Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells

Autores
Grasso, Ernesto Javier
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of the main features of the umbrella cells. However, our workgroup has dedicated to the study of lipid membrane composition and its biological impact in the urothelium. We first studied the lipid membrane composition of rat urothelium modified my dietary treatments differentiated in their fatty acid composition. Changes of lipid composition were related to the asymmetric unit membrane organization and permeability. Finally, we observed that the lipid composition was critically related to the intracellular pathways of discoidal/fusiform endocytic vesicles and their content. The purpose of this communication is to summarize the importance of lipids in the membrane organization and permeability of the apical plasma membrane and endocytic vesicles of umbrella cells.
Fil: Grasso, Ernesto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina
Materia
Urothelium
Umbrella Cells
Plasma Membrane
Fatty Acids
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/32102
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/32102
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella CellsGrasso, Ernesto JavierUrotheliumUmbrella CellsPlasma MembraneFatty Acidshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of the main features of the umbrella cells. However, our workgroup has dedicated to the study of lipid membrane composition and its biological impact in the urothelium. We first studied the lipid membrane composition of rat urothelium modified my dietary treatments differentiated in their fatty acid composition. Changes of lipid composition were related to the asymmetric unit membrane organization and permeability. Finally, we observed that the lipid composition was critically related to the intracellular pathways of discoidal/fusiform endocytic vesicles and their content. The purpose of this communication is to summarize the importance of lipids in the membrane organization and permeability of the apical plasma membrane and endocytic vesicles of umbrella cells.Fil: Grasso, Ernesto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; ArgentinaAmerican Association for Science and Technology2014-08-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/32102Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells; American Association for Science and Technology; AASCIT communications; 1; 2; 12-8-2014; 44-472375-3803CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.aascit.org/communications/paperInfo?journalId=940&paperId=564info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:00:21Zoai:ri.conicet.gov.ar:11336/32102instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:00:21.638CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
title Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
spellingShingle Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
Grasso, Ernesto Javier
Urothelium
Umbrella Cells
Plasma Membrane
Fatty Acids
title_short Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
title_full Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
title_fullStr Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
title_full_unstemmed Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
title_sort Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells
dc.creator.none.fl_str_mv Grasso, Ernesto Javier
author Grasso, Ernesto Javier
author_facet Grasso, Ernesto Javier
author_role author
dc.subject.none.fl_str_mv Urothelium
Umbrella Cells
Plasma Membrane
Fatty Acids
topic Urothelium
Umbrella Cells
Plasma Membrane
Fatty Acids
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of the main features of the umbrella cells. However, our workgroup has dedicated to the study of lipid membrane composition and its biological impact in the urothelium. We first studied the lipid membrane composition of rat urothelium modified my dietary treatments differentiated in their fatty acid composition. Changes of lipid composition were related to the asymmetric unit membrane organization and permeability. Finally, we observed that the lipid composition was critically related to the intracellular pathways of discoidal/fusiform endocytic vesicles and their content. The purpose of this communication is to summarize the importance of lipids in the membrane organization and permeability of the apical plasma membrane and endocytic vesicles of umbrella cells.
Fil: Grasso, Ernesto Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina
description The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of the main features of the umbrella cells. However, our workgroup has dedicated to the study of lipid membrane composition and its biological impact in the urothelium. We first studied the lipid membrane composition of rat urothelium modified my dietary treatments differentiated in their fatty acid composition. Changes of lipid composition were related to the asymmetric unit membrane organization and permeability. Finally, we observed that the lipid composition was critically related to the intracellular pathways of discoidal/fusiform endocytic vesicles and their content. The purpose of this communication is to summarize the importance of lipids in the membrane organization and permeability of the apical plasma membrane and endocytic vesicles of umbrella cells.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/32102
Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells; American Association for Science and Technology; AASCIT communications; 1; 2; 12-8-2014; 44-47
2375-3803
CONICET Digital
CONICET
url http://hdl.handle.net/11336/32102
identifier_str_mv Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells; American Association for Science and Technology; AASCIT communications; 1; 2; 12-8-2014; 44-47
2375-3803
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.aascit.org/communications/paperInfo?journalId=940&paperId=564
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Association for Science and Technology
publisher.none.fl_str_mv American Association for Science and Technology
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842979875721314304
score 12.48226

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