Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels

Autores
Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A water soluble cationic metal complex (tris(2,2'-bipyridine)ruthenium(II)) can be loaded into hydrogels containing acrylamide and/or acrylic acid units. The cationic complex is retained in polymer containing acrylic acid units at high pH and released at low pH. This is likely due to electrostatic interactions of the cation with the carboxylate anions, present at high pH, which are converted into neutral carboxylic acid at low pH, releasing the metal complex. Since the gel contract at low pH, the water soluble cation is also released with the water expelled from the gel. However, a strong retention of the cation inside the gels is observed when acrylamide units are present. A possible explanation is a hydrophobic interaction of the large metal complex with the polyacrylamide network. Using the counteracting electrostatic and hydrophobic interactions of probe molecules with smart hydrogel matrixes it is possible to tune the pH of maximum release away from the pKa of the ionizable group.
Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Materia
CATIONIC COMPLEX
HYDROGELS
HYDROPHOBIC INTERACTION
METAL COMPLEX
POLYACRYLAMIDE NETWORK
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/131347
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogelsMolina, María AlejandraRivarola, Claudia RosanaBarbero, César AlfredoCATIONIC COMPLEXHYDROGELSHYDROPHOBIC INTERACTIONMETAL COMPLEXPOLYACRYLAMIDE NETWORKhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A water soluble cationic metal complex (tris(2,2'-bipyridine)ruthenium(II)) can be loaded into hydrogels containing acrylamide and/or acrylic acid units. The cationic complex is retained in polymer containing acrylic acid units at high pH and released at low pH. This is likely due to electrostatic interactions of the cation with the carboxylate anions, present at high pH, which are converted into neutral carboxylic acid at low pH, releasing the metal complex. Since the gel contract at low pH, the water soluble cation is also released with the water expelled from the gel. However, a strong retention of the cation inside the gels is observed when acrylamide units are present. A possible explanation is a hydrophobic interaction of the large metal complex with the polyacrylamide network. Using the counteracting electrostatic and hydrophobic interactions of probe molecules with smart hydrogel matrixes it is possible to tune the pH of maximum release away from the pKa of the ionizable group.Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaTaylor & Francis Ltd2010-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/131347Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels; Taylor & Francis Ltd; Molecular Crystals and Liquid Crystals - (Print); 521; 1-2010; 265-2711563-52871542-1406CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/15421401003722732info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/15421401003722732info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T11:39:51Zoai:ri.conicet.gov.ar:11336/131347instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 11:39:51.784CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
title Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
spellingShingle Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
Molina, María Alejandra
CATIONIC COMPLEX
HYDROGELS
HYDROPHOBIC INTERACTION
METAL COMPLEX
POLYACRYLAMIDE NETWORK
title_short Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
title_full Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
title_fullStr Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
title_full_unstemmed Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
title_sort Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels
dc.creator.none.fl_str_mv Molina, María Alejandra
Rivarola, Claudia Rosana
Barbero, César Alfredo
author Molina, María Alejandra
author_facet Molina, María Alejandra
Rivarola, Claudia Rosana
Barbero, César Alfredo
author_role author
author2 Rivarola, Claudia Rosana
Barbero, César Alfredo
author2_role author
author
dc.subject.none.fl_str_mv CATIONIC COMPLEX
HYDROGELS
HYDROPHOBIC INTERACTION
METAL COMPLEX
POLYACRYLAMIDE NETWORK
topic CATIONIC COMPLEX
HYDROGELS
HYDROPHOBIC INTERACTION
METAL COMPLEX
POLYACRYLAMIDE NETWORK
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A water soluble cationic metal complex (tris(2,2'-bipyridine)ruthenium(II)) can be loaded into hydrogels containing acrylamide and/or acrylic acid units. The cationic complex is retained in polymer containing acrylic acid units at high pH and released at low pH. This is likely due to electrostatic interactions of the cation with the carboxylate anions, present at high pH, which are converted into neutral carboxylic acid at low pH, releasing the metal complex. Since the gel contract at low pH, the water soluble cation is also released with the water expelled from the gel. However, a strong retention of the cation inside the gels is observed when acrylamide units are present. A possible explanation is a hydrophobic interaction of the large metal complex with the polyacrylamide network. Using the counteracting electrostatic and hydrophobic interactions of probe molecules with smart hydrogel matrixes it is possible to tune the pH of maximum release away from the pKa of the ionizable group.
Fil: Molina, María Alejandra. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Rivarola, Claudia Rosana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Barbero, César Alfredo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
description A water soluble cationic metal complex (tris(2,2'-bipyridine)ruthenium(II)) can be loaded into hydrogels containing acrylamide and/or acrylic acid units. The cationic complex is retained in polymer containing acrylic acid units at high pH and released at low pH. This is likely due to electrostatic interactions of the cation with the carboxylate anions, present at high pH, which are converted into neutral carboxylic acid at low pH, releasing the metal complex. Since the gel contract at low pH, the water soluble cation is also released with the water expelled from the gel. However, a strong retention of the cation inside the gels is observed when acrylamide units are present. A possible explanation is a hydrophobic interaction of the large metal complex with the polyacrylamide network. Using the counteracting electrostatic and hydrophobic interactions of probe molecules with smart hydrogel matrixes it is possible to tune the pH of maximum release away from the pKa of the ionizable group.
publishDate 2010
dc.date.none.fl_str_mv 2010-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/131347
Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels; Taylor & Francis Ltd; Molecular Crystals and Liquid Crystals - (Print); 521; 1-2010; 265-271
1563-5287
1542-1406
CONICET Digital
CONICET
url http://hdl.handle.net/11336/131347
identifier_str_mv Molina, María Alejandra; Rivarola, Claudia Rosana; Barbero, César Alfredo; Evidence of hydrophobic interactions controlling mobile ions release from smart hydrogels; Taylor & Francis Ltd; Molecular Crystals and Liquid Crystals - (Print); 521; 1-2010; 265-271
1563-5287
1542-1406
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1080/15421401003722732
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/15421401003722732
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis Ltd
publisher.none.fl_str_mv Taylor & Francis Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1843606755949412352
score 13.000565

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