Weight gain as a potential risk factor in kidney stones formers

Autores
Moyano, Mario Franco; Wendel, Graciela Haydée; Trujillo, Liliana del Carmen; Orellano, Guillermo Osvaldo; Fuentes, Lucia Beatriz
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The prevalence of kidney stones is increasing and obesity has reaching epidemic proportions. The aim was to investigate whether obesity influences the kidney stone forming. 421 patients, 31.6% women and 41.6% men were overweight (OV), and 25% and 9.6% were obese (OB), respectively. Serum uric acid increased significantly OB women(p<0.001), differences between gender(p<0.001). Creatinine increased in OB men(p<0.05), and men respect to women(p < 0.001), urea between OB women and men(p<0.05). PTH increased in OB women(p<0.05). Urinary excretion phosphorus(p<0.05), uric acid(p<0.01) increased in OB women. Creatinine clearance was higher in OB both sexes(p<0.05), and differences compared women to men(p<0.001). BMI was positively correlated with serum uric acid, sodium, potassium and PTH in both sexes and urinary uric acid excretion, calcium, sodium, phosphate in women and oxalic acid in both sexes. Glomerular filtration rate, urine specific gravity and pH were inversely related to BMI. Uric acid is main stone constituent in obese women(86.36%) and overweight men(86.66%). In conclusion, higher body weight could be associated with an increased risk of renal stone forming and some metabolic gender differences were found.
Fil: Moyano, Mario Franco. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Wendel, Graciela Haydée. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Trujillo, Liliana del Carmen. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Orellano, Guillermo Osvaldo. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Fuentes, Lucia Beatriz. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Materia
Nephrolithiasis
Obesity
Metabolic Studies
Uric Acid Stones
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/69824
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Weight gain as a potential risk factor in kidney stones formersMoyano, Mario FrancoWendel, Graciela HaydéeTrujillo, Liliana del CarmenOrellano, Guillermo OsvaldoFuentes, Lucia BeatrizNephrolithiasisObesityMetabolic StudiesUric Acid Stoneshttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The prevalence of kidney stones is increasing and obesity has reaching epidemic proportions. The aim was to investigate whether obesity influences the kidney stone forming. 421 patients, 31.6% women and 41.6% men were overweight (OV), and 25% and 9.6% were obese (OB), respectively. Serum uric acid increased significantly OB women(p<0.001), differences between gender(p<0.001). Creatinine increased in OB men(p<0.05), and men respect to women(p < 0.001), urea between OB women and men(p<0.05). PTH increased in OB women(p<0.05). Urinary excretion phosphorus(p<0.05), uric acid(p<0.01) increased in OB women. Creatinine clearance was higher in OB both sexes(p<0.05), and differences compared women to men(p<0.001). BMI was positively correlated with serum uric acid, sodium, potassium and PTH in both sexes and urinary uric acid excretion, calcium, sodium, phosphate in women and oxalic acid in both sexes. Glomerular filtration rate, urine specific gravity and pH were inversely related to BMI. Uric acid is main stone constituent in obese women(86.36%) and overweight men(86.66%). In conclusion, higher body weight could be associated with an increased risk of renal stone forming and some metabolic gender differences were found.Fil: Moyano, Mario Franco. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Wendel, Graciela Haydée. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Trujillo, Liliana del Carmen. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Orellano, Guillermo Osvaldo. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaFil: Fuentes, Lucia Beatriz. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; ArgentinaEuropean Centre for Research Training and Development2015-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/69824Moyano, Mario Franco; Wendel, Graciela Haydée; Trujillo, Liliana del Carmen; Orellano, Guillermo Osvaldo; Fuentes, Lucia Beatriz; Weight gain as a potential risk factor in kidney stones formers; European Centre for Research Training and Development; International Research Journal of Natural Sciences; 3; 4; 12-2015; 54-652053-41082053-4116CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.eajournals.org/wp-content/uploads/Weight-Gain-as-a-Potential-Risk-Factor-In-Kidney-Stones-Formers.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-01-08T13:12:04Zoai:ri.conicet.gov.ar:11336/69824instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-01-08 13:12:04.24CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Weight gain as a potential risk factor in kidney stones formers
title Weight gain as a potential risk factor in kidney stones formers
spellingShingle Weight gain as a potential risk factor in kidney stones formers
Moyano, Mario Franco
Nephrolithiasis
Obesity
Metabolic Studies
Uric Acid Stones
title_short Weight gain as a potential risk factor in kidney stones formers
title_full Weight gain as a potential risk factor in kidney stones formers
title_fullStr Weight gain as a potential risk factor in kidney stones formers
title_full_unstemmed Weight gain as a potential risk factor in kidney stones formers
title_sort Weight gain as a potential risk factor in kidney stones formers
dc.creator.none.fl_str_mv Moyano, Mario Franco
Wendel, Graciela Haydée
Trujillo, Liliana del Carmen
Orellano, Guillermo Osvaldo
Fuentes, Lucia Beatriz
author Moyano, Mario Franco
author_facet Moyano, Mario Franco
Wendel, Graciela Haydée
Trujillo, Liliana del Carmen
Orellano, Guillermo Osvaldo
Fuentes, Lucia Beatriz
author_role author
author2 Wendel, Graciela Haydée
Trujillo, Liliana del Carmen
Orellano, Guillermo Osvaldo
Fuentes, Lucia Beatriz
author2_role author
author
author
author
dc.subject.none.fl_str_mv Nephrolithiasis
Obesity
Metabolic Studies
Uric Acid Stones
topic Nephrolithiasis
Obesity
Metabolic Studies
Uric Acid Stones
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The prevalence of kidney stones is increasing and obesity has reaching epidemic proportions. The aim was to investigate whether obesity influences the kidney stone forming. 421 patients, 31.6% women and 41.6% men were overweight (OV), and 25% and 9.6% were obese (OB), respectively. Serum uric acid increased significantly OB women(p<0.001), differences between gender(p<0.001). Creatinine increased in OB men(p<0.05), and men respect to women(p < 0.001), urea between OB women and men(p<0.05). PTH increased in OB women(p<0.05). Urinary excretion phosphorus(p<0.05), uric acid(p<0.01) increased in OB women. Creatinine clearance was higher in OB both sexes(p<0.05), and differences compared women to men(p<0.001). BMI was positively correlated with serum uric acid, sodium, potassium and PTH in both sexes and urinary uric acid excretion, calcium, sodium, phosphate in women and oxalic acid in both sexes. Glomerular filtration rate, urine specific gravity and pH were inversely related to BMI. Uric acid is main stone constituent in obese women(86.36%) and overweight men(86.66%). In conclusion, higher body weight could be associated with an increased risk of renal stone forming and some metabolic gender differences were found.
Fil: Moyano, Mario Franco. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Wendel, Graciela Haydée. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Trujillo, Liliana del Carmen. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Orellano, Guillermo Osvaldo. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
Fil: Fuentes, Lucia Beatriz. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
description The prevalence of kidney stones is increasing and obesity has reaching epidemic proportions. The aim was to investigate whether obesity influences the kidney stone forming. 421 patients, 31.6% women and 41.6% men were overweight (OV), and 25% and 9.6% were obese (OB), respectively. Serum uric acid increased significantly OB women(p<0.001), differences between gender(p<0.001). Creatinine increased in OB men(p<0.05), and men respect to women(p < 0.001), urea between OB women and men(p<0.05). PTH increased in OB women(p<0.05). Urinary excretion phosphorus(p<0.05), uric acid(p<0.01) increased in OB women. Creatinine clearance was higher in OB both sexes(p<0.05), and differences compared women to men(p<0.001). BMI was positively correlated with serum uric acid, sodium, potassium and PTH in both sexes and urinary uric acid excretion, calcium, sodium, phosphate in women and oxalic acid in both sexes. Glomerular filtration rate, urine specific gravity and pH were inversely related to BMI. Uric acid is main stone constituent in obese women(86.36%) and overweight men(86.66%). In conclusion, higher body weight could be associated with an increased risk of renal stone forming and some metabolic gender differences were found.
publishDate 2015
dc.date.none.fl_str_mv 2015-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/69824
Moyano, Mario Franco; Wendel, Graciela Haydée; Trujillo, Liliana del Carmen; Orellano, Guillermo Osvaldo; Fuentes, Lucia Beatriz; Weight gain as a potential risk factor in kidney stones formers; European Centre for Research Training and Development; International Research Journal of Natural Sciences; 3; 4; 12-2015; 54-65
2053-4108
2053-4116
CONICET Digital
CONICET
url http://hdl.handle.net/11336/69824
identifier_str_mv Moyano, Mario Franco; Wendel, Graciela Haydée; Trujillo, Liliana del Carmen; Orellano, Guillermo Osvaldo; Fuentes, Lucia Beatriz; Weight gain as a potential risk factor in kidney stones formers; European Centre for Research Training and Development; International Research Journal of Natural Sciences; 3; 4; 12-2015; 54-65
2053-4108
2053-4116
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.eajournals.org/wp-content/uploads/Weight-Gain-as-a-Potential-Risk-Factor-In-Kidney-Stones-Formers.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv European Centre for Research Training and Development
publisher.none.fl_str_mv European Centre for Research Training and Development
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1853775877170528256
score 12.747614

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