La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique...

Autores
Oliveri, María Beatriz; Di Gregorio, Silvana; Parisi, Muriel Solange; Solís, Fabiana; Mautalen, Carlos Alfredo
Año de publicación
2003
Idioma
francés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Corticosteroid treatment diminishes bone mass and alters bone quality. The objective was to evaluate bone in corticosteroid-treated patients and controls and in fractured and non-fractured patients treated with corticosteroids using both X-ray densitometry (DEXA) and ultrasound. We evaluated 34 women aged 58 ± 14 years (X ± SD), who had been on long-term low dose prednisone therapy for at least 6 months, and who had never received specific treatment for osteoporosis. Bone mineral density of total skeleton (TS), lumbar spine (LS), femoral neck (FN), and vertebral morphometry (MXA) were measured by DEXA. Speed of sound (SOS), broadband ultrasound attenuation (BUA) and stiffness were measured using an Achilles Plus system. Forty-two healthy women served as controls. Both densitometric and ultrasound parameters in the patients were significantly diminished compared with controls: TS: P < 0.002, LS: P < 0.025, FS: P < 0.005, Stiffness: P < 0.001, BUA: P < 0.002 and SOS: P < 0.002. The percentage of patients with a Z score below -2 was higher in Stiffness and BUA: 38% and 47%, respectively, compared with a range of 16-24% in the other parameters (P < 0.05 BUA vs. DEXA measurements). Eleven patients with previous bone fracture had values lower than the non-fractured patients, both according to DEXA and ultrasound measurements, but the difference was only significant for BUA (P < 0.02). BUA of the calcaneus was more effective in detecting the specific skeletal alterations and fracture risk of the group of patients receiving chronic corticosteroid treatment.
Fil: Oliveri, María Beatriz. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Di Gregorio, Silvana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
Fil: Parisi, Muriel Solange. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Solís, Fabiana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
Fil: Mautalen, Carlos Alfredo. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
CORTICOSTEROIDS
OSTEOPOROSIS
ULTRASOUND
X-RAY DENSITOMETRY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/123249
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotoniqueIs ultrasound of bone relevant for corticosteroid-treated patients? A comparative study with bone densitometry measured by DEXAOliveri, María BeatrizDi Gregorio, SilvanaParisi, Muriel SolangeSolís, FabianaMautalen, Carlos AlfredoCORTICOSTEROIDSOSTEOPOROSISULTRASOUNDX-RAY DENSITOMETRYhttps://purl.org/becyt/ford/3.5https://purl.org/becyt/ford/3Corticosteroid treatment diminishes bone mass and alters bone quality. The objective was to evaluate bone in corticosteroid-treated patients and controls and in fractured and non-fractured patients treated with corticosteroids using both X-ray densitometry (DEXA) and ultrasound. We evaluated 34 women aged 58 ± 14 years (X ± SD), who had been on long-term low dose prednisone therapy for at least 6 months, and who had never received specific treatment for osteoporosis. Bone mineral density of total skeleton (TS), lumbar spine (LS), femoral neck (FN), and vertebral morphometry (MXA) were measured by DEXA. Speed of sound (SOS), broadband ultrasound attenuation (BUA) and stiffness were measured using an Achilles Plus system. Forty-two healthy women served as controls. Both densitometric and ultrasound parameters in the patients were significantly diminished compared with controls: TS: P < 0.002, LS: P < 0.025, FS: P < 0.005, Stiffness: P < 0.001, BUA: P < 0.002 and SOS: P < 0.002. The percentage of patients with a Z score below -2 was higher in Stiffness and BUA: 38% and 47%, respectively, compared with a range of 16-24% in the other parameters (P < 0.05 BUA vs. DEXA measurements). Eleven patients with previous bone fracture had values lower than the non-fractured patients, both according to DEXA and ultrasound measurements, but the difference was only significant for BUA (P < 0.02). BUA of the calcaneus was more effective in detecting the specific skeletal alterations and fracture risk of the group of patients receiving chronic corticosteroid treatment.Fil: Oliveri, María Beatriz. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; ArgentinaFil: Di Gregorio, Silvana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; ArgentinaFil: Parisi, Muriel Solange. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Solís, Fabiana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; ArgentinaFil: Mautalen, Carlos Alfredo. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2003-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/123249Oliveri, María Beatriz; Di Gregorio, Silvana; Parisi, Muriel Solange; Solís, Fabiana; Mautalen, Carlos Alfredo; La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique; Elsevier; Revue du Rhumatisme (Edition Francaise); 70; 1; 1-2003; 51-571169-8330CONICET DigitalCONICETfrainfo:eu-repo/semantics/altIdentifier/doi/10.1016/S1169-8330(02)00010-8info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1169833002000108info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:55:03Zoai:ri.conicet.gov.ar:11336/123249instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:55:04.071CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
Is ultrasound of bone relevant for corticosteroid-treated patients? A comparative study with bone densitometry measured by DEXA
title La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
spellingShingle La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
Oliveri, María Beatriz
CORTICOSTEROIDS
OSTEOPOROSIS
ULTRASOUND
X-RAY DENSITOMETRY
title_short La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
title_full La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
title_fullStr La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
title_full_unstemmed La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
title_sort La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique
dc.creator.none.fl_str_mv Oliveri, María Beatriz
Di Gregorio, Silvana
Parisi, Muriel Solange
Solís, Fabiana
Mautalen, Carlos Alfredo
author Oliveri, María Beatriz
author_facet Oliveri, María Beatriz
Di Gregorio, Silvana
Parisi, Muriel Solange
Solís, Fabiana
Mautalen, Carlos Alfredo
author_role author
author2 Di Gregorio, Silvana
Parisi, Muriel Solange
Solís, Fabiana
Mautalen, Carlos Alfredo
author2_role author
author
author
author
dc.subject.none.fl_str_mv CORTICOSTEROIDS
OSTEOPOROSIS
ULTRASOUND
X-RAY DENSITOMETRY
topic CORTICOSTEROIDS
OSTEOPOROSIS
ULTRASOUND
X-RAY DENSITOMETRY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.5
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Corticosteroid treatment diminishes bone mass and alters bone quality. The objective was to evaluate bone in corticosteroid-treated patients and controls and in fractured and non-fractured patients treated with corticosteroids using both X-ray densitometry (DEXA) and ultrasound. We evaluated 34 women aged 58 ± 14 years (X ± SD), who had been on long-term low dose prednisone therapy for at least 6 months, and who had never received specific treatment for osteoporosis. Bone mineral density of total skeleton (TS), lumbar spine (LS), femoral neck (FN), and vertebral morphometry (MXA) were measured by DEXA. Speed of sound (SOS), broadband ultrasound attenuation (BUA) and stiffness were measured using an Achilles Plus system. Forty-two healthy women served as controls. Both densitometric and ultrasound parameters in the patients were significantly diminished compared with controls: TS: P < 0.002, LS: P < 0.025, FS: P < 0.005, Stiffness: P < 0.001, BUA: P < 0.002 and SOS: P < 0.002. The percentage of patients with a Z score below -2 was higher in Stiffness and BUA: 38% and 47%, respectively, compared with a range of 16-24% in the other parameters (P < 0.05 BUA vs. DEXA measurements). Eleven patients with previous bone fracture had values lower than the non-fractured patients, both according to DEXA and ultrasound measurements, but the difference was only significant for BUA (P < 0.02). BUA of the calcaneus was more effective in detecting the specific skeletal alterations and fracture risk of the group of patients receiving chronic corticosteroid treatment.
Fil: Oliveri, María Beatriz. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Di Gregorio, Silvana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
Fil: Parisi, Muriel Solange. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Solís, Fabiana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
Fil: Mautalen, Carlos Alfredo. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Corticosteroid treatment diminishes bone mass and alters bone quality. The objective was to evaluate bone in corticosteroid-treated patients and controls and in fractured and non-fractured patients treated with corticosteroids using both X-ray densitometry (DEXA) and ultrasound. We evaluated 34 women aged 58 ± 14 years (X ± SD), who had been on long-term low dose prednisone therapy for at least 6 months, and who had never received specific treatment for osteoporosis. Bone mineral density of total skeleton (TS), lumbar spine (LS), femoral neck (FN), and vertebral morphometry (MXA) were measured by DEXA. Speed of sound (SOS), broadband ultrasound attenuation (BUA) and stiffness were measured using an Achilles Plus system. Forty-two healthy women served as controls. Both densitometric and ultrasound parameters in the patients were significantly diminished compared with controls: TS: P < 0.002, LS: P < 0.025, FS: P < 0.005, Stiffness: P < 0.001, BUA: P < 0.002 and SOS: P < 0.002. The percentage of patients with a Z score below -2 was higher in Stiffness and BUA: 38% and 47%, respectively, compared with a range of 16-24% in the other parameters (P < 0.05 BUA vs. DEXA measurements). Eleven patients with previous bone fracture had values lower than the non-fractured patients, both according to DEXA and ultrasound measurements, but the difference was only significant for BUA (P < 0.02). BUA of the calcaneus was more effective in detecting the specific skeletal alterations and fracture risk of the group of patients receiving chronic corticosteroid treatment.
publishDate 2003
dc.date.none.fl_str_mv 2003-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/123249
Oliveri, María Beatriz; Di Gregorio, Silvana; Parisi, Muriel Solange; Solís, Fabiana; Mautalen, Carlos Alfredo; La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique; Elsevier; Revue du Rhumatisme (Edition Francaise); 70; 1; 1-2003; 51-57
1169-8330
CONICET Digital
CONICET
url http://hdl.handle.net/11336/123249
identifier_str_mv Oliveri, María Beatriz; Di Gregorio, Silvana; Parisi, Muriel Solange; Solís, Fabiana; Mautalen, Carlos Alfredo; La mesure par ultrasons est-elle utile chez les patients traités par corticoïdes ? Étude comparative avec la densité minérale osseuse mesurée par absorptiométrie biphotonique; Elsevier; Revue du Rhumatisme (Edition Francaise); 70; 1; 1-2003; 51-57
1169-8330
CONICET Digital
CONICET
dc.language.none.fl_str_mv fra
language fra
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/S1169-8330(02)00010-8
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1169833002000108
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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