Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina

Autores
Dvorkin, Julia; Sosa, Emiliano; Vodicka, Elizabeth; Baral, Ranju; Sancilio, Andrea; Dueñas, Karina; Rodriguez, Andrea; Rojas Roque, Carlos; Carruitero, Patricia B.; Polack, Fernando Pedro; Pecenka, Clint; Libster, Romina Paula; Caballero, Mauricio Tomás
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. Methods: This is a prospective cohort study that collected information regarding 256 infants under 12 months of age with acute lower respiratory tract infection (ALRTI) due to RSV in two public hospitals of Buenos Aires between 2014 and 2016. Information on healthcare resource use was collected from the patient’s report and its associated costs were estimated based on the financial database and account records of the hospitals. We estimated the total cost per hospitalization due to RSV using the health system perspective. The costs were estimated in US dollars as of December 2022 (1 US dollar = 170 Argentine pesos).Results:The mean costs per RSV hospitalization in infants was US$587.79 (95% confidence interval [CI] $535.24 – $640.33). The mean costs associated with pediatric intensive care unit (PICU) admission more than doubled from those at regular pediatric wards ($1,556.81 [95% CI $512.21 – $2,601.40] versus $556.53 [95% CI $514.59 – $598.48]).Conclusions:This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed.
Fil: Dvorkin, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina. Universidad Nacional de San Martín; Argentina
Fil: Sosa, Emiliano. Universidad Nacional de San Martín; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Vodicka, Elizabeth. No especifíca;
Fil: Baral, Ranju. No especifíca;
Fil: Sancilio, Andrea. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Dueñas, Karina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Rodriguez, Andrea. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Rojas Roque, Carlos. No especifíca;
Fil: Carruitero, Patricia B.. Universidad Nacional de La Plata. Facultad de Ciencias Económicas; Argentina
Fil: Polack, Fernando Pedro. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Pecenka, Clint. No especifíca;
Fil: Libster, Romina Paula. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Caballero, Mauricio Tomás. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
Materia
Virus sincicial respiratorio
carga economica
hospitalizaciones
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/236508
Acceder
id CONICETDig_6447067bf62429cb884ac535adac57d6
oai_identifier_str oai:ri.conicet.gov.ar:11336/236508
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in ArgentinaDvorkin, JuliaSosa, EmilianoVodicka, ElizabethBaral, RanjuSancilio, AndreaDueñas, KarinaRodriguez, AndreaRojas Roque, CarlosCarruitero, Patricia B.Polack, Fernando PedroPecenka, ClintLibster, Romina PaulaCaballero, Mauricio TomásVirus sincicial respiratoriocarga economicahospitalizacioneshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. Methods: This is a prospective cohort study that collected information regarding 256 infants under 12 months of age with acute lower respiratory tract infection (ALRTI) due to RSV in two public hospitals of Buenos Aires between 2014 and 2016. Information on healthcare resource use was collected from the patient’s report and its associated costs were estimated based on the financial database and account records of the hospitals. We estimated the total cost per hospitalization due to RSV using the health system perspective. The costs were estimated in US dollars as of December 2022 (1 US dollar = 170 Argentine pesos).Results:The mean costs per RSV hospitalization in infants was US$587.79 (95% confidence interval [CI] $535.24 – $640.33). The mean costs associated with pediatric intensive care unit (PICU) admission more than doubled from those at regular pediatric wards ($1,556.81 [95% CI $512.21 – $2,601.40] versus $556.53 [95% CI $514.59 – $598.48]).Conclusions:This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed.Fil: Dvorkin, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina. Universidad Nacional de San Martín; ArgentinaFil: Sosa, Emiliano. Universidad Nacional de San Martín; Argentina. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Vodicka, Elizabeth. No especifíca;Fil: Baral, Ranju. No especifíca;Fil: Sancilio, Andrea. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Dueñas, Karina. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Rodriguez, Andrea. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Rojas Roque, Carlos. No especifíca;Fil: Carruitero, Patricia B.. Universidad Nacional de La Plata. Facultad de Ciencias Económicas; ArgentinaFil: Polack, Fernando Pedro. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Pecenka, Clint. No especifíca;Fil: Libster, Romina Paula. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; ArgentinaFil: Caballero, Mauricio Tomás. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; ArgentinaBioMed Central2024-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/236508Dvorkin, Julia; Sosa, Emiliano; Vodicka, Elizabeth ; Baral, Ranju; Sancilio, Andrea ; et al.; Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina; BioMed Central; BMC Public Health; 24; 1; 2-2024; 1-91471-2458CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-024-17878-3info:eu-repo/semantics/altIdentifier/doi/10.1186/s12889-024-17878-3info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:09:00Zoai:ri.conicet.gov.ar:11336/236508instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:09:00.425CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
title Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
spellingShingle Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
Dvorkin, Julia
Virus sincicial respiratorio
carga economica
hospitalizaciones
title_short Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
title_full Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
title_fullStr Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
title_full_unstemmed Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
title_sort Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina
dc.creator.none.fl_str_mv Dvorkin, Julia
Sosa, Emiliano
Vodicka, Elizabeth
Baral, Ranju
Sancilio, Andrea
Dueñas, Karina
Rodriguez, Andrea
Rojas Roque, Carlos
Carruitero, Patricia B.
Polack, Fernando Pedro
Pecenka, Clint
Libster, Romina Paula
Caballero, Mauricio Tomás
author Dvorkin, Julia
author_facet Dvorkin, Julia
Sosa, Emiliano
Vodicka, Elizabeth
Baral, Ranju
Sancilio, Andrea
Dueñas, Karina
Rodriguez, Andrea
Rojas Roque, Carlos
Carruitero, Patricia B.
Polack, Fernando Pedro
Pecenka, Clint
Libster, Romina Paula
Caballero, Mauricio Tomás
author_role author
author2 Sosa, Emiliano
Vodicka, Elizabeth
Baral, Ranju
Sancilio, Andrea
Dueñas, Karina
Rodriguez, Andrea
Rojas Roque, Carlos
Carruitero, Patricia B.
Polack, Fernando Pedro
Pecenka, Clint
Libster, Romina Paula
Caballero, Mauricio Tomás
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Virus sincicial respiratorio
carga economica
hospitalizaciones
topic Virus sincicial respiratorio
carga economica
hospitalizaciones
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. Methods: This is a prospective cohort study that collected information regarding 256 infants under 12 months of age with acute lower respiratory tract infection (ALRTI) due to RSV in two public hospitals of Buenos Aires between 2014 and 2016. Information on healthcare resource use was collected from the patient’s report and its associated costs were estimated based on the financial database and account records of the hospitals. We estimated the total cost per hospitalization due to RSV using the health system perspective. The costs were estimated in US dollars as of December 2022 (1 US dollar = 170 Argentine pesos).Results:The mean costs per RSV hospitalization in infants was US$587.79 (95% confidence interval [CI] $535.24 – $640.33). The mean costs associated with pediatric intensive care unit (PICU) admission more than doubled from those at regular pediatric wards ($1,556.81 [95% CI $512.21 – $2,601.40] versus $556.53 [95% CI $514.59 – $598.48]).Conclusions:This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed.
Fil: Dvorkin, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina. Universidad Nacional de San Martín; Argentina
Fil: Sosa, Emiliano. Universidad Nacional de San Martín; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Vodicka, Elizabeth. No especifíca;
Fil: Baral, Ranju. No especifíca;
Fil: Sancilio, Andrea. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Dueñas, Karina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Rodriguez, Andrea. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Rojas Roque, Carlos. No especifíca;
Fil: Carruitero, Patricia B.. Universidad Nacional de La Plata. Facultad de Ciencias Económicas; Argentina
Fil: Polack, Fernando Pedro. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Pecenka, Clint. No especifíca;
Fil: Libster, Romina Paula. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
Fil: Caballero, Mauricio Tomás. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Investigación en Infectología Infantil; Argentina
description Background: Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. Methods: This is a prospective cohort study that collected information regarding 256 infants under 12 months of age with acute lower respiratory tract infection (ALRTI) due to RSV in two public hospitals of Buenos Aires between 2014 and 2016. Information on healthcare resource use was collected from the patient’s report and its associated costs were estimated based on the financial database and account records of the hospitals. We estimated the total cost per hospitalization due to RSV using the health system perspective. The costs were estimated in US dollars as of December 2022 (1 US dollar = 170 Argentine pesos).Results:The mean costs per RSV hospitalization in infants was US$587.79 (95% confidence interval [CI] $535.24 – $640.33). The mean costs associated with pediatric intensive care unit (PICU) admission more than doubled from those at regular pediatric wards ($1,556.81 [95% CI $512.21 – $2,601.40] versus $556.53 [95% CI $514.59 – $598.48]).Conclusions:This study shows the direct economic impact of acute severe RSV infection on the public health system in Argentina. The estimates obtained from this study could be used to inform cost-effectiveness analyses of new preventive RSV interventions being developed.
publishDate 2024
dc.date.none.fl_str_mv 2024-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/236508
Dvorkin, Julia; Sosa, Emiliano; Vodicka, Elizabeth ; Baral, Ranju; Sancilio, Andrea ; et al.; Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina; BioMed Central; BMC Public Health; 24; 1; 2-2024; 1-9
1471-2458
CONICET Digital
CONICET
url http://hdl.handle.net/11336/236508
identifier_str_mv Dvorkin, Julia; Sosa, Emiliano; Vodicka, Elizabeth ; Baral, Ranju; Sancilio, Andrea ; et al.; Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina; BioMed Central; BMC Public Health; 24; 1; 2-2024; 1-9
1471-2458
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-024-17878-3
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12889-024-17878-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613963935907840
score 13.070432

Publicaciones similares