Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)

Autores
Galeano, Maria G.; Ruiz, Ruben Daniel; Fiol de Cuneo, Marta; Ponzio, Marina Flavia
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Due to its complexity and the relative lack of scientific reports, fur-chewing may be considered as one of the most challenging behavioural problems common to captive chinchillas. The development of this behaviour in commercial farms and the increasing popularity of this species as a pet have increased the public demands for a treatment. The objective of this work was to evaluate the effectiveness of fluoxetine to control the development of chinchillas’ fur-chewing behaviour, using an oral dose of 10 mg/kg/day for a 90 days treatment period. For the measurement of the fur-chewing affected area and its variation during treatment as external sign of whether or not the behaviour was controlled, digital pictures were taken at 0, 45, 75 and 90 days of treatment and after drug withdrawal at 140 days. Results indicated that the greatest difference in percentages of body area affected by the behaviour in control vs. treated animals was observed after 75 days of treatment. However, this was not due to a decrease in the amount of body area affected by fur-chewing in treated animals, but conversely to an increase in the symptoms observed in control animals, that showed a ~10% increase in the fur-chewing affected body area than at the beginning of the experiments. Only ~46% of the fluoxetine treated animals showed a significant reduction in the body area affected by fur-chewing. In summary, the use of fluoxetine in fur-chewing chinchillas showed limited success, mostly reducing the progression of the behaviour.
Fil: Galeano, Maria G.. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Ruiz, Ruben Daniel. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Fiol de Cuneo, Marta. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Ponzio, Marina Flavia. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Materia
Abnormal Repetitive Behaviour
Ssri
Obsessive-Compulsive
Stress
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/11371
Acceder
id CONICETDig_6cbb656f184ff92ff72a5fbaace30ee0
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)Galeano, Maria G.Ruiz, Ruben DanielFiol de Cuneo, MartaPonzio, Marina FlaviaAbnormal Repetitive BehaviourSsriObsessive-CompulsiveStresshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Due to its complexity and the relative lack of scientific reports, fur-chewing may be considered as one of the most challenging behavioural problems common to captive chinchillas. The development of this behaviour in commercial farms and the increasing popularity of this species as a pet have increased the public demands for a treatment. The objective of this work was to evaluate the effectiveness of fluoxetine to control the development of chinchillas’ fur-chewing behaviour, using an oral dose of 10 mg/kg/day for a 90 days treatment period. For the measurement of the fur-chewing affected area and its variation during treatment as external sign of whether or not the behaviour was controlled, digital pictures were taken at 0, 45, 75 and 90 days of treatment and after drug withdrawal at 140 days. Results indicated that the greatest difference in percentages of body area affected by the behaviour in control vs. treated animals was observed after 75 days of treatment. However, this was not due to a decrease in the amount of body area affected by fur-chewing in treated animals, but conversely to an increase in the symptoms observed in control animals, that showed a ~10% increase in the fur-chewing affected body area than at the beginning of the experiments. Only ~46% of the fluoxetine treated animals showed a significant reduction in the body area affected by fur-chewing. In summary, the use of fluoxetine in fur-chewing chinchillas showed limited success, mostly reducing the progression of the behaviour.Fil: Galeano, Maria G.. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Ruiz, Ruben Daniel. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Fiol de Cuneo, Marta. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Ponzio, Marina Flavia. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaElsevier Science2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11371Galeano, Maria G.; Ruiz, Ruben Daniel; Fiol de Cuneo, Marta; Ponzio, Marina Flavia; Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera); Elsevier Science; Applied Animal Behaviour Science; 146; 1-4; 6-2013; 112-1170168-1591enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.applanim.2013.04.003info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0168159113000993info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:38:57Zoai:ri.conicet.gov.ar:11336/11371instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:38:57.701CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
title Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
spellingShingle Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
Galeano, Maria G.
Abnormal Repetitive Behaviour
Ssri
Obsessive-Compulsive
Stress
title_short Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
title_full Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
title_fullStr Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
title_full_unstemmed Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
title_sort Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera)
dc.creator.none.fl_str_mv Galeano, Maria G.
Ruiz, Ruben Daniel
Fiol de Cuneo, Marta
Ponzio, Marina Flavia
author Galeano, Maria G.
author_facet Galeano, Maria G.
Ruiz, Ruben Daniel
Fiol de Cuneo, Marta
Ponzio, Marina Flavia
author_role author
author2 Ruiz, Ruben Daniel
Fiol de Cuneo, Marta
Ponzio, Marina Flavia
author2_role author
author
author
dc.subject.none.fl_str_mv Abnormal Repetitive Behaviour
Ssri
Obsessive-Compulsive
Stress
topic Abnormal Repetitive Behaviour
Ssri
Obsessive-Compulsive
Stress
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Due to its complexity and the relative lack of scientific reports, fur-chewing may be considered as one of the most challenging behavioural problems common to captive chinchillas. The development of this behaviour in commercial farms and the increasing popularity of this species as a pet have increased the public demands for a treatment. The objective of this work was to evaluate the effectiveness of fluoxetine to control the development of chinchillas’ fur-chewing behaviour, using an oral dose of 10 mg/kg/day for a 90 days treatment period. For the measurement of the fur-chewing affected area and its variation during treatment as external sign of whether or not the behaviour was controlled, digital pictures were taken at 0, 45, 75 and 90 days of treatment and after drug withdrawal at 140 days. Results indicated that the greatest difference in percentages of body area affected by the behaviour in control vs. treated animals was observed after 75 days of treatment. However, this was not due to a decrease in the amount of body area affected by fur-chewing in treated animals, but conversely to an increase in the symptoms observed in control animals, that showed a ~10% increase in the fur-chewing affected body area than at the beginning of the experiments. Only ~46% of the fluoxetine treated animals showed a significant reduction in the body area affected by fur-chewing. In summary, the use of fluoxetine in fur-chewing chinchillas showed limited success, mostly reducing the progression of the behaviour.
Fil: Galeano, Maria G.. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Ruiz, Ruben Daniel. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Fiol de Cuneo, Marta. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Ponzio, Marina Flavia. Universidad Nacional de Cordoba. Facultad de Medicina. Departamento de Fisiologia Humana y Fisica Biomedica. Catedra de Fisiologia Humana; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
description Due to its complexity and the relative lack of scientific reports, fur-chewing may be considered as one of the most challenging behavioural problems common to captive chinchillas. The development of this behaviour in commercial farms and the increasing popularity of this species as a pet have increased the public demands for a treatment. The objective of this work was to evaluate the effectiveness of fluoxetine to control the development of chinchillas’ fur-chewing behaviour, using an oral dose of 10 mg/kg/day for a 90 days treatment period. For the measurement of the fur-chewing affected area and its variation during treatment as external sign of whether or not the behaviour was controlled, digital pictures were taken at 0, 45, 75 and 90 days of treatment and after drug withdrawal at 140 days. Results indicated that the greatest difference in percentages of body area affected by the behaviour in control vs. treated animals was observed after 75 days of treatment. However, this was not due to a decrease in the amount of body area affected by fur-chewing in treated animals, but conversely to an increase in the symptoms observed in control animals, that showed a ~10% increase in the fur-chewing affected body area than at the beginning of the experiments. Only ~46% of the fluoxetine treated animals showed a significant reduction in the body area affected by fur-chewing. In summary, the use of fluoxetine in fur-chewing chinchillas showed limited success, mostly reducing the progression of the behaviour.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/11371
Galeano, Maria G.; Ruiz, Ruben Daniel; Fiol de Cuneo, Marta; Ponzio, Marina Flavia; Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera); Elsevier Science; Applied Animal Behaviour Science; 146; 1-4; 6-2013; 112-117
0168-1591
url http://hdl.handle.net/11336/11371
identifier_str_mv Galeano, Maria G.; Ruiz, Ruben Daniel; Fiol de Cuneo, Marta; Ponzio, Marina Flavia; Effectiveness of fluoxetine to control fur-chewing behaviour in the chinchilla (Chinchilla lanigera); Elsevier Science; Applied Animal Behaviour Science; 146; 1-4; 6-2013; 112-117
0168-1591
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.applanim.2013.04.003
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0168159113000993
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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