Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol
- Autores
- José, Carla; Briand, Laura Estefania
- Año de publicación
- 2010
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst which explains its deactivation upon reuses in the esterification reaction.
Fil: José, Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
Fil: Briand, Laura Estefania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina - Materia
-
Ethanol
Ibuprofen
Novozym 435
Biocatalyst - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/3016
Ver los metadatos del registro completo
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spelling |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the AlcoholJosé, CarlaBriand, Laura EstefaniaEthanolIbuprofenNovozym 435Biocatalysthttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2The esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst which explains its deactivation upon reuses in the esterification reaction.Fil: José, Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaFil: Briand, Laura Estefania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaSpringer2010-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/3016José, Carla; Briand, Laura Estefania; Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol; Springer; Reaction Kinetics, Mechanism and Catalysis; 99; 1; 2-2010; 17-221878-51901588-2837enginfo:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.1007/s11144-009-0103-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:30Zoai:ri.conicet.gov.ar:11336/3016instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:30.748CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
title |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
spellingShingle |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol José, Carla Ethanol Ibuprofen Novozym 435 Biocatalyst |
title_short |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
title_full |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
title_fullStr |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
title_full_unstemmed |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
title_sort |
Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol |
dc.creator.none.fl_str_mv |
José, Carla Briand, Laura Estefania |
author |
José, Carla |
author_facet |
José, Carla Briand, Laura Estefania |
author_role |
author |
author2 |
Briand, Laura Estefania |
author2_role |
author |
dc.subject.none.fl_str_mv |
Ethanol Ibuprofen Novozym 435 Biocatalyst |
topic |
Ethanol Ibuprofen Novozym 435 Biocatalyst |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
The esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst which explains its deactivation upon reuses in the esterification reaction. Fil: José, Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina Fil: Briand, Laura Estefania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina |
description |
The esterification of ibuprofen using ethanol as reactant and solvent was investigated. Additionally, the surface interaction of the isomers of ibuprofen and ethanol with the biocatalyst was screened through conventional adsorption isotherms and temperature programmed surface reaction (TPSR). These investigations evidenced strong alcohol adsorption and dissolution of the biocatalyst which explains its deactivation upon reuses in the esterification reaction. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-02 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/3016 José, Carla; Briand, Laura Estefania; Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol; Springer; Reaction Kinetics, Mechanism and Catalysis; 99; 1; 2-2010; 17-22 1878-5190 1588-2837 |
url |
http://hdl.handle.net/11336/3016 |
identifier_str_mv |
José, Carla; Briand, Laura Estefania; Deactivation of Novozym 435 during the Esterification of Ibuprofen with Ethanol: Evidences of the Detrimental Effect of the Alcohol; Springer; Reaction Kinetics, Mechanism and Catalysis; 99; 1; 2-2010; 17-22 1878-5190 1588-2837 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/ info:eu-repo/semantics/altIdentifier/doi/10.1007/s11144-009-0103-4 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1842268671280414720 |
score |
13.13397 |