High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
- Autores
- García, Angelina; Demarchi, Dario; Tovo Rodrigues, Luciana; Pauro, Maia; Callegari Jacques, Sidia M.; Salzano, Francisco M.; Hutz, Mara H.
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.
Fil: García, Angelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
Fil: Demarchi, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
Fil: Tovo Rodrigues, Luciana. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Pauro, Maia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
Fil: Callegari Jacques, Sidia M.. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Hutz, Mara H.. Universidade Federal do Rio Grande do Sul; Brasil - Materia
-
AIMs
CÓRDOBA
MIGRATIONS
POPULATION STRUCTURE
SAN LUIS - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/11103
Ver los metadatos del registro completo
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CONICET Digital (CONICET) |
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High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)García, AngelinaDemarchi, DarioTovo Rodrigues, LucianaPauro, MaiaCallegari Jacques, Sidia M.Salzano, Francisco M.Hutz, Mara H.AIMsCÓRDOBAMIGRATIONSPOPULATION STRUCTURESAN LUIShttps://purl.org/becyt/ford/6.5https://purl.org/becyt/ford/6https://purl.org/becyt/ford/6.5https://purl.org/becyt/ford/6The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.Fil: García, Angelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; ArgentinaFil: Demarchi, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; ArgentinaFil: Tovo Rodrigues, Luciana. Universidade Federal do Rio Grande do Sul; BrasilFil: Pauro, Maia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; ArgentinaFil: Callegari Jacques, Sidia M.. Universidade Federal do Rio Grande do Sul; BrasilFil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; BrasilFil: Hutz, Mara H.. Universidade Federal do Rio Grande do Sul; BrasilSociedade Brasileira de Genética2015-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11103García, Angelina; Demarchi, Dario; Tovo Rodrigues, Luciana; Pauro, Maia; Callegari Jacques, Sidia M.; et al.; High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs); Sociedade Brasileira de Genética; Genetics And Molecular Biology; 38; 3; 7-2015; 324-3311415-47571678-4685enginfo:eu-repo/semantics/altIdentifier/doi/10.1590/S1415-475738320140260info:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/pnsddsinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26500436/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:42:16Zoai:ri.conicet.gov.ar:11336/11103instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:42:16.564CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
title |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
spellingShingle |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) García, Angelina AIMs CÓRDOBA MIGRATIONS POPULATION STRUCTURE SAN LUIS |
title_short |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
title_full |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
title_fullStr |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
title_full_unstemmed |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
title_sort |
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs) |
dc.creator.none.fl_str_mv |
García, Angelina Demarchi, Dario Tovo Rodrigues, Luciana Pauro, Maia Callegari Jacques, Sidia M. Salzano, Francisco M. Hutz, Mara H. |
author |
García, Angelina |
author_facet |
García, Angelina Demarchi, Dario Tovo Rodrigues, Luciana Pauro, Maia Callegari Jacques, Sidia M. Salzano, Francisco M. Hutz, Mara H. |
author_role |
author |
author2 |
Demarchi, Dario Tovo Rodrigues, Luciana Pauro, Maia Callegari Jacques, Sidia M. Salzano, Francisco M. Hutz, Mara H. |
author2_role |
author author author author author author |
dc.subject.none.fl_str_mv |
AIMs CÓRDOBA MIGRATIONS POPULATION STRUCTURE SAN LUIS |
topic |
AIMs CÓRDOBA MIGRATIONS POPULATION STRUCTURE SAN LUIS |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/6.5 https://purl.org/becyt/ford/6 https://purl.org/becyt/ford/6.5 https://purl.org/becyt/ford/6 |
dc.description.none.fl_txt_mv |
The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow. Fil: García, Angelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina Fil: Demarchi, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina Fil: Tovo Rodrigues, Luciana. Universidade Federal do Rio Grande do Sul; Brasil Fil: Pauro, Maia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina Fil: Callegari Jacques, Sidia M.. Universidade Federal do Rio Grande do Sul; Brasil Fil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil Fil: Hutz, Mara H.. Universidade Federal do Rio Grande do Sul; Brasil |
description |
The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-07 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/11103 García, Angelina; Demarchi, Dario; Tovo Rodrigues, Luciana; Pauro, Maia; Callegari Jacques, Sidia M.; et al.; High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs); Sociedade Brasileira de Genética; Genetics And Molecular Biology; 38; 3; 7-2015; 324-331 1415-4757 1678-4685 |
url |
http://hdl.handle.net/11336/11103 |
identifier_str_mv |
García, Angelina; Demarchi, Dario; Tovo Rodrigues, Luciana; Pauro, Maia; Callegari Jacques, Sidia M.; et al.; High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs); Sociedade Brasileira de Genética; Genetics And Molecular Biology; 38; 3; 7-2015; 324-331 1415-4757 1678-4685 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1590/S1415-475738320140260 info:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/pnsdds info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26500436/ |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1846083531447468032 |
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13.22299 |