Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments

Autores
Guzmán, Maricel; Steffan, Pedro Eduardo; Riva, Eliana; Bernat, Gisele; Scarcella, Silvana Andrea; Murno, Graciela; Giudici, Claudio; Rodríguez, Edgardo; Fiel, Cesar Alberto
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In order to evaluate the potential risk of Haemonchus contortus resistant to benzimidazole (BZ) treatments to pass from sheep to cattle a series of experiments were carried out. Two field isolates of H. contortus resistant (Ayacucho) or susceptible (Cedive) to BZ treatments were reproduced in lambs and involved in the study. Two groups of 4 calves each and two groups of 4 lambs each were infected with larvae (L3) of each isolate respectively. The number of eggs in faeces (EPG), worm count and ratio of worm establishment (RWE) were determined. The number of red blood cells, packed cell volume and haemoglobin concentration was assessed. The EPG levels were higher for Ayacucho isolate which reached to a peak of 7,168 and 780 at day 42 post inoculation (PI) in lambs and calves respectively. The RWE at day 45 PI was 28.8 % and 7.16% for Ayacucho isolate in lambs and calves respectively while for Cedive isolate was 36.6% and 0.04% respectively. At day 90 PI the RWE was of 1.94% and 0.69% in lambs for Ayacucho and Cedive isolate respectively, whereas no worms were recovered from calves. The haematological parameters in lambs and calves did not show significant differences between isolates. The present studies demonstrate that some populations of H. contortus may complete life cycle in calves and remain established for at least a 45 days period PI. This finding should be strongly considered when farm production involves mixed or alternate sheep/cattle grazing and backgrounds of anthelmintic resistance.
Fil: Guzmán, Maricel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
Fil: Steffan, Pedro Eduardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
Fil: Riva, Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Bernat, Gisele. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Scarcella, Silvana Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Laboratorio de Biología Celular y Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Murno, Graciela. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Giudici, Claudio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina
Fil: Rodríguez, Edgardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Fiel, Cesar Alberto. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
Materia
HAEMONCHUS
ANTHELMINTIC RESISTANCE
EXPERIMENTAL INFECTIONS
MANAGEMENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/58558
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole TreatmentsGuzmán, MaricelSteffan, Pedro EduardoRiva, ElianaBernat, GiseleScarcella, Silvana AndreaMurno, GracielaGiudici, ClaudioRodríguez, EdgardoFiel, Cesar AlbertoHAEMONCHUSANTHELMINTIC RESISTANCEEXPERIMENTAL INFECTIONSMANAGEMENThttps://purl.org/becyt/ford/4.2https://purl.org/becyt/ford/4In order to evaluate the potential risk of Haemonchus contortus resistant to benzimidazole (BZ) treatments to pass from sheep to cattle a series of experiments were carried out. Two field isolates of H. contortus resistant (Ayacucho) or susceptible (Cedive) to BZ treatments were reproduced in lambs and involved in the study. Two groups of 4 calves each and two groups of 4 lambs each were infected with larvae (L3) of each isolate respectively. The number of eggs in faeces (EPG), worm count and ratio of worm establishment (RWE) were determined. The number of red blood cells, packed cell volume and haemoglobin concentration was assessed. The EPG levels were higher for Ayacucho isolate which reached to a peak of 7,168 and 780 at day 42 post inoculation (PI) in lambs and calves respectively. The RWE at day 45 PI was 28.8 % and 7.16% for Ayacucho isolate in lambs and calves respectively while for Cedive isolate was 36.6% and 0.04% respectively. At day 90 PI the RWE was of 1.94% and 0.69% in lambs for Ayacucho and Cedive isolate respectively, whereas no worms were recovered from calves. The haematological parameters in lambs and calves did not show significant differences between isolates. The present studies demonstrate that some populations of H. contortus may complete life cycle in calves and remain established for at least a 45 days period PI. This finding should be strongly considered when farm production involves mixed or alternate sheep/cattle grazing and backgrounds of anthelmintic resistance.Fil: Guzmán, Maricel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; ArgentinaFil: Steffan, Pedro Eduardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; ArgentinaFil: Riva, Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Bernat, Gisele. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Scarcella, Silvana Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Laboratorio de Biología Celular y Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Murno, Graciela. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Giudici, Claudio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; ArgentinaFil: Rodríguez, Edgardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Fiel, Cesar Alberto. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; ArgentinaJSciMed Central2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/58558Guzmán, Maricel; Steffan, Pedro Eduardo; Riva, Eliana; Bernat, Gisele; Scarcella, Silvana Andrea; et al.; Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments; JSciMed Central; Journal of Veterinary Medicine and Research; 4; 3; 3-2017; 1-5; 10762378-931XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.jscimedcentral.com/VeterinaryMedicine/veterinarymedicine-4-1076.pdfinfo:eu-repo/semantics/altIdentifier/url/https://www.jscimedcentral.com/VeterinaryMedicine/vol4issue3.phpinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:23:48Zoai:ri.conicet.gov.ar:11336/58558instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:23:49.271CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
title Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
spellingShingle Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
Guzmán, Maricel
HAEMONCHUS
ANTHELMINTIC RESISTANCE
EXPERIMENTAL INFECTIONS
MANAGEMENT
title_short Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
title_full Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
title_fullStr Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
title_full_unstemmed Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
title_sort Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments
dc.creator.none.fl_str_mv Guzmán, Maricel
Steffan, Pedro Eduardo
Riva, Eliana
Bernat, Gisele
Scarcella, Silvana Andrea
Murno, Graciela
Giudici, Claudio
Rodríguez, Edgardo
Fiel, Cesar Alberto
author Guzmán, Maricel
author_facet Guzmán, Maricel
Steffan, Pedro Eduardo
Riva, Eliana
Bernat, Gisele
Scarcella, Silvana Andrea
Murno, Graciela
Giudici, Claudio
Rodríguez, Edgardo
Fiel, Cesar Alberto
author_role author
author2 Steffan, Pedro Eduardo
Riva, Eliana
Bernat, Gisele
Scarcella, Silvana Andrea
Murno, Graciela
Giudici, Claudio
Rodríguez, Edgardo
Fiel, Cesar Alberto
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv HAEMONCHUS
ANTHELMINTIC RESISTANCE
EXPERIMENTAL INFECTIONS
MANAGEMENT
topic HAEMONCHUS
ANTHELMINTIC RESISTANCE
EXPERIMENTAL INFECTIONS
MANAGEMENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.2
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv In order to evaluate the potential risk of Haemonchus contortus resistant to benzimidazole (BZ) treatments to pass from sheep to cattle a series of experiments were carried out. Two field isolates of H. contortus resistant (Ayacucho) or susceptible (Cedive) to BZ treatments were reproduced in lambs and involved in the study. Two groups of 4 calves each and two groups of 4 lambs each were infected with larvae (L3) of each isolate respectively. The number of eggs in faeces (EPG), worm count and ratio of worm establishment (RWE) were determined. The number of red blood cells, packed cell volume and haemoglobin concentration was assessed. The EPG levels were higher for Ayacucho isolate which reached to a peak of 7,168 and 780 at day 42 post inoculation (PI) in lambs and calves respectively. The RWE at day 45 PI was 28.8 % and 7.16% for Ayacucho isolate in lambs and calves respectively while for Cedive isolate was 36.6% and 0.04% respectively. At day 90 PI the RWE was of 1.94% and 0.69% in lambs for Ayacucho and Cedive isolate respectively, whereas no worms were recovered from calves. The haematological parameters in lambs and calves did not show significant differences between isolates. The present studies demonstrate that some populations of H. contortus may complete life cycle in calves and remain established for at least a 45 days period PI. This finding should be strongly considered when farm production involves mixed or alternate sheep/cattle grazing and backgrounds of anthelmintic resistance.
Fil: Guzmán, Maricel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
Fil: Steffan, Pedro Eduardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
Fil: Riva, Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Bernat, Gisele. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Scarcella, Silvana Andrea. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Laboratorio de Biología Celular y Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Murno, Graciela. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Giudici, Claudio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina
Fil: Rodríguez, Edgardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
Fil: Fiel, Cesar Alberto. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva. Area Parasitología y Enfermedades Parasitarias; Argentina
description In order to evaluate the potential risk of Haemonchus contortus resistant to benzimidazole (BZ) treatments to pass from sheep to cattle a series of experiments were carried out. Two field isolates of H. contortus resistant (Ayacucho) or susceptible (Cedive) to BZ treatments were reproduced in lambs and involved in the study. Two groups of 4 calves each and two groups of 4 lambs each were infected with larvae (L3) of each isolate respectively. The number of eggs in faeces (EPG), worm count and ratio of worm establishment (RWE) were determined. The number of red blood cells, packed cell volume and haemoglobin concentration was assessed. The EPG levels were higher for Ayacucho isolate which reached to a peak of 7,168 and 780 at day 42 post inoculation (PI) in lambs and calves respectively. The RWE at day 45 PI was 28.8 % and 7.16% for Ayacucho isolate in lambs and calves respectively while for Cedive isolate was 36.6% and 0.04% respectively. At day 90 PI the RWE was of 1.94% and 0.69% in lambs for Ayacucho and Cedive isolate respectively, whereas no worms were recovered from calves. The haematological parameters in lambs and calves did not show significant differences between isolates. The present studies demonstrate that some populations of H. contortus may complete life cycle in calves and remain established for at least a 45 days period PI. This finding should be strongly considered when farm production involves mixed or alternate sheep/cattle grazing and backgrounds of anthelmintic resistance.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/58558
Guzmán, Maricel; Steffan, Pedro Eduardo; Riva, Eliana; Bernat, Gisele; Scarcella, Silvana Andrea; et al.; Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments; JSciMed Central; Journal of Veterinary Medicine and Research; 4; 3; 3-2017; 1-5; 1076
2378-931X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/58558
identifier_str_mv Guzmán, Maricel; Steffan, Pedro Eduardo; Riva, Eliana; Bernat, Gisele; Scarcella, Silvana Andrea; et al.; Experimental Infections in Cattle and Sheep with Haemonchus contortus Resistant or Susceptible to Benzimidazole Treatments; JSciMed Central; Journal of Veterinary Medicine and Research; 4; 3; 3-2017; 1-5; 1076
2378-931X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/url/https://www.jscimedcentral.com/VeterinaryMedicine/vol4issue3.php
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
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dc.publisher.none.fl_str_mv JSciMed Central
publisher.none.fl_str_mv JSciMed Central
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reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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