Miguel OscarMasachessi, GiselaBarril, Patricia AngelicaNates, Silvia VivianaHivInfected AdultsMeaslesMeasles Immunityhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Little is known about long-lasting measles protective immunity when exposure to wild-type or vaccine measles virus precedes HIV infection. The results obtained suggest that measles immunity wanes and the lowest measles geometric mean titres (GMT) were significantly associated with measles vaccine-induced immunity in individuals that later developed HIV infection (86% prevalence, GMT 164 mIU/ml) compared to naturally induced immunity in HIV-infected adults (100% prevalence, GMT 340 mIU/ml, P= 0·0082) or non-HIV infected adults (100%, GMT 724 mIU/ml, P= 0·0001), and vaccine-induced immunity in non-HIV-infected adults (100%, GMT 347 mIU/ml, P= 0·017). The study was conducted in an area without wild-type virus circulation since 2000. The absence of virus circulating may alter the paradigm of lifelong immunity to measles virus after vaccination. As the proportion of HIV-infected individuals possessing only vaccine-induced immunity continues to grow, checking the status of measles immunity in this group is strongly recommendedFil: Isa, Maria Beatriz. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Universidad Catolica de Córdoba. Facultad de Medicina. Clinica Universitaria Reina Fabiola; ArgentinaFil: Pavan, Jorge Victorio. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sicilia Don, Paola Ermelinda. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; ArgentinaFil: Grutadauria, S.. Sanatorio Allende; ArgentinaFil: Martinez, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; ArgentinaFil: Giordano, Miguel Oscar. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Masachessi, Gisela. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Barril, Patricia Angelica. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Nates, Silvia Viviana. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaCambridge University Press2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/29270Isa, Maria Beatriz; Pavan, Jorge Victorio; Sicilia Don, Paola Ermelinda; Grutadauria, S.; Martinez, Laura Cecilia; et al.; Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection; Cambridge University Press; Epidemiology and Infection; 142; 8; 10-2013; 1708-17120950-2688CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1017/S0950268813002628info:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/journals/epidemiology-and-infection/article/persistence-of-measles-neutralizing-antibody-related-to-vaccine-and-natural-infection-acquired-before-hiv-infection/C4752DD8225B49AC7425E82C5471354Binfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:27:23Zoai:ri.conicet.gov.ar:11336/29270instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:27:24.102CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
title Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
spellingShingle Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
Isa, Maria Beatriz
Hiv
Infected Adults
Measles
Measles Immunity
title_short Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
title_full Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
title_fullStr Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
title_full_unstemmed Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
title_sort Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection
dc.creator.none.fl_str_mv Isa, Maria Beatriz
Pavan, Jorge Victorio
Sicilia Don, Paola Ermelinda
Grutadauria, S.
Martinez, Laura Cecilia
Giordano, Miguel Oscar
Masachessi, Gisela
Barril, Patricia Angelica
Nates, Silvia Viviana
author Isa, Maria Beatriz
author_facet Isa, Maria Beatriz
Pavan, Jorge Victorio
Sicilia Don, Paola Ermelinda
Grutadauria, S.
Martinez, Laura Cecilia
Giordano, Miguel Oscar
Masachessi, Gisela
Barril, Patricia Angelica
Nates, Silvia Viviana
author_role author
author2 Pavan, Jorge Victorio
Sicilia Don, Paola Ermelinda
Grutadauria, S.
Martinez, Laura Cecilia
Giordano, Miguel Oscar
Masachessi, Gisela
Barril, Patricia Angelica
Nates, Silvia Viviana
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hiv
Infected Adults
Measles
Measles Immunity
topic Hiv
Infected Adults
Measles
Measles Immunity
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Little is known about long-lasting measles protective immunity when exposure to wild-type or vaccine measles virus precedes HIV infection. The results obtained suggest that measles immunity wanes and the lowest measles geometric mean titres (GMT) were significantly associated with measles vaccine-induced immunity in individuals that later developed HIV infection (86% prevalence, GMT 164 mIU/ml) compared to naturally induced immunity in HIV-infected adults (100% prevalence, GMT 340 mIU/ml, P= 0·0082) or non-HIV infected adults (100%, GMT 724 mIU/ml, P= 0·0001), and vaccine-induced immunity in non-HIV-infected adults (100%, GMT 347 mIU/ml, P= 0·017). The study was conducted in an area without wild-type virus circulation since 2000. The absence of virus circulating may alter the paradigm of lifelong immunity to measles virus after vaccination. As the proportion of HIV-infected individuals possessing only vaccine-induced immunity continues to grow, checking the status of measles immunity in this group is strongly recommended
Fil: Isa, Maria Beatriz. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Universidad Catolica de Córdoba. Facultad de Medicina. Clinica Universitaria Reina Fabiola; Argentina
Fil: Pavan, Jorge Victorio. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sicilia Don, Paola Ermelinda. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Grutadauria, S.. Sanatorio Allende; Argentina
Fil: Martinez, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Giordano, Miguel Oscar. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Masachessi, Gisela. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Barril, Patricia Angelica. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Nates, Silvia Viviana. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Little is known about long-lasting measles protective immunity when exposure to wild-type or vaccine measles virus precedes HIV infection. The results obtained suggest that measles immunity wanes and the lowest measles geometric mean titres (GMT) were significantly associated with measles vaccine-induced immunity in individuals that later developed HIV infection (86% prevalence, GMT 164 mIU/ml) compared to naturally induced immunity in HIV-infected adults (100% prevalence, GMT 340 mIU/ml, P= 0·0082) or non-HIV infected adults (100%, GMT 724 mIU/ml, P= 0·0001), and vaccine-induced immunity in non-HIV-infected adults (100%, GMT 347 mIU/ml, P= 0·017). The study was conducted in an area without wild-type virus circulation since 2000. The absence of virus circulating may alter the paradigm of lifelong immunity to measles virus after vaccination. As the proportion of HIV-infected individuals possessing only vaccine-induced immunity continues to grow, checking the status of measles immunity in this group is strongly recommended
publishDate 2013
dc.date.none.fl_str_mv 2013-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/29270
Isa, Maria Beatriz; Pavan, Jorge Victorio; Sicilia Don, Paola Ermelinda; Grutadauria, S.; Martinez, Laura Cecilia; et al.; Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection; Cambridge University Press; Epidemiology and Infection; 142; 8; 10-2013; 1708-1712
0950-2688
CONICET Digital
CONICET
url http://hdl.handle.net/11336/29270
identifier_str_mv Isa, Maria Beatriz; Pavan, Jorge Victorio; Sicilia Don, Paola Ermelinda; Grutadauria, S.; Martinez, Laura Cecilia; et al.; Persistence of measles neutralizing antibody related to vaccine and natural infection adquired before HIV infection; Cambridge University Press; Epidemiology and Infection; 142; 8; 10-2013; 1708-1712
0950-2688
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1017/S0950268813002628
info:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/journals/epidemiology-and-infection/article/persistence-of-measles-neutralizing-antibody-related-to-vaccine-and-natural-infection-acquired-before-hiv-infection/C4752DD8225B49AC7425E82C5471354B
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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